White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases

Autor: Ozzoude, Miracle, Varriano, Brenda, Beaton, Derek, Ramirez, Joel, Adamo, Sabrina, Holmes, Melissa F, Scott, Christopher J M, Gao, Fuqiang, Sunderland, Kelly M, McLaughlin, Paula, Goubran, Maged, Kwan, Donna, Roberts, Angela, Bartha, Robert, Symons, Sean, Tan, Brian, Swartz, Richard H, Abrahao, Agessandro, Saposnik, Gustavo, Masellis, Mario, Lang, Anthony E, Marras, Connie, Zinman, Lorne, Shoesmith, Christen, Borrie, Michael, Fischer, Corinne E, Frank, Andrew, Freedman, Morris, Montero-Odasso, Manuel, Kumar, Sanjeev, Pasternak, Stephen, Strother, Stephen C, Pollock, Bruce G, Rajji, Tarek K, Seitz, Dallas, Tang-Wai, David F, Turnbull, John, Dowlatshahi, Dar, Hassan, Ayman, Casaubon, Leanne, Mandzia, Jennifer, Sahlas, Demetrios, Breen, David P, Grimes, David, Jog, Mandar, Steeves, Thomas D L, Arnott, Stephen R, Black, Sandra E, Finger, Elizabeth, Rabin, Jennifer, Tartaglia, Maria Carmela

Publikováno v: Ozzoude, M, Varriano, B, Beaton, D, Ramirez, J, Adamo, S, Holmes, M F, Scott, C J M, Gao, F, Sunderland, K M, McLaughlin, P, Goubran, M, Kwan, D, Roberts, A, Bartha, R, Symons, S, Tan, B, Swartz, R H, Abrahao, A, Saposnik, G, Masellis, M, Lang, A E, Marras, C, Zinman, L, Shoesmith, C, Borrie, M, Fischer, C E, Frank, A, Freedman, M, Montero-Odasso, M, Kumar, S, Pasternak, S, Strother, S C, Pollock, B G, Rajji, T K, Seitz, D, Tang-Wai, D F, Turnbull, J, Dowlatshahi, D, Hassan, A, Casaubon, L, Mandzia, J, Sahlas, D, Breen, D P, Grimes, D, Jog, M, Steeves, T D L, Arnott, S R, Black, S E, Finger, E & Rabin, J & Tartaglia, M C 2023, ' White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases ', Alzheimer's research & therapy, vol. 15, no. 1, pp. 114 . https://doi.org/10.1186/s13195-023-01257-y

BACKGROUND: Neuropsychiatric symptoms (NPS) are a core feature of most neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain atrophy have been implicated in NPS. We aimed to investigate the relative contribution of w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::6b60e6ab803354588c9121cee7259128
https://hdl.handle.net/20.500.11820/24fa1c84-ed2b-4e7b-bcd0-c07dd7adff84

Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study

Autor: Jose Bernal, Stefanie Schreiber, Inga Menze, Anna Ostendorf, Malte Pfister, Jonas Geisendörfer, Aditya Nemali, Anne Maass, Renat Yakupov, Oliver Peters, Lukas Preis, Luisa Schneider, Ana Lucia Herrera, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Ayda Rostamzadeh, Wenzel Glanz, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, Matthias H. Munk, Annika Spottke, Nina Roy, Laura Dobisch, Peter Dechent, Klaus Scheffler, Stefan Hetzer, Steffen Wolfsgruber, Luca Kleineidam, Matthias Schmid, Moritz Berger, Frank Jessen, Miranka Wirth, Emrah Düzel, Gabriel Ziegler

Publikováno v: Alzheimer's research & therapy 15(1), 97 (2023). doi:10.1186/s13195-023-01243-4
Bernal, J, Schreiber, S, Menze, I, Ostendorf, A, Pfister, M, Geisendörfer, J, Nemali, A, Maass, A, Yakupov, R, Peters, O, Preis, L, Schneider, L, Herrera, A L, Priller, J, Spruth, E J, Altenstein, S, Schneider, A, Fliessbach, K, Wiltfang, J, Schott, B H, Rostamzadeh, A, Glanz, W, Buerger, K, Janowitz, D, Ewers, M, Perneczky, R, Rauchmann, B-S, Teipel, S, Kilimann, I, Laske, C, Munk, M H, Spottke, A, Roy, N, Dobisch, L, Dechent, P, Scheffler, K, Hetzer, S, Wolfsgruber, S, Kleineidam, L, Schmid, M, Berger, M, Jessen, F, Wirth, M, Düzel, E & Ziegler, G 2023, ' Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume : a cross-sectional study ', Alzheimer's research & therapy, vol. 15, no. 1, pp. 97 . https://doi.org/10.1186/s13195-023-01243-4

Background White matter hyperintensities (WMH) in subjects across the Alzheimer’s disease (AD) spectrum with minimal vascular pathology suggests that amyloid pathology—not just arterial hypertension—impacts WMH, which in turn adversely influenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55a0ee7690057eeeb7e3c761b705739

Structural and functional MRI of altered brain development in a novel adolescent rat model of quinpirole-induced compulsive checking behavior

Autor: Milou Straathof, Erwin L.A. Blezer, Caroline van Heijningen, Christel E. Smeele, Annette van der Toorn, Jan K. Buitelaar, Jeffrey C. Glennon, Willem M. Otte, Rick M. Dijkhuizen, Jan Buitelaar, Saskia de Ruiter, Jilly Naaijen, Sophie Akkermans, Maarten Mennes, Marcel Zwiers, Shahrzad Ilbegi, Leonie Hennissen, Jeffrey Glennon, Ilse van de Vondervoort, Katarzyna Kapusta, NaAAtalia Bielczyk, Houshang Amiri, Martha Havenith, Barbara Franke, Geert Poelmans, Janita Bralten, Tom Heskes, Elena Sokolova, Perry Groot, Steven Williams, DeAAclan Murphy, David Lythgoe, Muriel Bruchhage, Iulia Dud, Bogdan Voinescu, Ralf Dittmann, Tobias Banaschewski, Daniel Brandeis, Konstantin Mechler, Ruth Berg, Isabella Wolf, Alexander Häge, Michael Landauer, Sarah Hohmann, Regina Boecker Schlier, Matthias Ruff, René Mandl, Rick Dijkhuizen, Erwin Blezer, Kajo van der Marel, Pim Pullens, Wouter Mol, Willem Otte, Sarah Durston, VinAAcent Mensen, Bob Oranje, Daphna Joel, John Cryan, Tracey Petryshen, David Pauls, Mai Saito, Angelique Heckman, Sabine Bahn, Ameli Schwalber, Ioana Florea

Publikováno v: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 33, 58-70
European Neuropsychopharmacology, 33, 58-70
European Neuropsychopharmacology, 33, pp. 58-70

Obsessive-compulsive disorder (OCD) is increasingly considered to be a neurodevelopmental disorder. However, despite insights in neural substrates of OCD in adults, less is known about mechanisms underlying compulsivity during brain development in ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d8b3e3b92334a9370f69ce9d830093
https://doi.org/10.1016/j.euroneuro.2020.02.004

C-reactive protein and white matter microstructural changes in COVID-19 patients with encephalopathy

Autor: Alexandra Rhally, Marjolaine Uginet, Karl-Olof Lövblad, Patrice H. Lalive, Patrick Stancu, Alessandra Griffa, Stéphane Kremer, Gautier Breville, Frédéric Assal, Gilles Allali

Publikováno v: Journal of Neural Transmission
Journal of neural transmission, Vol. 128, No 12 (2021) pp. 1899-1906
Journal of Neural Transmission, 2021, 128 (12), ⟨10.1007/s00702-021-02429-6⟩

Encephalopathy is a neurological complication of COVID-19. The objective of this exploratory study is to investigate the link between systemic inflammation and brain microstructural changes (measured by diffusion-weighted imaging) in patients with CO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5eb59fab728ffbbff4ca536a4462ae
https://pubmed.ncbi.nlm.nih.gov/34709472

Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs

Autor: Frans R.J. Verhey, Joost J. A. de Jong, Alida A Postma, Inge C.M. Verheggen, Walter H. Backes, Martin P.J. van Boxtel, Jacobus F.A. Jansen

Publikováno v: Fluids and Barriers of the CNS, 17(1):66. BioMed Central
Fluids and Barriers of the CNS
Fluids and barriers of the CNS, 17(1):66. BioMed Central
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-13 (2020)

Background Circumventricular organs (CVOs) are small structures without a blood–brain barrier surrounding the brain ventricles that serve homeostasic functions and facilitate communication between the blood, cerebrospinal fluid and brain. Secretory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf86cfb7c4e5e826fb3eb3156047797
https://research.tue.nl/nl/publications/6f91558b-f484-41e8-96f9-5f02a207a851