Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis.

Autor: White MJV; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA., Ozkan M; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA., Gomez-Medellin JE; Committee on Immunology, University of Chicago, Chicago, IL, 60637, USA., Rączy MM; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA., Koss KM; College of Medicine, University of Arizona, Tucson, AZ, 85724, USA., Solanki A; Animal Resources Center, University of Chicago, Chicago, IL, 60637, USA., Zhang ZJ; Comprehensive Transplant Center & Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Alpar AT; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA., Naved BA; Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Wertheim J; College of Medicine, University of Arizona, Tucson, AZ, 85724, USA., Hubbell JA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.; Committee on Immunology, University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.; Committee on Cancer Biology, University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Sep 16; Vol. 14 (1), pp. 21623. Date of Electronic Publication: 2024 Sep 16.

Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium.

Autor: Naved BA; Medical Science Training Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Bonventre JV; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Hubbell JA; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, Illinois, USA., Hukriede NA; Department of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Humphreys BD; Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA., Kesselman C; Informatics Systems Research Division, Information Sciences Institute, University of Southern California, Los Angeles, California, USA., Valerius MT; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., McMahon AP; Department of Stem Cell Biology and Regenerative Medicine, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Shankland SJ; Division of Nephrology, University of Washington School of Medicine, Seattle, Washington, USA., Wertheim JA; Department of Biomedical Engineering, College of Medicine, The University of Arizona, Tucson, Arizona, USA., White MJV; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, Illinois, USA., de Caestecker MP; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Drummond IA; Davis Center for Regenerative Biology and Aging, Mount Desert Island Biological Laboratory, Bar Harbor, Maine, USA. Electronic address: idrummond@mdibl.org.

Publikováno v: Kidney international [Kidney Int] 2022 May; Vol. 101 (5), pp. 845-853. Date of Electronic Publication: 2022 Mar 09.

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing.

Autor: Ishihara J; Institute for Molecular Engineering, University of Chicago, Chicago, IL.; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; and., Ishihara A; Institute for Molecular Engineering, University of Chicago, Chicago, IL., Starke RD; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, and., Peghaire CR; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, and., Smith KE; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, and., McKinnon TAJ; Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London, United Kingdom., Tabata Y; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; and., Sasaki K; Institute for Molecular Engineering, University of Chicago, Chicago, IL., White MJV; Institute for Molecular Engineering, University of Chicago, Chicago, IL., Fukunaga K; Institute for Molecular Engineering, University of Chicago, Chicago, IL.; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; and., Laffan MA; Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London, United Kingdom., Lutolf MP; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; and., Randi AM; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, and., Hubbell JA; Institute for Molecular Engineering, University of Chicago, Chicago, IL.; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; and.

Publikováno v: Blood [Blood] 2019 Jun 13; Vol. 133 (24), pp. 2559-2569. Date of Electronic Publication: 2019 Apr 11.

Protease activated-receptor 2 is necessary for neutrophil chemorepulsion induced by trypsin, tryptase, or dipeptidyl peptidase IV.

Autor: White MJV; Department of Biology, Texas A&M University, College Station, Texas, USA., Chinea LE; Department of Biology, Texas A&M University, College Station, Texas, USA., Pilling D; Department of Biology, Texas A&M University, College Station, Texas, USA., Gomer RH; Department of Biology, Texas A&M University, College Station, Texas, USA.

Publikováno v: Journal of leukocyte biology [J Leukoc Biol] 2018 Jan; Vol. 103 (1), pp. 119-128. Date of Electronic Publication: 2017 Dec 11.