Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding

Autor: Ozdilek, Bagdeser A., Thompson, Valery F., Ahmed, Nasiha S., White, Connor I., Batey, Robert T., Schwartz, Jacob C.

RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-binding properties remain poorly understood. Here, we report a detailed analysis of the RNA binding characteristics of intrinsically disordered RGG/RG dom

Externí odkaz: http://hdl.handle.net/10150/625471
http://arizona.openrepository.com/arizona/handle/10150/625471

Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding.

Autor: Ozdilek BA; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Campus Box 347, Boulder, CO 80309, USA., Thompson VF; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA., Ahmed NS; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.; Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA., White CI; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA., Batey RT; Department of Chemistry and Biochemistry, University of Colorado, Campus Box 596, Boulder, CO 80309, USA., Schwartz JC; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2017 Jul 27; Vol. 45 (13), pp. 7984-7996.