Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Whijae Roh"'
Autor:
Won-Chul Lee, Alexandre Reuben, Xin Hu, Nicholas McGranahan, Runzhe Chen, Ali Jalali, Marcelo V. Negrao, Shawna M. Hubert, Chad Tang, Chia-Chin Wu, Anthony San Lucas, Whijae Roh, Kenichi Suda, Jihye Kim, Aik-Choon Tan, David H. Peng, Wei Lu, Ximing Tang, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Neda Kalhor, Kazutaka Fukumura, Marcus Coyle, Rebecca Thornton, Curtis Gumbs, Jun Li, Chang-Jiun Wu, Latasha Little, Emily Roarty, Xingzhi Song, J. Jack Lee, Erik P. Sulman, Ganesh Rao, Stephen Swisher, Lixia Diao, Jing Wang, John V. Heymach, Jason T. Huse, Paul Scheet, Ignacio I. Wistuba, Don L. Gibbons, P. Andrew Futreal, Jianhua Zhang, Daniel Gomez, Jianjun Zhang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Metastasis is the primary cause of cancer mortality accounting for 90% of cancer deaths. Our understanding of the molecular mechanisms driving metastasis is rudimentary. Results We perform whole exome sequencing (WES), RNA sequenc
Externí odkaz:
https://doaj.org/article/c29b76fbdc184076acd46b769c6e95c6
Autor:
Akash Mitra, Miles C. Andrews, Whijae Roh, Marianna Petaccia De Macedo, Courtney W. Hudgens, Fernando Carapeto, Shailbala Singh, Alexandre Reuben, Feng Wang, Xizeng Mao, Xingzhi Song, Khalida Wani, Samantha Tippen, Kwok-Shing Ng, Aislyn Schalck, Donald A. Sakellariou-Thompson, Eveline Chen, Sangeetha M. Reddy, Christine N. Spencer, Diana Wiesnoski, Latasha D. Little, Curtis Gumbs, Zachary A. Cooper, Elizabeth M. Burton, Patrick Hwu, Michael A. Davies, Jianhua Zhang, Chantale Bernatchez, Nicholas Navin, Padmanee Sharma, James P. Allison, Jennifer A. Wargo, Cassian Yee, Michael T. Tetzlaff, Wen-Jen Hwu, Alexander J. Lazar, P. Andrew Futreal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Immunotherapies now dominate the treatment landscape for melanoma, but why they only work in a subset of patients remains unclear. Here, the authors perform an immunogenomic analysis on 67 intratumor sub-regions of a PD-1 inhibitor resistant melanoma
Externí odkaz:
https://doaj.org/article/97e9b4c4c8f048e9a752f694b5bd17ef
Autor:
Alexandre Reuben, Christine N. Spencer, Peter A. Prieto, Vancheswaran Gopalakrishnan, Sangeetha M. Reddy, John P. Miller, Xizeng Mao, Mariana Petaccia De Macedo, Jiong Chen, Xingzhi Song, Hong Jiang, Pei-Ling Chen, Hannah C. Beird, Haven R. Garber, Whijae Roh, Khalida Wani, Eveline Chen, Cara Haymaker, Marie-Andrée Forget, Latasha D. Little, Curtis Gumbs, Rebecca L. Thornton, Courtney W. Hudgens, Wei-Shen Chen, Jacob Austin-Breneman, Robert Szczepaniak Sloane, Luigi Nezi, Alexandria P. Cogdill, Chantale Bernatchez, Jason Roszik, Patrick Hwu, Scott E. Woodman, Lynda Chin, Hussein Tawbi, Michael A. Davies, Jeffrey E. Gershenwald, Rodabe N. Amaria, Isabella C. Glitza, Adi Diab, Sapna P. Patel, Jianhua Hu, Jeffrey E. Lee, Elizabeth A. Grimm, Michael T. Tetzlaff, Alexander J. Lazar, Ignacio I. Wistuba, Karen Clise-Dwyer, Brett W. Carter, Jianhua Zhang, P. Andrew Futreal, Padmanee Sharma, James P. Allison, Zachary A. Cooper, Jennifer A. Wargo
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-11 (2017)
Melanoma: Tumor differences within a patient may explain heterogeneous responses Patients with metastatic melanoma display molecular and immune differences across tumor sites associated with differential drug responses. A team led by Jennifer Wargo f
Externí odkaz:
https://doaj.org/article/95f4f8da81aa4220b7ea3fea4b7af4b6
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45023 (2012)
Drug-induced haploinsufficiency (DIH) in yeast has been considered a valuable tool for drug target identification. A plant metabolite, plumbagin, has potent anticancer activity via reactive oxygen species (ROS) generation. However, the detailed molec
Externí odkaz:
https://doaj.org/article/77a3ed44f10847568aaea3c5302d8efd
Autor:
Lawrence N. Kwong, Jennifer A. Wargo, David Y. Zhang, Rodabe N. Amaria, P. Andrew Futreal, Michael A. Davies, Alexander J. Lazar, Jianhua Zhang, Merry Chen, Andrew E. Aplin, Jessica L.F. Teh, Jun Li, Fernando C.L. Carapeto, Dzifa Y. Duose, Whijae Roh, Mingguang Liu, Roger J. Liang, Jennifer L. McQuade, Ping Song, Pei-Ling Chen, Gabriele Romano
Supplementary Figures S1-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9a931537e548752438ad872e3df4eb
https://doi.org/10.1158/2159-8290.22532395
https://doi.org/10.1158/2159-8290.22532395
Autor:
Jennifer A. Wargo, Lynda Chin, James P. Allison, Padmanee Sharma, Jorge Blando, P. Andrew Futreal, Jianhua Hu, Arlene H. Sharpe, Willem W. Overwijk, Wencai Ma, R. Eric Davis, Victor Prieto, Lawrence N. Kwong, Rodabe N. Amaria, Ignacio I. Wistuba, Luis M. Vence, Scott E. Woodman, Isabella C. Glitza, Adi Diab, Wen-Jen Hwu, Patrick Hwu, Sapna P. Patel, Alexander J. Lazar, Lauren Haydu, Jeffrey E. Gershenwald, Michael A. Davies, Russell J. Broaddus, Michael T. Tetzlaff, Wei-Shen Chen, Sangeetha M. Reddy, Qing Chang, Hong Jiang, Jacob L. Austin-Breneman, Mariana Petaccia De Macedo, Khalida Wani, Vancheswaran Gopalakrishnan, Roland L. Bassett, John P. Miller, Peter A. Prieto, Christine N. Spencer, Zachary A. Cooper, Alexandre Reuben, Whijae Roh, Pei-Ling Chen
Supplementary Figure 1. Immune profiling of pre-treatment, on-treatment and progression CTLA-4 blockade samples by immunohistochemistry. Supplementary Figure 2. Myeloid cell profiling of pre-treatment, on-treatment and progression CTLA-4 blockade sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a94b76b26635b304089e2c2105c2324
https://doi.org/10.1158/2159-8290.22531185.v1
https://doi.org/10.1158/2159-8290.22531185.v1
Autor:
Daniel A. Haber, Shyamala Maheswaran, Gad Getz, Shannon L. Stott, Mehmet Toner, David T. Ting, Anders M. Näär, Nir Hacohen, Linda T. Nieman, Michelle K. Jewett, Katherine Calhoun, Laxmi Parida, Samuel S. Freeman, Risa Burr, François Aguet, Chenyue Lu, Todd Bonesteel, Dieuwke L. Marvin, Genevieve M. Boland, Elad Horwitz, Benjamin Wesley, Moshe Sade-Feldman, Taronish D. Dubash, Hongshan Guo, Ben S. Wittner, Keith H.K. Wong, Ryan J. Sullivan, Whijae Roh, Xin Hong
Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35270a83a7467f2e664efd75752c8ad4
https://doi.org/10.1158/2159-8290.22536592
https://doi.org/10.1158/2159-8290.22536592
Autor:
Jennifer A. Wargo, Lynda Chin, James P. Allison, Padmanee Sharma, Jorge Blando, P. Andrew Futreal, Jianhua Hu, Arlene H. Sharpe, Willem W. Overwijk, Wencai Ma, R. Eric Davis, Victor Prieto, Lawrence N. Kwong, Rodabe N. Amaria, Ignacio I. Wistuba, Luis M. Vence, Scott E. Woodman, Isabella C. Glitza, Adi Diab, Wen-Jen Hwu, Patrick Hwu, Sapna P. Patel, Alexander J. Lazar, Lauren Haydu, Jeffrey E. Gershenwald, Michael A. Davies, Russell J. Broaddus, Michael T. Tetzlaff, Wei-Shen Chen, Sangeetha M. Reddy, Qing Chang, Hong Jiang, Jacob L. Austin-Breneman, Mariana Petaccia De Macedo, Khalida Wani, Vancheswaran Gopalakrishnan, Roland L. Bassett, John P. Miller, Peter A. Prieto, Christine N. Spencer, Zachary A. Cooper, Alexandre Reuben, Whijae Roh, Pei-Ling Chen
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3386a59c8445bd1739152486738ced
https://doi.org/10.1158/2159-8290.22531188
https://doi.org/10.1158/2159-8290.22531188
Autor:
Daniel A. Haber, Shyamala Maheswaran, Gad Getz, Shannon L. Stott, Mehmet Toner, David T. Ting, Anders M. Näär, Nir Hacohen, Linda T. Nieman, Michelle K. Jewett, Katherine Calhoun, Laxmi Parida, Samuel S. Freeman, Risa Burr, François Aguet, Chenyue Lu, Todd Bonesteel, Dieuwke L. Marvin, Genevieve M. Boland, Elad Horwitz, Benjamin Wesley, Moshe Sade-Feldman, Taronish D. Dubash, Hongshan Guo, Ben S. Wittner, Keith H.K. Wong, Ryan J. Sullivan, Whijae Roh, Xin Hong
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f8e1b8136568db31ec749753b942ab
https://doi.org/10.1158/2159-8290.22536601.v1
https://doi.org/10.1158/2159-8290.22536601.v1
Autor:
Lawrence N. Kwong, Jennifer A. Wargo, David Y. Zhang, Rodabe N. Amaria, P. Andrew Futreal, Michael A. Davies, Alexander J. Lazar, Jianhua Zhang, Merry Chen, Andrew E. Aplin, Jessica L.F. Teh, Jun Li, Fernando C.L. Carapeto, Dzifa Y. Duose, Whijae Roh, Mingguang Liu, Roger J. Liang, Jennifer L. McQuade, Ping Song, Pei-Ling Chen, Gabriele Romano
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ab075eb949a8a3a77e0c89b228fa1d
https://doi.org/10.1158/2159-8290.22532398
https://doi.org/10.1158/2159-8290.22532398