The G1/S repressor WHI5 is expressed at similar levels throughout the cell cycle

Autor: Sylvain Tollis

Publikováno v: BMC Research Notes, Vol 15, Iss 1, Pp 1-7 (2022)

Abstract Objectives While it is clear that cells need to grow before committing to division at the G1/S transition of the cell cycle, how cells sense their growth rate or size at the molecular level is unknown. It has been proposed that, in budding y

Externí odkaz: https://doaj.org/article/b09d11f9748e4a1193b41d545a86c445

Growth-dependent signals drive an increase in early G1 cyclin concentration to link cell cycle entry with cell growth

Autor: Robert A Sommer, Jerry T DeWitt, Raymond Tan, Douglas R Kellogg

Publikováno v: eLife, Vol 10 (2021)

Entry into the cell cycle occurs only when sufficient growth has occurred. In budding yeast, the cyclin Cln3 is thought to initiate cell cycle entry by inactivating a transcriptional repressor called Whi5. Growth-dependent changes in the concentratio

Externí odkaz: https://doaj.org/article/6996cf857bf7420b95677a3e3cb106c8

Limits and Constraints on Mechanisms of Cell-Cycle Regulation Imposed by Cell Size-Homeostasis Measurements

Autor: Lisa Willis, Henrik Jönsson, Kerwyn Casey Huang

Publikováno v: Cell Reports, Vol 32, Iss 6, Pp 107992- (2020)

Summary: High-throughput imaging has led to an explosion of observations about cell-size homeostasis across the kingdoms of life. Among bacteria, “adder” behavior—in which a constant size increment appears to be added during each cell cycle—i

Externí odkaz: https://doaj.org/article/ef7c78280695464581c58716991e30f7

Growth-dependent signals drive an increase in early G1 cyclin concentration to link cell cycle entry with cell growth

Autor: Robert A. Sommer, Jerry T DeWitt, Douglas R. Kellogg, Raymond Tan

Publikováno v: eLife
eLife, Vol 10 (2021)

Entry into the cell cycle occurs only when sufficient growth has occurred. In budding yeast, the cyclin Cln3 initiates cell cycle entry by inactivating a transcriptional repressor called Whi5. Growth-dependent changes in the concentrations of Cln3 or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52304eb36253162ba45e5a13ae0ceddd
https://escholarship.org/uc/item/5nb5d8qw

The budding yeast Start repressor Whi7 differs in regulation from Whi5, emerging as a major cell cycle brake in response to stress

Autor: Ester Méndez, Manuel Mendoza, Mercè Gomar-Alba, J. Carlos Igual, M. Carmen Bañó, Inma Quilis

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2020, 133 (24), ⟨10.1242/jcs.251413⟩
Journal of Cell Science, 2020, 133 (24), ⟨10.1242/jcs.251413⟩
Méndez Belinchón, Ester Gomar Alba, Mercè Bañó Aracil, María del Carmen Mendoza, Manuel Quilis Bayarri, Inmaculada Igual García, Juan Carlos 2020 The budding yeast Start repressor Whi7 differs in regulation from Whi5, emerging as a major cell cycle brake in response to stress Journal of Cell Science 133 24
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RODERIC: Repositorio Institucional de la Universitat de Valéncia
article-version (VoR) Version of Record

Start is the main decision point in the eukaryotic cell cycle at which cells commit to a new round of cell division. It involves the irreversible activation of a transcriptional programme through the inactivation of Start transcriptional repressors:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424d86db340e2080ea55f54ad1713666
https://hal.archives-ouvertes.fr/hal-03420810