Výsledky vyhledávání - "Whetstine, J. R."

Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway

Autor: Wang, M., Han, J., Marcar, L., Black, J., Liu, Q., Li, X., Nagulapalli, K., Sequist, L. V., Mak, R. H., Benes, C. H., Hong, T. S., Gurtner, K., Krause, M., Baumann, M., Kang, J. X., Whetstine, J. R., Willers, H.

Publikováno v: Cancer Research 77(2017), 2018-2028

Lung cancers with activating KRAS mutations are characterized by treatment resistance and poor prognosis. In particular, the basis for their resistance to radiation therapy is poorly understood. Here, we describe a radiation resistance phenotype conf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::244a3eef6a0da6d13000c8da720b4297
https://www.hzdr.de/publications/Publ-26980-1

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Akademický článek

Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.

Autor: Gifford, A J, Haber, M, Witt, T L, Whetstine, J R, Taub, J W, Matherly, L H, Norris, M D

Publikováno v: Leukemia (08876924); Dec2002, Vol. 16 Issue 12, p2379-2387, 9p

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Akademický článek

Many but not all Genes in Chlamydomonas reinhardtii are Regulated by the Circadian Clock.

Autor: Jacobshagen, S., Whetstine, J. R., Boling, J. M.

Publikováno v: Plant Biology; Nov2001, Vol. 3 Issue 6, p592-597, 6p

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Periodical

Many but not all Genes in Chlamydomonas reinhardtiiare Regulated by the Circadian Clock

Autor: Jacobshagen, S., Whetstine, J. R., Boling, J. M.

Publikováno v: Plant Biology; November 2001, Vol. 3 Issue: 6 p592-597, 6p

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Akademický článek

Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.

Autor: Whetstine JR; Department of Pharmacology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 110 East Warren Avenue, Detroit, MI 48201, USA., Gifford AJ, Witt T, Liu XY, Flatley RM, Norris M, Haber M, Taub JW, Ravindranath Y, Matherly LH

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2001 Nov; Vol. 7 (11), pp. 3416-22.

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Akademický článek

Repression of human reduced folate carrier gene expression by wild type p53.

Autor: Ding BC; Department of Pharmacology and the Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201 , USA., Whetstine JR, Witt TL, Schuetz JD, Matherly LH

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2001 Mar 23; Vol. 276 (12), pp. 8713-9. Date of Electronic Publication: 2000 Dec 05.

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Akademický článek

The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression.

Autor: Whetstine JR; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA., Matherly LH

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2001 Mar 02; Vol. 276 (9), pp. 6350-8. Date of Electronic Publication: 2000 Nov 14.

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Akademický článek

Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans.

Autor: Whetstine JR; Departments of Pharmacology and Clinical Pharmacology, Wayne State University, Detroit, Michigan, USA., Yueh MF, McCarver DG, Williams DE, Park CS, Kang JH, Cha YN, Dolphin CT, Shephard EA, Phillips IR, Hines RN

Publikováno v: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2000 Nov 01; Vol. 168 (3), pp. 216-24.

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