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Proteomic analysis reveals a novel mechanism induced by the leukemic oncogene Tel/PDGFRβ in stem cells: Activation of the interferon response pathways

Autor: Dobbin, E., Graham, C., Freeburn, R.W., Unwin, R.D., Griffiths, J.R., Pierce, A., Whetton, A.D., Wheadon, H.

Publikováno v: In Stem Cell Research 2010 5(3):226-243

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Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma

Autor: Ford, CA, Petrova, S, Pound, JD, Voss, JJ, Melville, L, Paterson, M, Farnworth, SL, Gallimore, AM, Cuff, S, Wheadon, H, Dobbin, E, Ogden, CA, Dumitriu, IE, Dunbar, DR, Murray, PG, Ruckerl, D, Allen, JE, Hume, DA, van Rooijen, N, Goodlad, JR, Freeman, TC, Gregory, CD

Publikováno v: Ford, C A, Petrova, S, Pound, J D, Voss, J J L P, Melville, L, Paterson, M, Farnworth, S L, Gallimore, A M, Cuff, S, Wheadon, H, Dobbin, E, Ogden, C A, Dumitriu, I E, Dunbar, D R, Murray, P G, Rucker, D, Allen, J E, Hume, D A, van Rooijen, N, Goodlad, J R, Freeman, T C & Gregory, C D 2015, ' Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma ', Current Biology, vol. 25, no. 5, pp. 577-588 . https://doi.org/10.1016/j.cub.2014.12.059
Current Biology
Current Biology, 25(5), 577-588. Cell Press

Summary Background Cells undergoing apoptosis are known to modulate their tissue microenvironments. By acting on phagocytes, notably macrophages, apoptotic cells inhibit immunological and inflammatory responses and promote trophic signaling pathways.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::97182ed6dff2075916e01d66a0454fe2
https://research.vumc.nl/en/publications/2b3128a6-aec5-430a-b340-fa16d4ab96da

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis

Autor: Wheadon, H., Ramsey, J.M., Dobbin, E., Dickson, G.J., Corrigan, P.M., Freeburn, R.W., Thompson, A.

The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c9207f6a69c6c536b3092f7e9336d915
https://eprints.gla.ac.uk/66381/1/66381.pdf