Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Whatling P"'
Autor:
Dimitris Kardassis, Ann‐Charlotte Egnell, Magnus Åstrand, Samuel J. Daniels, Carl Whatling, Ola Fjellström, Anders Gabrielsen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 11 (2024)
Background ADP and ATP are importantly involved in vascular and thrombotic homeostasis, via multiple receptor pathways. Blockade of ADP P2Y12 receptors inhibits platelet aggregation and represents an effective cardiovascular disease prevention strate
Externí odkaz:
https://doaj.org/article/aecd06ab5f5540ebbdadb5462edb3d7d
Autor:
Philip Scott, Michaela Heigl, Charles McCay, Polly Shepperdson, Elia Lima‐Walton, Elisavet Andrikopoulou, Klara Brunnhuber, Gary Cornelius, Susan Faulding, Ben McAlister, Shaun Rowark, Matthew South, Mark R. Thomas, Justin Whatling, John Williams, Jeremy C. Wyatt, Felix Greaves
Publikováno v:
Learning Health Systems, Vol 7, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Translating narrative clinical guidelines to computable knowledge is a long‐standing challenge that has seen a diverse range of approaches. The UK National Institute for Health and Care Excellence (NICE) Content Advisory Board
Externí odkaz:
https://doaj.org/article/35c353ac888e4d5eb976dedbbfc2ec55
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Karin Nelander, Maria Lagerstrom‐Fermer, Carl Amilon, Erik Michaëlsson, Maria Heijer, Magnus Kjaer, Muir Russell, David Han, Eva‐Lotte Lindstedt, Carl Whatling, Li‐Ming Gan, Hans Ericsson
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 812-819 (2021)
We evaluated safety, tolerability, pharmacokinetics (PKs), and pharmacodynamics of AZD4831, a novel oral myeloperoxidase (MPO) inhibitor, in a randomized, single‐blind, placebo‐controlled study, following once‐daily multiple ascending dosing to
Externí odkaz:
https://doaj.org/article/56e9be1d8c7f4c148612b0396fe35f83
Autor:
Ariella T. Cohain, William T. Barrington, Daniel M. Jordan, Noam D. Beckmann, Carmen A. Argmann, Sander M. Houten, Alexander W. Charney, Raili Ermel, Katyayani Sukhavasi, Oscar Franzen, Simon Koplev, Carl Whatling, Gillian M. Belbin, Jialiang Yang, Ke Hao, Eimear E. Kenny, Zhidong Tu, Jun Zhu, Li-Ming Gan, Ron Do, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Aldons J. Lusis, Johan L. M. Bjorkegren, Eric E. Schadt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Some cholesterol-lowering drugs can increase the risk of type 2 diabetes, but the mechanism behind this is not fully understood. Here the authors show that there is a single genetic regulatory module that influences both cholesterol levels and glucos
Externí odkaz:
https://doaj.org/article/0c2afd1828064aad921b2b15f3e5c1e2
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262798 (2022)
The primary role of muscles is to move, and control joints. It is therefore important to understand how degenerative joint disease changes this role with the resulting effect on mechanical joint loading. Muscular control strategies can vary depending
Externí odkaz:
https://doaj.org/article/cedb17bc35894ba2af860caf362b4fc8
Autor:
Sparkes V, Whatling GM, Biggs P, Khatib N, Al-Amri M, Williams D, Hemming R, Hagen M, Saleem I, Swaminathan R, Holt C
Publikováno v:
Orthopedic Research and Reviews, Vol Volume 11, Pp 129-140 (2019)
Valerie Sparkes,1 Gemma M Whatling,2,3 Paul Biggs,2,3 Nidal Khatib,2,3 Mohammad Al-Amri,1,3 David Williams,2,3 Rebecca Hemming,1,3 Martina Hagen,4 Ishaak Saleem,2,3 Ramesh Swaminathan,2,3 Cathy Holt2,3 1School of Healthcare Sciences, Biomechanics and
Externí odkaz:
https://doaj.org/article/eb322254d47d44c68e8f0cc21f8a3f7c
Publikováno v:
International Biomechanics, Vol 5, Iss 1, Pp 17-29 (2018)
Manual wheelchair propulsion is an important form of mobility for people with lower limb disabilities. Changes in the wheelchair configuration can affect, range of motion (ROM) of the upper limb joints, muscle actions and system stability. The purpos
Externí odkaz:
https://doaj.org/article/df339839fddb4076b4e9eeef5088097b