Astrocytic Transporters in Alzheimer's disease

Autor: Ugbode, Christopher I., Yuhan, H., Whalley, B.J., Peers, C., Rattray, Marcus, Dallas, M.

Yes
Astrocytes play a fundamental role in maintaining the health and function of the central nervous system. Increasing evidence indicates that astrocytes undergo both cellular and molecular changes at an early stage in neurological diseases, in

Externí odkaz: http://hdl.handle.net/10454/11004

Neuronal-glial populations form functional networks in a biocompatible 3D scaffold.

Autor: Smith, I., Haag, M., Ugbode, Christopher I., Tams, D., Rattray, Marcus, Przyborski, S., Bithell, A., Whalley, B.J.

Yes
Monolayers of neurons and glia have been employed for decades as tools for the study of cellular physiology and as the basis for a variety of standard toxicological assays. A variety of three dimensional (3D) culture techniques have been dev

Externí odkaz: http://hdl.handle.net/10454/7742

Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent

Autor: Gray R.A., Stott C.G., Jones N.A., Di Marzo V., Whalley B.J.

Publikováno v: Cannabis and Cannabinoid Research
Journal of cannabis therapeutics 5 (2020): 145–149. doi:10.1089/can.2019.0028
info:cnr-pdr/source/autori:Gray R.A.; Stott C.G.; Jones N.A.; Di Marzo V.; Di Marzo V.; Whalley B.J.; Whalley B.J./titolo:Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent/doi:10.1089%2Fcan.2019.0028/rivista:Journal of cannabis therapeutics/anno:2020/pagina_da:145/pagina_a:149/intervallo_pagine:145–149/volume:5

Introduction: Highly purified cannabidiol (CBD) (approved as Epidiolex® in the United States) has demonstrated efficacy with an acceptable safety profile in patients with Lennox-Gastaut or Dravet syndrome in four randomized controlled trials. CBD po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ddd661620c82dcc7945ebf17f5440f
https://doi.org/10.1089/can.2019.0028

Further characterization of muscarinic agonist-induced epileptiform bursting activity in immature rat piriform cortex, in vitro

Autor: Whalley, B.J., Postlethwaite, M., Constanti, A.

Publikováno v: In Neuroscience 2005 134(2):549-566

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