Complex patterns of linkage disequilibrium in the Huntington disease region

Autor: MacDonald, M E, Lin, C, Srinidhi, L, Bates, G, Altherr, M, Whaley, W L, Lehrach, H, Wasmuth, J, Gusella, J F

The genetic defect causing Huntington disease (HD) has been mapped to 4p16.3 by linkage analysis using DNA markers. Two apparently contradictory classes of recombination events in HD kindreds preclude precise targeting of efforts to clone the disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::edeba77075a14d2fd07a1a50b051fb56
https://europepmc.org/articles/PMC1683155/

De novo expansion of a (CAG)nrepeat in sporadic Huntington's disease

Autor: Myers, R. H., MacDonald, M. E., Koroshetz, W. J., Duyao, M. P., Ambrose, C. M., Taylor, S. A. M., Barnes, G., Srinidhi, J., Lin, C. S., Whaley, W. L., Lazzarini, A. M., Schwarz, M., Wolff, G., Bird, E. D., Vonsattel, J.-P. G., Gusella, J. F.

Publikováno v: Nature Genetics; October 1993, Vol. 5 Issue: 2 p168-173, 6p

A yeast artificial chromosome telomere clone spanning a possible location of the Huntingon disease gene

Autor: Gillian Bates, Macdonald, M. E., Baxendale, S., Sedlacek, Z., Youngman, S., Romano, D., Whaley, W. L., Allitto, B. A., Poustka, A., Gusella, J. F., Lehrach, H.

Publikováno v: Scopus-Elsevier

The Huntington disease (HD) gene has been mapped to the most distal subband of chromosome 4p. Analysis of recombination events has not provided an unequivocal location of the HD gene, but it indicates a position very close to the telomere as one poss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::41dd04dc281ef9be63361025e22007e6
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025275405&partnerID=MN8TOARS

Huntington disease-linked locus D4S111 exposed as the α-L-iduronidase gene

Autor: Frischauf, A. -M, Gusella, J. F., Hopwood, J. J., Lehrach, H., Macdonald, M. E., Morris, C. P., Pohl, T., Hamish Scott, Wasmuth, J. J., Whaley, W. L.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::23cb020226ee4089304b77d63b4a7f5b
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026048153&partnerID=MN8TOARS

The morphine-binding site on human activated T-cells is not related to the mu opioid receptor.

Autor: Madden JJ; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Emory West Campus, 1256 Briarcliff Road, Atlanta, GA 30306, USA. jmadden@emory.edu, Whaley WL, Ketelsen D, Donahoe RM

Publikováno v: Drug and alcohol dependence [Drug Alcohol Depend] 2001 Apr 01; Vol. 62 (2), pp. 131-9.