A genetic bias in clinical trials? Cytochrome P450-2D6 (CYP2D6) genotype in general vs selected healthy subject populations

Autor: Chen S, Kumar S, Wh, Chou, Jeff Barrett, Pj, Wedlund

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f9fb7ff33b1fcda01c52496be445a62c
https://pubmed.ncbi.nlm.nih.gov/9296329

Characterization of primary Sjögren's syndrome in the Taiwan Han population through a genome-wide association study and polygenic risk score analysis.

Autor: Liu TY; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan., Lin MR; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan., Lu HF; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan., Chen YC; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan., Lin HJ; Department of Ophthalmology, Eye Center, China Medical University Hospital, Taichung 40447, Taiwan., Chou WH; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan., Wei CY; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan., Palupi PD; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan., Liao CC; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan., Chang YT; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan., Chang WC; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan; Master Program in Clinical Genomics and Proteomics, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan; Core Laboratory of Neoantigen Analysis for Personalized Cancer Vaccine, Office of R&D, Taipei Medical University, Taipei 110, Taiwan; Integrative Research Center in Critical Care, Wanfang Hospital, Taipei Medical University, Taipei 116, Taiwan; Department of Pharmacy, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan; Department of Pharmacology, National Defense Medical Center, Taipei 110, Taiwan. Electronic address: wcc@tmu.edu.tw., Tsai FJ; Department of Medical Research, China Medical University Hospital, Taichung 40402, Taiwan; School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; Division of Pediatric Medical Genetics, Children's Hospital of China Medical University, Taichung 40447, Taiwan; Department of Biotechnology and Bioinformatics, Asia University, Taichung 41354, Taiwan. Electronic address: 000704@tool.caaumed.org.tw.

Publikováno v: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2024 Dec; Vol. 269, pp. 110381. Date of Electronic Publication: 2024 Oct 20.

Dietary contributions in the genetic variation of liver fibrosis: a genome-wide association study of fibrosis-4 index in the liver fibrosis development.

Autor: Palupi PD; Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11031, Taiwan., Wei CY; Core Laboratory of Neoantigen Analysis for Personalized Cancer Vaccine, Office of R&D, Taipei Medical University, Taipei, 11031, Taiwan., Chou WH; Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11031, Taiwan., Lin MR; Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11031, Taiwan., Wan YY; Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11031, Taiwan.; Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA., Chang WC; Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11031, Taiwan. weichiao.chang@gmail.com.; Master Program in Clinical Genomics and Proteomics, Taipei Medical University, Taipei, 11031, Taiwan. weichiao.chang@gmail.com.; Integrative Research Center for Critical Care, Department of Pharmacy, Taipei Medical University-Wan-Fang Hospital, Taipei, 11696, Taiwan. weichiao.chang@gmail.com.; Department of Pharmacy, Wan Fang Hospital, Taipei Medical University, Taipei, 11696, Taiwan. weichiao.chang@gmail.com.

Publikováno v: Cell & bioscience [Cell Biosci] 2024 Nov 22; Vol. 14 (1), pp. 141. Date of Electronic Publication: 2024 Nov 22.

Genome-wide association study of hypersensitivity skin reactions induced by nonionic iodinated contrast media.

Autor: Lin MR; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan., Liu TY; Million-person precision medicine initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Hsu HY; Department of Pharmacy, China Medical University Hospital, Taichung, Taiwan., Hsieh YW; Department of Pharmacy, China Medical University Hospital, Taichung, Taiwan., Palupi PD; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan., Chou WH; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan., Lau PP; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan., Chang WC; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan.; Master Program in Clinical Genomics and Proteomics, School of Pharmacy, Taipei Medical University, Taipei, Taiwan.; Integrative Research Center in Critical Care, Wanfang Hospital, Taipei Medical University, Taipei, Taiwan., Tsai FJ; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Division of Pediatric Genetics, Children's Hospital of China Medical University, Taichung, Taiwan.; Department of Biotechnology and Bioinformatics, Asia University, Taichung, Taiwan.

Publikováno v: Asian Pacific journal of allergy and immunology [Asian Pac J Allergy Immunol] 2024 Sep 22. Date of Electronic Publication: 2024 Sep 22.

Influence of substance use on male reproductive health and offspring outcomes.

Autor: Lo JO; Department of Urology, Oregon Heath & Science University, Portland, OR, USA. loj@ohsu.edu.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA. loj@ohsu.edu.; Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR, USA. loj@ohsu.edu., Hedges JC; Department of Urology, Oregon Heath & Science University, Portland, OR, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA.; Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR, USA., Chou WH; Department of Urology, Oregon Heath & Science University, Portland, OR, USA., Tager KR; Department of Environmental Health Science, University of Georgia College of Public Health, Athens, GA, USA., Bachli ID; Department of Environmental Health Science, University of Georgia College of Public Health, Athens, GA, USA., Hagen OL; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Murphy SK; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA., Hanna CB; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Easley CA 4th; Department of Environmental Health Science, University of Georgia College of Public Health, Athens, GA, USA.

Publikováno v: Nature reviews. Urology [Nat Rev Urol] 2024 Sep; Vol. 21 (9), pp. 534-564. Date of Electronic Publication: 2024 Apr 25.