Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wezley C. Griffin"'
Autor:
F. Aaron Cruz-Navarrete, Wezley C. Griffin, Yuk-Cheung Chan, Maxwell I. Martin, Jose L. Alejo, Ryan A. Brady, S. Kundhavai Natchiar, Isaac J. Knudson, Roger B. Altman, Alanna Schepartz, Scott J. Miller, Scott C. Blanchard
Publikováno v:
ACS Central Science, Vol 10, Iss 6, Pp 1262-1275 (2024)
Externí odkaz:
https://doaj.org/article/ba1dc3cf6463484dbb80acadc7def01d
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Achini Eliyapura, Michael A. Trakselis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The MCM8/9 helicase has been implicated in DNA recombination processes with mutations in these genes causative for infertility and cancer. Here, the authors show that MCM8/9 aids normal fork progression and also stabilizes persistently stalled forks,
Externí odkaz:
https://doaj.org/article/b065c20a999744f3b6317e6f71efc98a
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Michael A. Trakselis
The minichromosome maintenance (MCM) 8/9 helicase is a AAA+ complex involved in DNA replication-associated repair. Despite high sequence homology to the MCM2-7 helicase, an active role for MCM8/9 has remained elusive. We interrogated fork progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946417fc44df69538c31400d8c22ef89
https://doi.org/10.1101/2021.12.08.471807
https://doi.org/10.1101/2021.12.08.471807
Autor:
Wezley C. Griffin, David R. McKinzey, Kathleen N. Klinzing, Rithvik Baratam, Achini Eliyapura, Michael A. Trakselis
Publikováno v:
Nature communications. 13(1)
The minichromosome maintenance (MCM) 8/9 helicase is a AAA+ complex involved in DNA replication-associated repair. Despite high sequence homology to the MCM2-7 helicase, a precise cellular role for MCM8/9 has remained elusive. We have interrogated th
Publikováno v:
Chem Res Toxicol
DNA damage and mutations are a major primary cause of cancer. Chemical bombardment of DNA is a major contributor to DNA damage. The Division of Chemical Toxicology recently hosted a panel of researchers who provided updates on the field of chemical t
Publikováno v:
International Journal of Nanomedicine. 14:5159-5173
Introduction: The use of liposomes as a drug delivery carrier (DDC) for the treatment of various diseases, especially cancer, is rapidly increasing, requiring more stringent synthesis, formulation, and preservation techniques to bolster safety and ef
Publikováno v:
Chemical Research in Toxicology
As COVID-19 swept across the world, it created a global pandemic and an unpredictable and challenging job market. This article discusses the future of the 2020-2021 job market in both academia and industry in the midst and aftermath of this pandemic.
Publikováno v:
Journal of Biological Chemistry. 292:9567-9582
DNA sequences that are guanine-rich have received considerable attention because of their potential to fold into a secondary, four-stranded DNA structure termed G-quadruplex (G4), which has been implicated in genomic instability and some human diseas
Publikováno v:
The Enzymes. 45
Hexameric DNA helicases involved in the separation of duplex DNA at the replication fork have a universal architecture but have evolved from two separate protein families. The consequences are that the regulation, translocation polarity, strand speci
Autor:
Michael A. Trakselis, Wezley C Griffin
Publikováno v:
DNA Repair (Amst)
There are several DNA helicases involved in seemingly overlapping aspects of homologous and homoeologous recombination. Mutations of many of these helicases are directly implicated in genetic diseases including cancer, rapid aging, and infertility. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ff24a884615c33e2c7bb26262a7253
https://europepmc.org/articles/PMC9202240/
https://europepmc.org/articles/PMC9202240/