Network topology of NaV1.7 mutations in sodium channel-related painful disorders

Autor: Kapetis D, Sassone J, Yang Y, Galbardi B, Mn, Xenakis, Rl, Westra, Szklarczyk R, Lindsey P, Cg, Faber, Gerrits M, Is, Merkies, Sd, Dib-Hajj, Massimo Mantegazza, Sg, Waxman, Lauria G, Propane, Study Group

Publikováno v: Kapetis, D, Sassone, J, Yang, Y, Galbardi, B, Xenakis, M N, Westra, R L, Szklarczyk, R, Lindsey, P, Faber, C G, Gerrits, M, Merkies, I S J, Dib-Hajj, S D, Mantegazza, M, Waxman, S G, Lauria, G, PROPANE Study Group & Tavakoli, M 2017, ' Network topology of NaV1.7 mutations in sodium channel-related painful disorders ', BMC Systems Biology, vol. 11, no. 1, pp. 28 . https://doi.org/10.1186/s12918-016-0382-0
BMC Systems Biology, 11:28. BioMed Central Ltd
BMC Systems Biology
Europe PubMed Central

Gain-of-function mutations in SCN9A gene that encodes the voltage-gated sodium channel NaV1.7 have been associated with a wide spectrum of painful syndromes in humans including inherited erythromelalgia, paroxysmal extreme pain disorder and small fib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83046e5b0505d9762a2ccfd4ff56eeb7
https://figshare.com/collections/Network_topology_of_NaV1_7_mutations_in_sodium_channel-related_painful_disorders/3703288/1

Hydropathicity-based prediction of pain-causing NaV1.7 variants.

Autor: Xenakis MN; Department of Toxicogenomics, Section Clinical Genomics, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands. mrksxenakis@gmail.com.; Research School for Mental Health and Neuroscience (MHeNS), Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands. mrksxenakis@gmail.com., Kapetis D; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Via Celoria 11, 20133, Milan, Italy., Yang Y; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy, West Lafayette, IN, 47907, USA.; Purdue Institute for Integrative Neuroscience, West Lafayette, IN, 47907, USA., Gerrits MM; Department of Clinical Genetics, Maastricht University Medical Center, PO box 5800, 6202 AZ, Maastricht, The Netherlands., Heijman J; Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands., Waxman SG; Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, 06510, USA.; Rehabilitation Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT, 06516, USA., Lauria G; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Via Celoria 11, 20133, Milan, Italy.; Department of Biomedical and Clinical Sciences 'Luigi Sacco', University of Milan, Via G.B. Grassi 74, 20157, Milan, Italy., Faber CG; Department of Neurology, Maastricht University Medical Center, PO Box 5800, 6202 AZ, Maastricht, The Netherlands., Westra RL; Department of Data Science and Knowledge Engineering, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands., Lindsey PJ; Department of Toxicogenomics, Section Clinical Genomics, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands.; Research School for Oncology and Developmental Biology (GROW), Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands., Smeets HJ; Department of Toxicogenomics, Section Clinical Genomics, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands.; Research School for Mental Health and Neuroscience (MHeNS), Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands.

Publikováno v: BMC bioinformatics [BMC Bioinformatics] 2021 Apr 23; Vol. 22 (1), pp. 212. Date of Electronic Publication: 2021 Apr 23.

Cumulative hydropathic topology of a voltage-gated sodium channel at atomic resolution.

Autor: Xenakis MN; Department of Genetics and Cell Biology, Section Clinical Genomics, Maastricht University, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, the Netherlands., Kapetis D; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy., Yang Y; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy, West Lafayette, Indiana, USA.; Purdue Institute for Integrative Neuroscience, West Lafayette, Indiana, USA., Heijman J; Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands., Waxman SG; Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, Connecticut, USA.; Rehabilitation Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA., Lauria G; Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy.; Department of Biomedical and Clinical Sciences 'Luigi Sacco', University of Milan, Milan, Italy., Faber CG; Department of Neurology, Maastricht University Medical Center, Maastricht, the Netherlands., Smeets HJ; Department of Genetics and Cell Biology, Section Clinical Genomics, Maastricht University, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, the Netherlands., Westra RL; Department of Data Science and Knowledge Engineering, Maastricht University, Maastricht, the Netherlands., Lindsey PJ; Department of Genetics and Cell Biology, Section Clinical Genomics, Maastricht University, Maastricht, the Netherlands.; School for Oncology and Developmental Biology (GROW), Maastricht University, Maastricht, the Netherlands.

Publikováno v: Proteins [Proteins] 2020 Oct; Vol. 88 (10), pp. 1319-1328. Date of Electronic Publication: 2020 Jun 13.

Resonance-driven ion transport and selectivity in prokaryotic ion channels.

Autor: Westra RL; Department of Data Science and Knowledge Engineering, Faculty of Science and Engineering, Maastricht University, Maastricht, The Netherlands.

Publikováno v: Physical review. E [Phys Rev E] 2019 Dec; Vol. 100 (6-1), pp. 062410.

Physiology-based regularization of the electrocardiographic inverse problem.

Autor: Cluitmans MJM; Department of Data Science and Knowledge Engineering and CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands. m.cluitmans@maastrichtuniversity.nl., Clerx M; Department of Data Science and Knowledge Engineering and CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands., Vandersickel N; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Peeters RLM; Department of Data Science and Knowledge Engineering, Maastricht University, Maastricht, The Netherlands., Volders PGA; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands., Westra RL; Department of Data Science and Knowledge Engineering, Maastricht University, Maastricht, The Netherlands.

Publikováno v: Medical & biological engineering & computing [Med Biol Eng Comput] 2017 Aug; Vol. 55 (8), pp. 1353-1365. Date of Electronic Publication: 2016 Nov 21.