The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape.

Autor: Maestri A; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Pons BJ; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Pursey E; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Chong CE; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 7ZB, UK; Department of Genetics, University of Cambridge, Downing Place, Cambridge CB2 3EH, UK., Gandon S; CEFE, CNRS, Université de Montpellier, EPHE, IRD, Montpellier 34293, France., Custodio R; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Olina A; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Agapov A; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Chisnall MAW; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Grasso A; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Paterson S; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 7ZB, UK., Szczelkun MD; DNA-Protein Interactions Unit, School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK., Baker KS; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 7ZB, UK; Department of Genetics, University of Cambridge, Downing Place, Cambridge CB2 3EH, UK., van Houte S; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK., Chevallereau A; Université Paris Cité, CNRS, INSERM, Institut Cochin, Paris 75014, France. Electronic address: anne.chevallereau@cnrs.fr., Westra ER; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn TR10 9FE, UK. Electronic address: E.R.westra@exeter.ac.uk.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2024 Aug 14; Vol. 32 (8), pp. 1412-1426.e11. Date of Electronic Publication: 2024 Aug 01.

Multi-layered genome defences in bacteria.

Autor: Agapov A; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Baker KS; Department of Genetics, University of Cambridge, CB2 3EH, UK., Bedekar P; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Bhatia RP; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Blower TR; Department of Biosciences, Durham University, Stockton Road, Durham DH1 3LE, UK., Brockhurst MA; Division of Evolution, Infection and Genomics, School of Biological Sciences, University of Manchester, Dover Street, Manchester M13 9PT, UK., Brown C; School of Biology, University of St Andrews, St Andrews KY16 9ST, UK., Chong CE; Department of Genetics, University of Cambridge, CB2 3EH, UK., Fothergill JL; Dept of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK., Graham S; School of Biology, University of St Andrews, St Andrews KY16 9ST, UK., Hall JP; Dept of Evolution, Ecology and Behaviour, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, L69 7ZB, UK., Maestri A; ESI, Centre for Ecology and Conservation, University of Exeter, UK., McQuarrie S; School of Biology, University of St Andrews, St Andrews KY16 9ST, UK., Olina A; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Pagliara S; LSI, University of Exeter, UK., Recker M; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Richmond A; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Shaw SJ; DNA-Protein Interactions Unit, School of Biochemistry, University of Bristol, Bristol BS6 7YB, UK., Szczelkun MD; DNA-Protein Interactions Unit, School of Biochemistry, University of Bristol, Bristol BS6 7YB, UK., Taylor TB; Milner Centre for Evolution, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK., van Houte S; ESI, Centre for Ecology and Conservation, University of Exeter, UK., Went SC; Department of Biosciences, Durham University, Stockton Road, Durham DH1 3LE, UK., Westra ER; ESI, Centre for Ecology and Conservation, University of Exeter, UK. Electronic address: E.R.Westra@exeter.ac.uk., White MF; School of Biology, University of St Andrews, St Andrews KY16 9ST, UK., Wright R; Division of Evolution, Infection and Genomics, School of Biological Sciences, University of Manchester, Dover Street, Manchester M13 9PT, UK.

Publikováno v: Current opinion in microbiology [Curr Opin Microbiol] 2024 Apr; Vol. 78, pp. 102436. Date of Electronic Publication: 2024 Feb 17.

Conditions for the spread of CRISPR-Cas immune systems into bacterial populations.

Autor: Elliott JFK; Milner Centre for Evolution, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom.; ESI, Biosciences, University of Exeter, Cornwall Campus, Penryn TR10 9FE, United Kingdom., McLeod DV; Département de mathématiques et statistique, Université de Montréal, Montréal, Canada.; Institute of Ecology and Evolution, Universität Bern, Bern, Switzerland., Taylor TB; Milner Centre for Evolution, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom., Westra ER; ESI, Biosciences, University of Exeter, Cornwall Campus, Penryn TR10 9FE, United Kingdom., Gandon S; CEFE, CNRS, Univ Montpellier, EPHE, IRD, Montpellier, France., Watson BNJ; ESI, Biosciences, University of Exeter, Cornwall Campus, Penryn TR10 9FE, United Kingdom.

Publikováno v: The ISME journal [ISME J] 2024 Jan 08; Vol. 18 (1).

The impact of phage and phage resistance on microbial community dynamics.

Autor: Alseth EO; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn, UK.; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Custodio R; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn, UK., Sundius SA; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.; School of Math, Georgia Institute of Technology, Atlanta, Georgia, USA.; Interdisciplinary Program in Quantitative Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Kuske RA; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.; School of Math, Georgia Institute of Technology, Atlanta, Georgia, USA., Brown SP; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Westra ER; Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn, UK.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 26. Date of Electronic Publication: 2023 Sep 26.

Slow growing bacteria survive bacteriophage in isolation.

Autor: Attrill EL; Living Systems Institute and Biosciences, University of Exeter, Exeter, UK., Łapińska U; Living Systems Institute and Biosciences, University of Exeter, Exeter, UK., Westra ER; Environment and Sustainability Institute and Biosciences, University of Exeter, Penryn, UK., Harding SV; Defence Science and Technology Laboratory, Porton Down, Salisbury, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Pagliara S; Living Systems Institute and Biosciences, University of Exeter, Exeter, UK. s.pagliara@exeter.ac.uk.

Publikováno v: ISME communications [ISME Commun] 2023 Sep 08; Vol. 3 (1), pp. 95. Date of Electronic Publication: 2023 Sep 08.