Zobrazeno 1 - 10
of 12 029
pro vyhledávání: '"Westra A"'
Autor:
Olivier B. Bakker, Annique Claringbould, Harm-Jan Westra, Henry Wiersma, Floranne Boulogne, Urmo Võsa, Carlos G. Urzúa-Traslaviña, Sophie Mulcahy Symmons, Mahmoud M. M. Zidan, Marie C. Sadler, Zoltán Kutalik, Iris H. Jonkers, Lude Franke, Patrick Deelen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Genetic variants identified through genome-wide association studies (GWAS) are typically non-coding, exerting small regulatory effects on downstream genes. However, which downstream genes are ultimately impacted and how they confer risk rema
Externí odkaz:
https://doaj.org/article/9ce5ca1daf92482e81d7d7d7db513a2a
Autor:
Iris M. Westra, Hubertus A. Scheeren, Firmin T. Stroo, Steven M. A. C. van Heuven, Bert A. M. Kers, Wouter Peters, Harro A. J. Meijer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Projections towards 2050 of the global hydrogen (H2) demand indicate an eight-fold increase in present-day hydrogen consumption. Leakage during production, transport, and consumption therefore presents a large potential for increases in the
Externí odkaz:
https://doaj.org/article/50f6054d14e14730bff74b4789cede11
Autor:
Nicotra, Davide, Martinez, Miriam Lucio, de Vries, Jacco Andreas, Merk, Marcel, Driessens, Kurt, Westra, Ronald Leonard, Dibenedetto, Domenica, Pérez, Daniel Hugo Cámpora
High-energy physics is facing increasingly computational challenges in real-time event reconstruction for the near-future high-luminosity era. Using the LHCb vertex detector as a use-case, we explore a new algorithm for particle track reconstruction
Externí odkaz:
http://arxiv.org/abs/2308.00619
Autor:
Jiafei Wu, Victoria Palasantzas, Sergio Andreu-Sánchez, Torsten Plösch, Sam Leonard, Shuang Li, Marc Jan Bonder, Harm-Jan Westra, Joyce van Meurs, Mohsen Ghanbari, Lude Franke, Alexandra Zhernakova, Jingyuan Fu, Joanne A. Hoogerland, Daria V. Zhernakova
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background The plasma metabolome reflects the physiological state of various biological processes and can serve as a proxy for disease risk. Plasma metabolite variation, influenced by genetic and epigenetic mechanisms, can also affect the ce
Externí odkaz:
https://doaj.org/article/9ba2686e25cc4689806e48f764522f07
Autor:
Carlos G. Urzúa-Traslaviña, Tijs van Lieshout, Floranne Boulogne, Kevin Domanegg, Mahmoud Zidan, Olivier B. Bakker, Annique Claringbould, Jeroen de Ridder, Wilbert Zwart, Harm-Jan Westra, Patrick Deelen, Lude Franke
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background The genetic background of cancer remains complex and challenging to integrate. Many somatic mutations within genes are known to cause and drive cancer, while genome-wide association studies (GWAS) of cancer have revealed many germ
Externí odkaz:
https://doaj.org/article/87d4375406f84fe0ab53a48e271de9a9
Autor:
Siqi Liu, Johanna Westra, Shixian Hu, Erik A. M. Verschuuren, Léon C. van Kempen, Debbie van Baarle, Nico A. Bos
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
The acute rejection (AR) diagnosis depends on transbronchial biopsy, which is semi-invasive and not easily performed. Our study used the Nanostring gene expression technology on PBMCs obtained from lung transplant recipients (LTRs) to search for biom
Externí odkaz:
https://doaj.org/article/5ead7b7bd790408287110aae0da29df1
Autor:
Howard L McLeod, A Dimitrios Colevas, Georges Azzi, Kevin C Flanagan, Douglas Adkins, Jessica Ley, Ezra E W Cohen, James Wade, Jon Earls, Jeffrey Hiken, Rachel L Wellinghoff, Michelle M Ponder, William H Westra, Vera Vavinskaya, Leisa Sutton, Ida Deichaite, Orlan K Macdonald, Karim Welaya, Andrew W Pippas, Jennifer Slim, Bruce Bank, Xingwei Sui, Steven E Kossman, Todd D Shenkenberg, Warren L Alexander, Katharine A Price, David N Messina, Jarret I Glasscock, Eric J Duncavage
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Despite advances in cancer care and detection, >65% of patients with squamous cell cancer of the head and neck (HNSCC) will develop recurrent and/or metastatic disease. The prognosis for these patients is poor with a 5-year overall surviva
Externí odkaz:
https://doaj.org/article/5aeea84f23854b819fffb4fd1e4886a8
Publikováno v:
Research and Theory to Foster Change in the Face of Grand Health Care Challenges
Publikováno v:
Research and Theory to Foster Change in the Face of Grand Health Care Challenges
Autor:
Westra, Iris M.1 (AUTHOR) i.m.westra@rug.nl, Scheeren, Hubertus A.1 (AUTHOR), Stroo, Firmin T.1 (AUTHOR), van Heuven, Steven M. A. C.1 (AUTHOR), Kers, Bert A. M.1 (AUTHOR), Peters, Wouter1,2 (AUTHOR), Meijer, Harro A. J.1 (AUTHOR)
Publikováno v:
Scientific Reports. 10/15/2024, Vol. 14 Issue 1, p1-13. 13p.