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Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids

Autor: Slingerland, Cornelis J., Wesseling, Charlotte M. J., Innocenti, Paolo, Westphal, Koen G. C., Masereeuw, Rosalinde, Martin, Nathaniel I., Afd Chemical Biology and Drug Discovery, Afd Pharmacology, Chemical Biology and Drug Discovery, Pharmacology

Publikováno v: Journal of Medicinal Chemistry. AMER CHEMICAL SOC
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 65(23), 15878-15892. American Chemical Society (ACS)
Journal of Medicinal Chemistry, 65(23). American Chemical Society : Division of Carbohydrate Chemistry

Polymyxins are a class of lipopeptide anti-infective agents with potent and specific activity against Gram-negative bacteria. While toxicity concerns associated with polymyxin B and E (colistin) have historically limited their clinical application, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b9e98a038752edb0c1e0999cf52137
https://dspace.library.uu.nl/handle/1874/424682

Lipopolysaccharide increases degradation of central monoamines: An in vivo microdialysis study in the nucleus accumbens and medial prefrontal cortex of mice

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Publikováno v: In European Journal of Pharmacology 15 February 2014 725:55-63

Minocycline restores spatial but not fear memory in olfactory bulbectomized rats

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Publikováno v: In European Journal of Pharmacology 15 December 2012 697(1-3):59-64

Re-exposure and environmental enrichment reveal NPY-Y1 as a possible target for post-traumatic stress disorder

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