Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Weston R. Spivia"'
Autor:
Jennifer E. Van Eyk, Amanda Orosco, Sarah J. Parker, Aleksandr Stotland, Roberta A. Gottlieb, Allen M. Andres, Weston R. Spivia
Publikováno v:
J Mol Cell Cardiol
Mitochondria are the major source of cellular energy (ATP), as well as critical mediators of widespread functions such as cellular redox balance, apoptosis, and metabolic flux. The organelles play an especially important role in the maintenance of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fca6883346e9393c924edb0b884abb3
https://doi.org/10.1016/j.yjmcc.2020.03.011
https://doi.org/10.1016/j.yjmcc.2020.03.011
Publikováno v:
Environmental Pollution. 223:42-50
Chronic organochlorine (OC) exposure has been shown to cause immune impairment in numerous vertebrate species. To determine if elasmobranchs exhibited compromised immunity due to high OC contamination along the coastal mainland of southern California
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffc25e485bb1f1c0a6842cbb2a84a14
https://doi.org/10.1016/j.envpol.2016.12.019
https://doi.org/10.1016/j.envpol.2016.12.019
Autor:
Roberta A. Gottlieb, Helen B. Burks, Anja Karlstaedt, Rebecca Salazar, Jennifer VanEyk, David J. Taylor, An Dinh, Benjamin D. Gould, Daniel Soetkamp, Walter Schiffer, Blake Hanson, Heinrich Taegtmeyer, Weston R. Spivia, Daniel McNavish, Koen Raedschelders, Heidi Vitrac
Publikováno v:
Circulation Research. 125
Metabolic rewiring is a hallmark of cancer and muscle cells. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, including myopathy. Our r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e590eb88f724176a5a658c1fe101f6
https://doi.org/10.1161/res.125.suppl_1.361
https://doi.org/10.1161/res.125.suppl_1.361
Autor:
Weston R. Spivia, Jennifer E. Van Eyk, Karyn S. Eilber, Qin Fu, Michael R. Freeman, Jayoung Kim, A. Lenore Ackerman, Jennifer T. Anger
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) network is, to date, the largest cohort study of men and women with urologic chronic pelvic pai...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a3d85a96945faf5c1270b8e996f572
https://doi.org/10.1097/01.ju.0000556318.92548.8e
https://doi.org/10.1097/01.ju.0000556318.92548.8e
Autor:
Clive N. Svendsen, Dawn Chen, Jennifer E. Van Eyk, Bin Lu, Augustus T. Mercado, Shaomei Wang, Melissa Kaye Jones, Weston R. Spivia, Alexander V. Ljubimov
Publikováno v:
Proteomics, vol 19, iss 3
Retinal degenerative diseases lead to blindness with few treatments. Various cell-based therapies are aimed to slow the progression of vision loss by preserving light-sensing photoreceptor cells. A subretinal injection of human neural progenitor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c3bec4d4136f6a2f020710e5260c6f
https://escholarship.org/uc/item/3sh6b9kw
https://escholarship.org/uc/item/3sh6b9kw
Autor:
Weston R. Spivia, Koen Raedschelders, Anja Karlstaedt, Jennifer VanEyk, Heinrich Taegtmeyer, Daniel M, Radhika Khanna, Heidi Vitrac
Publikováno v:
Circulation Research. 123
Autophagy “scavenges” proteins and yields amino acids under conditions of metabolic stress to support cell survival and growth. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee45a6b884a7d4a16361c4e083f4c677
https://doi.org/10.1161/res.123.suppl_1.452
https://doi.org/10.1161/res.123.suppl_1.452
Autor:
Vidya Venkatraman, Sarah J. Parker, Richard S. Vander Heide, Zongming Fu, Grace Athas, Timothy D. Howard, Yongmei Liu, Jennifer E. Van Eyk, David M. Herrington, Dana Troxclair, Yue Wang, Yi Fu, Georgia Saylor, Goo Jun, Weston R. Spivia, Caroline F. Zhao, Lulu Chen, Chunhong Mao, Yizhi Wang, Guoqiang Yu, James E. Hixson
Backgound: The inability to detect premature atherosclerosis significantly hinders implementation of personalized therapy to prevent coronary heart disease. A comprehensive understanding of arterial protein networks and how they change in early ather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c99a5730a2979ceeceb4c5acedf035
https://europepmc.org/articles/PMC6011234/
https://europepmc.org/articles/PMC6011234/
Autor:
Jennifer E. Van Eyk, Magdalena Kasendra, Michael J. Workman, Matthew Rahnama, Zhaohui Chen, Weston R. Spivia, Jordan Kerns, Carolina Lucchesi, Sonalee Barthakur, Gad D. Vatine, Clive N. Svendsen, Samuel Sances, Bianca K. Barriga, Norman Wen, Riccardo Barrile
Publikováno v:
Cell Stem Cell. 24:995-1005.e6
Summary The blood-brain barrier (BBB) tightly regulates the entry of solutes from blood into the brain and is disrupted in several neurological diseases. Using Organ-Chip technology, we created an entirely human BBB-Chip with induced pluripotent stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e146bc4f2f5ed9b57c38cb3dfd4bb9f0
https://doi.org/10.1016/j.stem.2019.05.011
https://doi.org/10.1016/j.stem.2019.05.011
Autor:
Shaomei Wang, Weston R. Spivia, Dawn Chen, Melissa Kaye Jones, Clive N. Svendsen, Jennifer E. Van Eyk, Bin Lu, Alexander V. Ljubimov, Augustus T. Mercado
Publikováno v:
PROTEOMICS. 19:1970011
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e1127558c14b2d87200d38c322034b5
https://doi.org/10.1002/pmic.201970011
https://doi.org/10.1002/pmic.201970011
Publikováno v:
Atherosclerosis. 253
Background and aims This study investigated the effect of innate immune protein C1q on macrophage programmed responses during the ingestion of atherogenic lipoproteins. C1q plays a dual role in atherosclerosis where activation of complement by C1q is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9575b492a9546565be5f4a3ed062c25
https://pubmed.ncbi.nlm.nih.gov/27573737
https://pubmed.ncbi.nlm.nih.gov/27573737