Visualization of arrestin recruitment by a G-protein-coupled receptor.

Autor: Shukla AK; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Westfield GH; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Xiao K; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Reis RI; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Huang LY; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Tripathi-Shukla P; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Qian J; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Li S; Department of Chemistry, University of California at San Diego, La Jolla, CA 92093, USA., Blanc A; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Oleskie AN; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Dosey AM; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Su M; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Liang CR; School of Pharmaceutical & Life Sciences, Changzhou University, Changzhou, Jiangsu 213164, China., Gu LL; School of Pharmaceutical & Life Sciences, Changzhou University, Changzhou, Jiangsu 213164, China., Shan JM; School of Pharmaceutical & Life Sciences, Changzhou University, Changzhou, Jiangsu 213164, China., Chen X; School of Pharmaceutical & Life Sciences, Changzhou University, Changzhou, Jiangsu 213164, China., Hanna R; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Choi M; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA., Yao XJ; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Klink BU; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Kahsai AW; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA., Sidhu SS; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada., Koide S; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA., Penczek PA; Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston, Houston, TX 77054, USA., Kossiakoff AA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA., Woods VL Jr; Department of Chemistry, University of California at San Diego, La Jolla, CA 92093, USA., Kobilka BK; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, USA., Skiniotis G; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Lefkowitz RJ; Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.; Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710, USA.

Publikováno v: Nature [Nature] 2014 Aug 14; Vol. 512 (7513), pp. 218-222. Date of Electronic Publication: 2014 Jun 22.

Ligand-induced architecture of the leptin receptor signaling complex.

Autor: Mancour LV; Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109, USA., Daghestani HN, Dutta S, Westfield GH, Schilling J, Oleskie AN, Herbstman JF, Chou SZ, Skiniotis G

Publikováno v: Molecular cell [Mol Cell] 2012 Nov 30; Vol. 48 (4), pp. 655-61. Date of Electronic Publication: 2012 Oct 11.

Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.

Autor: Westfield GH; Life Sciences Institute and Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL Jr, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Sep 20; Vol. 108 (38), pp. 16086-91. Date of Electronic Publication: 2011 Sep 13.