Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Western blot assay"'
Autor:
N. S. Finiuk, O. Yu. Klyuchivska, H. M. Kuznietsova, S. P. Vashchuk, V. K. Rybalchenko, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 14, Iss 4, Pp 3-14 (2020)
Background. The heterocyclic scaffolds are in the list of key structural blocks used at synthesis of novel biologically active compounds. Materials and Methods. The present study addressed the evaluation of the mechanisms of the DNA damaging and p
Externí odkaz:
https://doaj.org/article/af695640bb6048c3b302d7ba5d9b579b
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1510-1517 (2020)
Acupuncture is widely used in the treatment of cerebral hemorrhage, and it improves outcomes in experimental animal models and patients. However, the mechanisms underlying the effectiveness of acupuncture treatment for cerebral hemorrhage are still u
Externí odkaz:
https://doaj.org/article/ba47fcd21ffc466a9b17f5a37a6e157f
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 5, Pp 775-782 (2019)
Constraint-induced movement therapy is an effective rehabilitative training technique used to improve the restoration of impaired upper extremity movement after stroke. However, whether constraint-induced movement therapy is more effective than conve
Externí odkaz:
https://doaj.org/article/a64fe5768b4344a0bab7c49961bc9d12
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 12, Pp 2147-2155 (2019)
Optogenetics is a combination of optics and genetics technology that can be used to activate or inhibit specific cells in tissues. It has been used to treat Parkinson’s disease, epilepsy and neurological diseases, but rarely Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/adf75b801f72405a88cc8edb66612945
Autor:
Sai-Nan Wang, Xue-Yan Guo, Jie Tang, Shu-Qin Ding, Lin Shen, Rui Wang, Shan-Feng Ma, Jian-Guo Hu, He-Zuo Lü
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 542-552 (2019)
In traumatic brain injury, absent in melanoma 2 (AIM2) has been demonstrated to be involved in pyroptotic neuronal cell death. Although the pathophysiological mechanism of spinal cord injury is similar to that of brain injury, the expression and cell
Externí odkaz:
https://doaj.org/article/29e2d5ba6b924690b4f7017a6a07c61f
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 4, Pp 677-683 (2018)
Rho-associated kinase (ROCK) is a key regulatory protein involved in inflammatory secretion in microglia in the central nervous system. Our previous studies showed that ROCK inhibition enhances phagocytic activity in microglia through the extracellul
Externí odkaz:
https://doaj.org/article/9d96c7ff524c4e178e5f54ff2803465a
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 7, Pp 1124-1130 (2017)
Signal transducer and activator of transcription (STAT) is a unique protein family that binds to DNA, coupled with tyrosine phosphorylation signaling pathways, acting as a transcriptional regulator to mediate a variety of biological effects. Cerebral
Externí odkaz:
https://doaj.org/article/024398b361784ee49997cfccc3ba0bb7
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 3, Pp 464-469 (2017)
Estrogen affects the generation and transmission of neuropathic pain, but the specific regulatory mechanism is still unclear. Activation of the N-methyl-D-aspartate acid receptor 1 (NMDAR1) plays an important role in the production and maintenance of
Externí odkaz:
https://doaj.org/article/aad0e3287f8942d293b78189dafaa586
Autor:
You-jiang Min, Li-li-qiang Ding, Li-hong Cheng, Wei-ping Xiao, Xing-wei He, Hui Zhang, Zhi-yun Min, Jia Pei
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 2, Pp 276-282 (2017)
Electroacupuncture is beneficial for the recovery of spinal cord injury, but the underlying mechanism is unclear. The Rho/Rho-associated kinase (ROCK) signaling pathway regulates the actin cytoskeleton by controlling the adhesive and migratory behavi
Externí odkaz:
https://doaj.org/article/23ed95d344624aef96b9a17c8f10ae3d
Autor:
Xin Lai, Liang Zhong, Hai-xia Fu, Song Dang, Xin Wang, Ning Zhang, Gao-ke Feng, Zi-qiang Liu, Xi Wang, Long Wang
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 11, Pp 1905-1910 (2017)
Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction (MI). Increasing evidence indicates that neuregulin-1 (NRG-1) improves cardiac function following heart failure. Since its impact on ca
Externí odkaz:
https://doaj.org/article/2c3dd6bd17c04ac0956401d13828221e