Zobrazeno 1 - 10
of 533
pro vyhledávání: '"Westergren-Thorsson Gunilla"'
Autor:
Ryde Martin, Marek Nora, Löfdahl Anna, Pekny Olivia, Bjermer Leif, Westergren-Thorsson Gunilla, Tufvesson Ellen, Larsson-Callerfelt Anna-Karin
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by chronic bronchitis, emphysema and vascular remodelling. The disease is associated with hypoxia, inflammation and oxidative stress. Lung fibro
Externí odkaz:
https://doaj.org/article/232d54a57df74f7c8ae8179775779f75
Autor:
Larsson-Callerfelt Anna-Karin, Hallgren Oskar, Andersson-Sjöland Annika, Thiman Lena, Björklund Johan, Kron Josefine, Nihlberg Kristian, Bjermer Leif, Löfdahl Claes-Göran, Westergren-Thorsson Gunilla
Publikováno v:
Respiratory Research, Vol 14, Iss 1, p 21 (2013)
Abstract Background Prostacyclin analogs are potent vasodilators and possess anti-inflammatory properties. However, the effect of prostacyclin on extracellular matrix (ECM) in COPD is not well known. Collagen fibrils and proteoglycans are essential E
Externí odkaz:
https://doaj.org/article/26320a98cd7b424d9aa50ce2299bfbf1
Autor:
Hallgren Oskar, Rolandsson Sara, Andersson-Sjöland Annika, Nihlberg Kristian, Wieslander Elisabet, Kvist-Reimer Martina, Dahlbäck Magnus, Eriksson Leif, Bjermer Leif, Erjefält Jonas S, Löfdahl Claes-Göran, Westergren-Thorsson Gunilla
Publikováno v:
Journal of Translational Medicine, Vol 10, Iss 1, p 171 (2012)
Abstract Background During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls and our hypothesis is
Externí odkaz:
https://doaj.org/article/88d7809b904a45ae95bf266681474140
Autor:
Löfdahl Claes-Göran, Bjermer Leif, Eriksson Leif, Pardo Annie, Hallgren Oskar, Mori Michiko, Andersson-Sjöland Annika, Andersson Cecilia K, Selman Moises, Westergren-Thorsson Gunilla, Erjefält Jonas S
Publikováno v:
Respiratory Research, Vol 12, Iss 1, p 139 (2011)
Abstract Background Although mast cells are regarded as important regulators of inflammation and tissue remodelling, their role in cystic fibrosis (CF) and idiopathic pulmonary fibrosis (IPF) has remained less studied. This study investigates the den
Externí odkaz:
https://doaj.org/article/8759b4c142314994ad04dec5b552e65d
Autor:
Bjermer Leif, Eriksson Leif, Nihlberg Kristian, Andersson-Sjöland Annika, Westergren-Thorsson Gunilla
Publikováno v:
Respiratory Research, Vol 12, Iss 1, p 76 (2011)
Abstract Human fibrocytes are bone marrow-derived mesenchymal progenitor cells that express a variety of markers related to leukocytes, hematopoietic stem cells and a diverse set of fibroblast phenotypes. Fibrocytes can be recruited from the circulat
Externí odkaz:
https://doaj.org/article/0bd2f2f4ed374e59988907755482a626
Autor:
Erjefält Jonas S, Eriksson Leif T, Bjermer Leif, Dahlbäck Magnus, Nihlberg Kristian, Hallgren Oskar, Löfdahl Claes-Göran, Westergren-Thorsson Gunilla
Publikováno v:
Respiratory Research, Vol 11, Iss 1, p 55 (2010)
Abstract Background Airway remodeling in COPD includes reorganization of the extracellular matrix. Proteoglycans play a crucial role in this process as regulators of the integrity of the extracellular matrix. Altered proteoglycan immunostaining has b
Externí odkaz:
https://doaj.org/article/a498868697cb4e669626f1d07fd9799e
Autor:
Bjermer Leif, Erjefält Jonas S, Andersson-Sjöland Annika, Eriksson Leif, Westergren-Thorsson Gunilla
Publikováno v:
Respiratory Research, Vol 10, Iss 1, p 103 (2009)
Abstract Background The aim of the present study was to explore the occurrence of fibrocytes in tissue and to investigate whether the appearance of fibrocytes may be linked to structural changes of the parenchyme and vasculature in the lungs of patie
Externí odkaz:
https://doaj.org/article/fd2dc7aaa5164ca6bae609eeb3514968
Autor:
Laurell Thomas, Westergren-Thorsson Gunilla, Marko-Varga György, Malmström Lars, Malmström Johan
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 158 (2006)
Abstract Background We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is produced increases in the proteomics field, the need for flexib
Externí odkaz:
https://doaj.org/article/c8cd5291afc34036bd5322ad92349c10
Autor:
Bjermer Leif, Malmström Anders, Hultgårdh-Nilsson Anna, Larsen Kristoffer, Nihlberg Kristian, Westergren-Thorsson Gunilla
Publikováno v:
Respiratory Research, Vol 7, Iss 1, p 50 (2006)
Abstract Background Myofibroblasts, proposed as being derived from circulating fibrocytes, are considered to be important cells in thickening of the basement membrane in patients with asthma. We have studied the correlation of tissue fibrocyte levels
Externí odkaz:
https://doaj.org/article/6feba5e6f6b5421d84d1adb287ecb192