Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Westendorp, Bart"'
Autor:
Veth, Tim S., Nouwen, Lonneke V., Zwaagstra, Marleen, Lyoo, Heyrhyoung, Wierenga, Kathryn A., Westendorp, Bart, Altelaar, Maarten A.F.M., Berkers, Celia, van Kuppeveld, Frank J.M., Heck, Albert J.R.
Publikováno v:
In Molecular & Cellular Proteomics May 2024 23(5)
Akademický článek
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Autor:
Westendorp, Bart1,2 b.westendorp@uu.nl
Publikováno v:
Science. 5/3/2024, Vol. 384 Issue 6695, p512-513. 2p. 1 Diagram.
Akademický článek
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Autor:
Moreno, Eva, Matondo, Augustine B, Bongiovanni, Laura, van de Lest, Chris H A, Molenaar, Martijn R, Toussaint, Mathilda J M, van Essen, Saskia C, Houweling, Martin, Helms, J Bernd, Westendorp, Bart, de Bruin, Alain, Cell Biology, Metabolism and Cancer, Pathobiologie, CS_Locomotion, Veterinaire biochemie, Equine Musculoskeletal Biology, Dep Biomolecular Health Sciences
Publikováno v:
Liver International, 42(11), 2442-2452. Wiley
Liver International, 42(11), 2442. Blackwell Publishing Ltd
Liver International, 42(11), 2442. Blackwell Publishing Ltd
The tumour suppressor PTEN is a negative regulator of the PI3K/AKT signalling pathway. Liver-specific deletion of Pten in mice results in the hyper-activation PI3K/AKT signalling accompanied by enhanced genome duplication (polyploidization), marked l
Autor:
Segeren, Hendrika A, van Liere, Elsbeth A, Riemers, Frank M, de Bruin, Alain, Westendorp, Bart, Pathobiologie, dPB RMSC, Chirurgie, dCSCA RMSC-1, Dep Biomolecular Health Sciences, CS_Locomotion
Publikováno v:
Oncogene, 41(19), 2719. Nature Publishing Group
ONCOGENE, 41(19), 2719-2733. Nature Publishing Group
ONCOGENE, 41(19), 2719-2733. Nature Publishing Group
Cancer cells often experience high basal levels of DNA replication stress (RS), for example due to hyperactivation of oncoproteins like MYC or RAS. Therefore, cancer cells are considered to be sensitive to drugs that exacerbate the level of RS or blo
Autor:
Roukens, M Guy, Frederiks, Cynthia L, Seinstra, Danielle, Braccioli, Luca, Khalil, Antoine A, Pals, Cornelieke, De Neck, Simon, Bornes, Laura, Beerling, Evelyne, Mokry, Michal, de Bruin, Alain, Westendorp, Bart, van Rheenen, Jacco, Coffer, Paul J, Pathobiologie DMPC, dPB CR, Dep Biomolecular Health Sciences, Pathobiologie, dPB RMSC
Publikováno v:
Oncogene, 40(45), 6343. Nature Publishing Group
ONCOGENE, 40(45), 6343-6353. Nature Publishing Group
Oncogene
ONCOGENE, 40(45), 6343-6353. Nature Publishing Group
Oncogene
In breast cancer the transcription factor SOX4 has been shown to be associated with poor survival, increased tumor size and metastasis formation. This has mostly been attributed to the ability of SOX4 to regulate Epithelial-to-Mesenchymal-Transition
Autor:
Wierenga, Kathryn A, Riemers, Frank M, Westendorp, Bart, Harkema, Jack R, Pestka, James J, Chirurgie, CS_Locomotion, Pathobiologie
Publikováno v:
Frontiers in Immunology, 13. Frontiers Media S.A.
Preclinical and clinical studies suggest that consumption of long chain omega-3 polyunsaturated fatty acids (PUFAs) reduces severity of chronic inflammatory and autoimmune diseases. While these ameliorative effects are conventionally associated with
Akademický článek
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Autor:
Segeren, Hendrika A., van Rijnberk, Lotte M., Moreno, Eva, Riemers, Frank M., van Liere, Elsbeth A., Yuan, Ruixue, Wubbolts, Richard, de Bruin, Alain, Westendorp, Bart, Pathobiologie, dPB RMSC, Chirurgie, dCSCA RMSC-1, LS Pathobiologie, IOV CCB, Celbiologie, dB&C I&I, Dep Biomolecular Health Sciences, CS_Locomotion
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108449-(2020)
Cell reports, 33(9):108449, 1-20. CELL PRESS
Cell Reports, 33(9). Elsevier Saunders
Cell reports, 33(9):108449, 1-20. CELL PRESS
Cell Reports, 33(9). Elsevier Saunders
Summary: E2F transcription factors control the expression of cell-cycle genes. Cancers often demonstrate enhanced E2F target gene expression, which can be explained by increased percentages of replicating cells. However, we demonstrate in human cance