Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α.

Autor: West PK; School of Life and Environmental Sciences, Charles Perkins Centre and the Sydney Institute for Infectious Diseases, The University of Sydney, Sydney, NSW, Australia., Viengkhou B; School of Life and Environmental Sciences, Charles Perkins Centre and the Sydney Institute for Infectious Diseases, The University of Sydney, Sydney, NSW, Australia., Campbell IL; School of Life and Environmental Sciences, Charles Perkins Centre and the Sydney Institute for Infectious Diseases, The University of Sydney, Sydney, NSW, Australia., Hofer MJ; School of Life and Environmental Sciences, Charles Perkins Centre and the Sydney Institute for Infectious Diseases, The University of Sydney, Sydney, NSW, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Oct 28; Vol. 13, pp. 1036799. Date of Electronic Publication: 2022 Oct 28 (Print Publication: 2022).

New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis.

Autor: Theunissen F; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia. frances.theunissen@perron.uwa.edu.au.; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA, Australia. frances.theunissen@perron.uwa.edu.au., West PK; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia., Brennan S; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia., Petrović B; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia.; Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, the University of Sydney, Camperdown, NSW, Australia., Hooshmand K; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia.; Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, the University of Sydney, Camperdown, NSW, Australia., Akkari PA; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia.; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Murdoch, WA, Australia.; Division of Neurology, Duke University Medical Centre, Duke University, Durham, NC, USA., Keon M; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia. mattk@genieus.co., Guennewig B; GenieUs Genomics Pty Ltd, Sydney, NSW, Australia.; Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, the University of Sydney, Camperdown, NSW, Australia.

Publikováno v: Translational neurodegeneration [Transl Neurodegener] 2021 Nov 15; Vol. 10 (1), pp. 46. Date of Electronic Publication: 2021 Nov 15.

Contribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infection.

Autor: Jung SR; School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia.; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia., Ashhurst TM; Sydney Cytometry Core Facility, The University of Sydney and Centenary Institute, Sydney, Australia.; Department of Pathology, School of Medical Sciences, Sydney Medical School, The University of Sydney, Sydney, Australia., West PK; School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia.; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia., Viengkhou B; School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia.; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia., King NJC; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia.; Sydney Cytometry Core Facility, The University of Sydney and Centenary Institute, Sydney, Australia.; Department of Pathology, School of Medical Sciences, Sydney Medical School, The University of Sydney, Sydney, Australia., Campbell IL; School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia.; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia., Hofer MJ; School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia.; The Marie Bashir Institute for Infectious Diseases and Biosecurity, the Charles Perkins Centre and the Bosch Institute, The University of Sydney, Sydney, Australia.

Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Apr 20; Vol. 16 (4), pp. e1008525. Date of Electronic Publication: 2020 Apr 20 (Print Publication: 2020).

Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells.

Autor: Hayashida E; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia., Ling ZL; Discipline of Pathology, the Marie Bashir Institute for Infectious Diseases and Biosecurity, the Bosch Institute, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Ashhurst TM; Discipline of Pathology, the Marie Bashir Institute for Infectious Diseases and Biosecurity, the Bosch Institute, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Sydney Cytometry Facility, The University of Sydney and the Centenary Institute, Sydney, Australia., Viengkhou B; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia., Jung SR; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia., Songkhunawej P; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia., West PK; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia., King NJC; Discipline of Pathology, the Marie Bashir Institute for Infectious Diseases and Biosecurity, the Bosch Institute, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Sydney Cytometry Facility, The University of Sydney and the Centenary Institute, Sydney, Australia., Hofer MJ; School of Life and Environmental Sciences, the Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, and the Bosch Institute, The University of Sydney, Sydney, Australia. markus.hofer@sydney.edu.au.; School of Life and Environmental Sciences, The University of Sydney, Molecular Bioscience Bldg., Maze Crescent G08, Sydney, NSW, 2006, Australia. markus.hofer@sydney.edu.au.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2019 Sep 11; Vol. 16 (1), pp. 177. Date of Electronic Publication: 2019 Sep 11.

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Autor: Bensellam M; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia., Maxwell EL; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia., Chan JY; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia., Luzuriaga J; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia., West PK; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia., Jonas JC; Université catholique de Louvain, Institut de recherche expérimentale et clinique, Pôle d'endocrinologie, diabète et nutrition, Brussels, Belgium., Gunton JE; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia.; Westmead Hospital, Sydney, NSW, Australia.; The Westmead Millennium Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia., Laybutt DR; Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia. r.laybutt@garvan.org.au.

Publikováno v: Diabetologia [Diabetologia] 2016 Jul; Vol. 59 (7), pp. 1492-1502. Date of Electronic Publication: 2016 Apr 04.