Differential Accumulation of Misfolded Prion Strains in Natural Hosts of Prion Diseases.

Autor: Lambert ZJ; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, 1800 Christensen, Ames, IA 50011, USA.; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Ave., Ames, IA 50010, USA.; Oak Ridge Institute for Science and Education, 1299 Bethel Valley Rd., Oak Ridge, TN 37830, USA., Greenlee JJ; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Ave., Ames, IA 50010, USA., Cassmann ED; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Ave., Ames, IA 50010, USA., West Greenlee MH; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, 1800 Christensen, Ames, IA 50011, USA.

Publikováno v: Viruses [Viruses] 2021 Dec 07; Vol. 13 (12). Date of Electronic Publication: 2021 Dec 07.

Experimental Study Using Multiple Strains of Prion Disease in Cattle Reveals an Inverse Relationship between Incubation Time and Misfolded Prion Accumulation, Neuroinflammation, and Autophagy.

Autor: Mammadova N; Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa; Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa., West Greenlee MH; Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa. Electronic address: mheather@iastate.edu., Moore SJ; Virus and Prion Research Unit, National Animal Disease Center, US Department of Agriculture, Agricultural Research Service, Ames, Iowa., Sakaguchi DS; Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa., Greenlee JJ; Virus and Prion Research Unit, National Animal Disease Center, US Department of Agriculture, Agricultural Research Service, Ames, Iowa.

Publikováno v: The American journal of pathology [Am J Pathol] 2020 Jul; Vol. 190 (7), pp. 1461-1473. Date of Electronic Publication: 2020 Apr 04.

Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein.

Autor: Moore J; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA., Tatum T; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA., Hwang S; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA., Vrentas C; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA., West Greenlee MH; Iowa State University, Department of Biomedical Sciences, Ames, 50010, USA., Kong Q; Case Western Reserve University, Departments of Pathology and Neurology, Cleveland, 44106, USA., Nicholson E; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA., Greenlee J; USDA, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, 50010, USA. justin.greenlee@usda.gov.

Publikováno v: Scientific reports [Sci Rep] 2020 Feb 21; Vol. 10 (1), pp. 3148. Date of Electronic Publication: 2020 Feb 21.

Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer.

Autor: Hwang S; United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, United States., West Greenlee MH; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, United States., Balkema-Buschmann A; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., Groschup MH; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., Nicholson EM; United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, United States., Greenlee JJ; United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, United States.

Publikováno v: Frontiers in veterinary science [Front Vet Sci] 2018 Jan 19; Vol. 4, pp. 242. Date of Electronic Publication: 2018 Jan 19 (Print Publication: 2017).

Lasting Retinal Injury in a Mouse Model of Blast-Induced Trauma.

Autor: Mammadova N; Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa; Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa., Ghaisas S; Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa., Zenitsky G; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa., Sakaguchi DS; Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa., Kanthasamy AG; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa., Greenlee JJ; Virus and Prion Research Unit, National Animal Disease Center, US Department of Agriculture, Agricultural Research Service, Ames, Iowa., West Greenlee MH; Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa. Electronic address: mheather@iastate.edu.

Publikováno v: The American journal of pathology [Am J Pathol] 2017 Jul; Vol. 187 (7), pp. 1459-1472. Date of Electronic Publication: 2017 Jun 09.