Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

Autor: Sambucetti Lidia C, Zhu Lingyun, Ahsan Muhammad H, Zhang Ning, Purchio Anthony F, West David B

Publikováno v: Journal of Inflammation, Vol 2, Iss 1, p 10 (2005)

Abstract IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this sig

Externí odkaz: https://doaj.org/article/4c54c7259ee64b97875ad65991d2c1f3

In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs

Autor: Davies, Stephen J., Smith, Steven J., Lim, K.C., Zhang, Hongbing, Purchio, Anthony F., McKerrow, James H., West, David B.

Publikováno v: In International Journal for Parasitology 2005 35(8):851-859

Corrigendum: High-throughput discovery of novel developmental phenotypes

Autor: Dickinson, Mary E, Flenniken, Ann M, Ji, Xiao, Teboul, Lydia, Wong, Michael D, White, Jacqueline K, Meehan, Terrence F, Weninger, Wolfgang J, Westerberg, Henrik, Adissu, Hibret, Baker, Candice N, Bower, Lynette, Brown, James M, Caddle, L Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J, Denegre, James M, Doe, Brendan, Dolan, Mary E, Edie Helmut Fuchs, Sarah M, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R, Hsu, Chih-Wei, Johnson, Sara J, Kalaga, Sowmya, Keith, Lance C, Lanoue, Louise, Lawson, Thomas N, Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L, Nutter, Susan Newbigging Lauryl MJ, Peterson, Kevin A, Ramirez-Solis, Ramiro, Rowland, Douglas J, Ryder, Edward, Samocha, Kaitlin E, Seavitt, John R, Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B, Wong, Leeyean, Yoshiki, Atsushi, International Mouse Phenotyping Consortium, Wurst, Wolfgang, MacArthur, Daniel G, Tocchini-Valentini, Glauco P, Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C, Justice, Monica J, Parkinson, Helen E, Moore, Mark, Wells, Sara, Braun, Robert E, Svenson, Karen L, de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R Mark, Brown, Steve DM, Adams, David J, Lloyd, KC Kent, McKerlie, Colin, Beaudet, Arthur L, Murray, Maja Bućan Stephen A

Publikováno v: Nature, vol 551, iss 7680

This corrects the article DOI: 10.1038/nature19356.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::32fcd8b4adc5cb08e911c01c01c8f19b
https://escholarship.org/uc/item/21m2349q

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Autor: Bowl, Michael R., Simon, Michelle M., Ingham, Neil J., Greenaway, Simon, Santos, Luis, Cater, Heather, Taylor, Sarah, Mason, Jeremy, Kurbatova, Natalja, Pearson, Selina, Bower, Lynette R., Clary, Dave A., Meziane, Hamid, Reilly, Patrick, Minowa, Osamu, Kelsey, Lois, Allen, Sue, Clementson-Mobbs, Sharon, Codner, Gemma, Fray, Martin, Gardiner, Wendy, Joynson, Russell, Kenyon, Janet, Loeffler, Jorik, Nell, Barbara, Parker, Andrew, Quwailid, Deen, Stewart, Michelle, Walling, Alison, Zaman, Rumana, Chen, Chao Kung, Conte, Nathalie, Matthews, Peter, Relac, Mike, Tudose, Ilinca, Warren, Jonathan, Le Marchand, Elise, El Amri, Amal, El Fertak, Leila, Ennah, Hamid, Ali-Hadji, Dalila, Ayadi, Abdel, Wattenhofer-Donze, Marie, Moulaert, David, Jacquot, Sylvie, André, Philippe, Birling, Marie Christine, Pavlovic, Guillaume, Lalanne, Valérie, Lux, Aline, Riet, Fabrice, Mittelhaeuser, Christophe, Bour, Raphael, Guimond, Alain, Bam'Hamed, Chaouki, Leblanc, Sophie, Vasseur, Laurent, Selloum, Mohammed, Sorg, Tania, Ayabe, Shinya, Furuse, Tamio, Kaneda, Hideki, Kobayashi, Kimio, Masuya, Hiroshi, Miura, Ikuo, Obata, Yuichi, Suzuki, Tomohiro, Tamura, Masaru, Tanaka, Nobuhiko, Yamada, Ikuko, Yoshiki, Atsushi, Berberovic, Zorana, Bubshait, Mohammed, Cabezas, Jorge, Carroll, Tracy, Clark, Greg, Clarke, Shannon, Creighton, Amie, Danisment, Ozge, Eskandarian, Mohammad, Feugas, Patricia, Gertsenstein, Marina, Guo, Ruolin, Hunter, Jane, Jacob, Elsa, Lan, Qing, Laurin, Valerie, Law, Napoleon, MacMaster, Sue, Miller, David, Morikawa, Lily, Newbigging, Susan, Owen, Celeste, Penton, Patricia, Pereira, Monica, Qu, Dawei, Shang, Xueyuan, Sleep, Gillian, Sohel, Khondoker, Tondat, Sandra, Wang, Yanchun, Vukobradovic, Igor, Zhu, Yingchun, Chiani, Francesco, Di Pietro, Chiara, Di Segni, Gianfranco, Ermakova, Olga, Ferrara, Filomena, Fruscoloni, Paolo, Gambadoro, Aalessia, Gastaldi, Serena, Golini, Elisabetta, Sala, Gina La, Mandillo, Silvia, Marazziti, Daniela, Massimi, Marzia, Matteoni, Rafaele, Orsini, Tiziana, Pasquini, Miriam, Raspa, Marcello, Rauch, Aline, Rossi, Gianfranco, Rossi, Nicoletta, Putti, Sabrina, Scavizzi, Ferdinando, Tocchini-Valentini, Giuseppe D., Beig, Joachim, Bürger, Antje, Giesert, Florian, Graw, Jochen, Kühn, Ralf, Oritz, Oskar, Schick, Joel, Seisenberger, Claudia, Amarie, Oana, Garrett, Lillian, Hölter, Sabine M., Zimprich, Annemarie, Aguilar-Pimentel, Antonio, Beckers, Johannes, Brommage, Robert, Calzada-Wack, Julia, Fuchs, Helmut, Gailus-Durner, Valérie, Lengger, Christoph, Leuchtenberger, Stefanie, Maier, Holger, Marschall, Susan, Moreth, Kristin, Neff, Frauke, Östereicher, Manuela A., Rozman, Jan, Steinkamp, Ralph, Stoeger, Claudia, Treise, Irina, Stoeger, Tobias, Yildrim, Ali Önder, Eickelberg, Oliver, Becker, Lore, Klopstock, Thomas, Ollert, Markus, Busch, Dirk H., Schmidt-Weber, Carsten, Bekeredjian, Raffi, Zimmer, Andreas, Rathkolb, Birgit, Wolf, Eckhard, Klingenspor, Martin, Tocchini-Valentini, Glauco P., Gao, Xiang, Bradley, Allan, Skarnes, William C., Moore, Mark, Beaudet, Arthur L., Justice, Monica J., Seavitt, John, Dickinson, Mary E., Wurst, Wolfgang, De Angelis, Martin Hrabe, Herault, Yann, Wakana, Shigeharu, Nutter, Lauryl M.J., Flenniken, Ann M., McKerlie, Colin, Murray, Stephen A., Svenson, Karen L., Braun, Robert E., West, David B., Lloyd, K. C.Kent, Adams, David J., White, Jacqui, Karp, Natasha, Flicek, Paul, Smedley, Damian, Meehan, Terrence F., Parkinson, Helen E., Teboul, Lydia M., Wells, Sara, Steel, Karen P., Mallon, Ann Marie, Brown, Steve D.M.

Publikováno v: Nat. Commun. 8:886 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Bowl, M R, Simon, M M, Ingham, N J, Greenaway, S, Santos, L, Cater, H, Taylor, S, Mason, J, Kurbatova, N, Pearson, S, Bower, L R, Clary, D A, Meziane, H, Reilly, P, Minowa, O, Kelsey, L, Allen, S, Clementson-Mobbs, S, Codner, G, Fray, M, Gardiner, W, Joynson, R, Kenyon, J, Loeffler, J, Nell, B, Parker, A, Quwailid, D, Stewart, M, Walling, A, Zaman, R, Chen, C K, Conte, N, Matthews, P, Relac, M, Tudose, I, Warren, J, Le Marchand, E, El Amri, A, El Fertak, L, Ennah, H, Ali-Hadji, D, Ayadi, A, Wattenhofer-Donze, M, Moulaert, D, Jacquot, S, André, P, Birling, M C, Pavlovic, G, Lalanne, V, Lux, A, Riet, F, Mittelhaeuser, C, Bour, R, Guimond, A, Bam'Hamed, C, Leblanc, S, Vasseur, L, Selloum, M, Sorg, T, Ayabe, S, Furuse, T, Kaneda, H, Kobayashi, K, Masuya, H, Miura, I, Obata, Y, Suzuki, T, Tamura, M, Tanaka, N, Yamada, I, Yoshiki, A, Berberovic, Z, Bubshait, M, Cabezas, J, Carroll, T, Clark, G, Clarke, S, Creighton, A, Danisment, O, Eskandarian, M, Feugas, P, Gertsenstein, M, Guo, R, Hunter, J, Jacob, E, Lan, Q, Laurin, V, Law, N, MacMaster, S, Miller, D, Morikawa, L, Newbigging, S, Owen, C, Penton, P, Pereira, M, Qu, D, Shang, X, Sleep, G, Sohel, K, Tondat, S, Wang, Y, Vukobradovic, I, Zhu, Y, Chiani, F, Di Pietro, C, Di Segni, G, Ermakova, O, Ferrara, F, Fruscoloni, P, Gambadoro, A, Gastaldi, S, Golini, E, Sala, G L, Mandillo, S, Marazziti, D, Massimi, M, Matteoni, R, Orsini, T, Pasquini, M, Raspa, M, Rauch, A, Rossi, G, Rossi, N, Putti, S, Scavizzi, F, Tocchini-Valentini, G D, Beig, J, Bürger, A, Giesert, F, Graw, J, Kühn, R, Oritz, O, Schick, J, Seisenberger, C, Amarie, O, Garrett, L, Hölter, S M, Zimprich, A, Aguilar-Pimentel, A, Beckers, J, Brommage, R, Calzada-Wack, J, Fuchs, H, Gailus-Durner, V, Lengger, C, Leuchtenberger, S, Maier, H, Marschall, S, Moreth, K, Neff, F, Östereicher, M A, Rozman, J, Steinkamp, R, Stoeger, C, Treise, I, Stoeger, T, Yildrim, A Ö, Eickelberg, O, Becker, L, Klopstock, T, Ollert, M, Busch, D H, Schmidt-Weber, C, Bekeredjian, R, Zimmer, A, Rathkolb, B, Wolf, E, Klingenspor, M, Tocchini-Valentini, G P, Gao, X, Bradley, A, Skarnes, W C, Moore, M, Beaudet, A L, Justice, M J, Seavitt, J, Dickinson, M E, Wurst, W, De Angelis, M H, Herault, Y, Wakana, S, Nutter, L M J, Flenniken, A M, McKerlie, C, Murray, S A, Svenson, K L, Braun, R E, West, D B, Lloyd, K C K, Adams, D J, White, J, Karp, N, Flicek, P, Smedley, D, Meehan, T F, Parkinson, H E, Teboul, L M, Wells, S, Steel, K P, Mallon, A M & Brown, S D M 2017, ' A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction ', Nature Communications, vol. 8, 886 . https://doi.org/10.1038/s41467-017-00595-4
Nature communications, vol 8, iss 1

The developmental and physiological complexity of the auditory system is likely reflected in the underlying set of genes involved in auditory function. In humans, over 150 non-syndromic loci have been identified, and there are more than 400 human gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77ae2af84f093286e7804c4a997406
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=52089

High-throughput discovery of novel developmental phenotypes

Autor: Dickinson, Mary E, Flenniken, Ann M, Ji, Xiao, Teboul, Lydia, Wong, Michael D, White, Jacqueline K, Meehan, Terrence F, Weninger, Wolfgang J, Westerberg, Henrik, Adissu, Hibret, Baker, Candice N, Bower, Lynette, Brown, James M, Caddle, L Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J, Denegre, James M, Doe, Brendan, Dolan, Mary E, Edie, Sarah M, Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R, Hsu, Chih-Wei, Johnson, Sara J, Kalaga, Sowmya, Keith, Lance C, Lanoue, Louise, Lawson, Thomas N, Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L, Newbigging, Susan, Nutter, Lauryl MJ, Peterson, Kevin A, Ramirez-Solis, Ramiro, Rowland, Douglas J, Ryder, Edward, Samocha, Kaitlin E, Seavitt, John R, Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B, Wong, Leeyean, Yoshiki, Atsushi, International Mouse Phenotyping Consortium, Laboratory, Jackson, Infrastructure Nationale PHENOMIN, Institut Clinique De La Souris (ICS), Laboratories, Charles River, MRC Harwell, Toronto Centre For Phenogenomics, Wellcome Trust Sanger Institute, RIKEN BioResource Center, MacArthur, Daniel G, Tocchini-Valentini, Glauco P, Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C, Justice, Monica J, Parkinson, Helen E, Moore, Mark, Wells, Sara, Braun, Robert E, Svenson, Karen L, De Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R Mark, Brown, Steve DM, Adams, David J, Lloyd, KC Kent, McKerlie, Colin, Beaudet, Arthur L, Bućan, Maja, Murray, Stephen A

Publikováno v: Nature, vol 537, iss 7621

Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous insight into gene function and congenital disorders. As part of the International Mouse Phenoty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169e416fc7325a32ddbee0ebd8424d03
https://escholarship.org/uc/item/06t772m3