Zobrazeno 1 - 10 of 1 878 pro vyhledávání: '"West, NR"'
2
Akademický článek
The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity.
Autor: Lim J; Genentech Inc., South San Francisco, California., Rodriguez R; Genentech Inc., South San Francisco, California., Williams K; Genentech Inc., South San Francisco, California., Silva J; Genentech Inc., South San Francisco, California., Gutierrez AG; Genentech Inc., South San Francisco, California., Tyler P; Genentech Inc., South San Francisco, California., Baharom F; Genentech Inc., South San Francisco, California., Sun T; Genentech Inc., South San Francisco, California., Lin E; Genentech Inc., South San Francisco, California., Martin S; Genentech Inc., South San Francisco, California., Kayser BD; Genentech Inc., South San Francisco, California., Johnston RJ; Genentech Inc., South San Francisco, California., Mellman I; Genentech Inc., South San Francisco, California., Delamarre L; Genentech Inc., South San Francisco, California., West NR; Genentech Inc., South San Francisco, California., Müller S; Genentech Inc., South San Francisco, California., Qu Y; Genentech Inc., South San Francisco, California., Heger K; Genentech Inc., South San Francisco, California.
Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Jun 04; Vol. 12 (6), pp. 663-672.
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3
Akademický článek
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer.
Autor: Taraborrelli L; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA., Şenbabaoğlu Y; Department of Oncology Bioinformatics, Genentech Inc., South San Francisco, USA., Wang L; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA., Lim J; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA., Blake K; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA., Kljavin N; Department of Molecular Oncology, Genentech Inc., South San Francisco, USA., Gierke S; Center for Advanced Light Microscopy, Genentech Inc., South San Francisco, USA.; Department of Pathology, Genentech Inc., South San Francisco, USA., Scherl A; Department of Pathology, Genentech Inc., South San Francisco, USA., Ziai J; Department of Pathology, Genentech Inc., South San Francisco, USA., McNamara E; Department of In Vivo Pharmacology, Genentech Inc., South San Francisco, USA., Owyong M; Department of In Vivo Pharmacology, Genentech Inc., South San Francisco, USA., Rao S; Department of Oncology Bioinformatics, Genentech Inc., South San Francisco, USA., Calviello AK; Department of Oncology Bioinformatics, Genentech Inc., South San Francisco, USA., Oreper D; Department of Oncology Bioinformatics, Genentech Inc., South San Francisco, USA., Jhunjhunwala S; Department of Oncology Bioinformatics, Genentech Inc., South San Francisco, USA., Argiles G; Vall d'Hebrón Institute of Oncology, Vall d'Hebrón University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain., Bendell J; Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN, USA., Kim TW; Department of Oncology, Medical Center, University of Ulsan, Seoul, Korea., Ciardiello F; Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy., Wongchenko MJ; Oncology Biomarker Development, Genentech, Inc., South San Francisco, CA, USA., de Sauvage FJ; Department of Molecular Oncology, Genentech Inc., South San Francisco, USA., de Sousa E Melo F; Department of Discovery Oncology, Genentech Inc., South San Francisco, USA., Yan Y; Oncology Biomarker Development, Genentech, Inc., South San Francisco, CA, USA., West NR; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA. west.nathaniel@gene.com., Murthy A; Department of Cancer Immunology, Genentech Inc., South San Francisco, USA. aditya.murthy@gilead.com.; Gilead Sciences, Foster City, USA. aditya.murthy@gilead.com.
Publikováno v: Nature communications [Nat Commun] 2023 Sep 23; Vol. 14 (1), pp. 5945. Date of Electronic Publication: 2023 Sep 23.
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4
Akademický článek
CD8 + T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy.
Autor: Huseni MA; Genentech, South San Francisco, CA 94080, USA. Electronic address: huseni.mahrukh@gene.com., Wang L; Genentech, South San Francisco, CA 94080, USA., Klementowicz JE; Genentech, South San Francisco, CA 94080, USA., Yuen K; Genentech, South San Francisco, CA 94080, USA., Breart B; Genentech, South San Francisco, CA 94080, USA., Orr C; Genentech, South San Francisco, CA 94080, USA., Liu LF; Genentech, South San Francisco, CA 94080, USA., Li Y; Genentech, South San Francisco, CA 94080, USA., Gupta V; Genentech, South San Francisco, CA 94080, USA., Li C; Genentech, South San Francisco, CA 94080, USA., Rishipathak D; Genentech, South San Francisco, CA 94080, USA., Peng J; Genentech, South San Francisco, CA 94080, USA., Şenbabaoǧlu Y; Genentech, South San Francisco, CA 94080, USA., Modrusan Z; Genentech, South San Francisco, CA 94080, USA., Keerthivasan S; Genentech, South San Francisco, CA 94080, USA., Madireddi S; Genentech, South San Francisco, CA 94080, USA., Chen YJ; Genentech, South San Francisco, CA 94080, USA., Fraser EJ; Genentech, South San Francisco, CA 94080, USA., Leng N; Genentech, South San Francisco, CA 94080, USA., Hamidi H; Genentech, South San Francisco, CA 94080, USA., Koeppen H; Genentech, South San Francisco, CA 94080, USA., Ziai J; Genentech, South San Francisco, CA 94080, USA., Hashimoto K; Genentech, South San Francisco, CA 94080, USA., Fassò M; Genentech, South San Francisco, CA 94080, USA., Williams P; Genentech, South San Francisco, CA 94080, USA., McDermott DF; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Rosenberg JE; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Powles T; Barts Experimental Cancer Medicine Centre, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK., Emens LA; University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, PA 15213, USA., Hegde PS; Genentech, South San Francisco, CA 94080, USA., Mellman I; Genentech, South San Francisco, CA 94080, USA., Turley SJ; Genentech, South San Francisco, CA 94080, USA., Wilson MS; Genentech, South San Francisco, CA 94080, USA., Mariathasan S; Genentech, South San Francisco, CA 94080, USA., Molinero L; Genentech, South San Francisco, CA 94080, USA., Merchant M; Genentech, South San Francisco, CA 94080, USA., West NR; Genentech, South San Francisco, CA 94080, USA. Electronic address: west.nathaniel@gene.com.
Publikováno v: Cell reports. Medicine [Cell Rep Med] 2023 Jan 17; Vol. 4 (1), pp. 100878. Date of Electronic Publication: 2023 Jan 03.
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6
Akademický článek
Cell models for Down syndrome-Alzheimer's disease research.
Autor: Wu Y; U.K. Dementia Research Institute, Institute of Neurology, University College London, London, U.K., West NR; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI 53705, U.S.A.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, U.S.A., Bhattacharyya A; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, U.S.A.; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, U.S.A., Wiseman FK; U.K. Dementia Research Institute, Institute of Neurology, University College London, London, U.K.; LonDownS Consortium, London, U.K.
Publikováno v: Neuronal signaling [Neuronal Signal] 2022 Apr 08; Vol. 6 (1), pp. NS20210054. Date of Electronic Publication: 2022 Apr 08 (Print Publication: 2022).
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7
Akademický článek
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Autor: Headland SE; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Dengler HS; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Xu D; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Teng G; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Everett C; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA 94080, USA., Ratsimandresy RA; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Yan D; Translational Immunology, Genentech Inc., South San Francisco, CA 94080, USA., Kang J; Translational Immunology, Genentech Inc., South San Francisco, CA 94080, USA., Ganeshan K; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Nazarova EV; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Gierke S; Center for Advanced Light Microscopy, Genentech Inc., South San Francisco, CA 94080, USA.; Pathology, Genentech Inc., South San Francisco, CA 94080, USA., Wedeles CJ; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Guidi R; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., DePianto DJ; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Morshead KB; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Huynh A; Necropsy, Genentech Inc., South San Francisco, CA 94080, USA., Mills J; Necropsy, Genentech Inc., South San Francisco, CA 94080, USA., Flanagan S; Necropsy, Genentech Inc., South San Francisco, CA 94080, USA., Hambro S; Necropsy, Genentech Inc., South San Francisco, CA 94080, USA., Nunez V; Necropsy, Genentech Inc., South San Francisco, CA 94080, USA., Klementowicz JE; Cancer Immunology Discovery, Genentech Inc., South San Francisco, CA 94080, USA., Shi Y; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA 94080, USA., Wang J; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA 94080, USA., Bevers J 3rd; Antibody Discovery, Genentech Inc., South San Francisco, CA 94080, USA., Ramirez-Carrozzi V; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Pappu R; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Abbas A; OMNI Bioinformatics, Genentech Inc., South San Francisco, CA 94080, USA., Vander Heiden J; OMNI Bioinformatics, Genentech Inc., South San Francisco, CA 94080, USA., Choy DF; Biomarker Discovery OMNI, Genentech Inc., South San Francisco, CA 94080, USA., Yadav R; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., South San Francisco, CA 94080, USA., Modrusan Z; Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA., Panettieri RA Jr; Rutgers Institute for Translational Medicine and Science, State University of New Jersey, New Brunswick, NJ 08901, USA., Koziol-White C; Rutgers Institute for Translational Medicine and Science, State University of New Jersey, New Brunswick, NJ 08901, USA., Jester WF Jr; Rutgers Institute for Translational Medicine and Science, State University of New Jersey, New Brunswick, NJ 08901, USA., Jenkins BJ; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia.; Department of Molecular Translational Science, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Clayton, Victoria 3800, Australia., Cao Y; OMNI Bioinformatics, Genentech Inc., South San Francisco, CA 94080, USA., Clarke C; OMNI Bioinformatics, Genentech Inc., South San Francisco, CA 94080, USA., Austin C; Pathology, Genentech Inc., South San Francisco, CA 94080, USA., Lafkas D; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., Xu M; Translational Immunology, Genentech Inc., South San Francisco, CA 94080, USA., Wolters PJ; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94110, USA., Arron JR; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA., West NR; Cancer Immunology Discovery, Genentech Inc., South San Francisco, CA 94080, USA., Wilson MS; Immunology Discovery,Genentech Inc., South San Francisco, CA 94080, USA.
Publikováno v: Science translational medicine [Sci Transl Med] 2022 Jan 12; Vol. 14 (627), pp. eabf8188. Date of Electronic Publication: 2022 Jan 12.
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Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation
Autor: Hegazy, AN, West, NR, Stubbington, MJT, Wendt, E, Suijker, KIM, Datsi, A, This, S, Danne, C, Campion, S, Duncan, SH, Owens, BMJ, Uhlig, HH, McMichael, A, Bergthaler, A, Teichmann, SA, Keshav, S, Powrie, F
Publikováno v: Gastroenterology. 153(5)
Background & Aims Interactions between commensal microbes and the immune system are tightly regulated and maintain intestinal homeostasis, but little is known about these interactions in humans. We investigated responses of human CD4+T cellsto the in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::77be831271cfce0610d56bfe5fb495bf
http://ora.ox.ac.uk/objects/uuid:
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9
Corrigendum: Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease.
Autor: Martinez JL; Cellular and Molecular Biology Graduate Program, University of Wisconsin, Madison, WI, United States.; Waisman Center, University of Wisconsin, Madison, WI, United States., Zammit MD; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States., West NR; Cellular and Molecular Biology Graduate Program, University of Wisconsin, Madison, WI, United States.; Waisman Center, University of Wisconsin, Madison, WI, United States., Christian BT; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.; Department of Psychiatry, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States., Bhattacharyya A; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Cellular and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.
Publikováno v: Frontiers in aging neuroscience [Front Aging Neurosci] 2021 Aug 05; Vol. 13, pp. 742233. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).
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10
Akademický článek
Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease.
Autor: Martinez JL; Cellular and Molecular Biology Graduate Program, University of Wisconsin, Madison, WI, United States.; Waisman Center, University of Wisconsin, Madison, WI, United States., Zammit MD; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States., West NR; Cellular and Molecular Biology Graduate Program, University of Wisconsin, Madison, WI, United States.; Waisman Center, University of Wisconsin, Madison, WI, United States., Christian BT; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.; Department of Psychiatry, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States., Bhattacharyya A; Waisman Center, University of Wisconsin, Madison, WI, United States.; Department of Cellular and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.
Publikováno v: Frontiers in aging neuroscience [Front Aging Neurosci] 2021 Jul 12; Vol. 13, pp. 703876. Date of Electronic Publication: 2021 Jul 12 (Print Publication: 2021).
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