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The RU486-dependent activation of the GeneSwitch system in adult muscles leads to severe adverse effects in Drosophila.

Autor: Zappia MP; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA., Damschroder D; Department of Physiology, Wayne State School of Medicine, Detroit, MI 48201, USA., Westacott A; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA., Wessells RJ; Department of Physiology, Wayne State School of Medicine, Detroit, MI 48201, USA., Frolov MV; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA.

Publikováno v: G3 (Bethesda, Md.) [G3 (Bethesda)] 2024 May 07; Vol. 14 (5).

Iditarod , a Drosophila homolog of the Irisin precursor FNDC5 , is critical for exercise performance and cardiac autophagy.

Autor: Cobb T; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201., Hwang I; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109., Soukar M; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109., Namkoong S; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea., Cho US; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109., Safdar M; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201., Kim M; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109., Wessells RJ; Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201., Lee JH; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Sep 26; Vol. 120 (39), pp. e2220556120. Date of Electronic Publication: 2023 Sep 18.

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias.

Autor: Sujkowski A; Department of Physiology, Wayne State University School of Medicine, Detroit, United States.; Department of Pharmacology, Wayne State University School of Medicine, Detroit, United States., Richardson K; Department of Physiology, Wayne State University School of Medicine, Detroit, United States., Prifti MV; Department of Pharmacology, Wayne State University School of Medicine, Detroit, United States., Wessells RJ; Department of Physiology, Wayne State University School of Medicine, Detroit, United States., Todi SV; Department of Pharmacology, Wayne State University School of Medicine, Detroit, United States.; Department of Neurology, Wayne State University School of Medicine, Detroit, United States.

Publikováno v: ELife [Elife] 2022 Feb 16; Vol. 11. Date of Electronic Publication: 2022 Feb 16.