Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wessam, Abdelhady"'
Autor:
Wessam Abdelhady, Nagendra N. Mishra
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Tedizolid (TZD) is an oxazolidinone derivative which demonstrates bacteriostatic activity through inhibition of protein synthesis. We compared the efficacies of TZD and an earlier-generation oxazolidinone, linezolid (LZD), in an experimental murine m
Externí odkaz:
https://doaj.org/article/983104983edc4d39927a3d33677714fe
Autor:
Nagendra N. Mishra, Wessam Abdelhady, Ahmed M. Elsayed, Christian Lapitan, Richard A. Proctor, Michael J. Rybak, Jose M. Miro, Arnold S. Bayer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
The Streptococcus mitis -oralis subgroup of the viridans group streptococci (VGS) are the most common cause of infective endocarditis (IE) in many parts of the world. These organisms are frequently resistant in vitro to standard β-lactams (e.g., pen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f96f775594d4acf0a26f6372f115e0f8
https://doi.org/10.1128/aac.01472-22
https://doi.org/10.1128/aac.01472-22
Autor:
Lou Lu, Arnold S. Bayer, Wessam Abdelhady, Liang Li, Yan Q. Xiong, Jong-In Hong, Niles P. Donegan, Michael R. Yeaman, Ambrose L. Cheung
Publikováno v:
J Infect Dis
Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a significant clinical-therapeutic challenge. Of particular concern is antibiotic treatment failure in infections caused by MRSA that are “susceptible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139235a4476e15b434a9961b1c0a2ce8
https://doi.org/10.1093/infdis/jiaa202
https://doi.org/10.1093/infdis/jiaa202
Autor:
Warren E. Rose, Wessam Abdelhady, Richard A. Proctor, Cassandra Lew, Christian K. Lapitan, Nagendra N. Mishra, Arnold S. Bayer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Increased usage of daptomycin (DAP) for methicillin-resistant Staphylococcus aureus (MRSA) infections has led to emergence of DAP-resistant (DAP-R) strains, resulting in treatment failures. DAP-fosfomycin (Fosfo) combinations are synergistically acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9cf61c3340cad071558355ef9a099a
https://doi.org/10.1128/aac.01649-21
https://doi.org/10.1128/aac.01649-21
Autor:
Nagendra N, Mishra, Cassandra, Lew, Wessam, Abdelhady, Christian K, Lapitan, Richard A, Proctor, Warren E, Rose, Arnold S, Bayer
Publikováno v:
Antimicrob Agents Chemother
Increased usage of daptomycin (DAP) for methicillin-resistant Staphylococcus aureus (MRSA) infections has led to emergence of DAP-resistant (DAP-R) strains, resulting in treatment failures. DAP-fosfomycin (Fosfo) combinations are synergistically acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::976b63f75840445bc7f30219de213048
https://pubmed.ncbi.nlm.nih.gov/34694870
https://pubmed.ncbi.nlm.nih.gov/34694870
Publikováno v:
J Infect Dis
BackgroundMgrA is an important global virulence gene regulator in Staphylococcus aureus. In the present study, the role of mgrA in host-pathogen interactions related to virulence was explored in both methicillin-resistant S. aureus (MRSA) and methici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e4e4c45004a40cbc2dea4ec8ae4295
https://doi.org/10.1093/infdis/jiz219
https://doi.org/10.1093/infdis/jiz219
Autor:
David Huang, Arnold S. Bayer, Yan Q. Xiong, Katyna Borroto-Esoda, Nancy Kerzee, Wessam Abdelhady, Eric Gaukel, Simon Lowry
MRSA endovascular infections are frequently recalcitrant to treatment with standard-of-care antibiotics. Anti-staphylococcal phage lysins represent important candidate adjunctive agents against invasive MRSA infections because of both their microbici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96b53ea0beb27ae4c5993755596d23c
https://doi.org/10.1101/2021.03.12.435219
https://doi.org/10.1101/2021.03.12.435219
Autor:
Cara Cassino, Youngju Pak, Yan Q. Xiong, James Iwaz, Sonia Shah, Dario Lehoux, Arnold S. Bayer, Wessam Abdelhady, Raymond Schuch
Publikováno v:
Antimicrob Agents Chemother
Methicillin-resistant Staphylococcus aureus (MRSA) poses significant therapeutic challenges related to its frequency in clinical infections, innate virulence properties, and propensity for multiantibiotic resistance. MRSA is among the most common cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7864998df91c8d7767742231c6825a
https://pubmed.ncbi.nlm.nih.gov/32340988
https://pubmed.ncbi.nlm.nih.gov/32340988
Autor:
Liang Li, Kati Seidl, Niles P. Donegan, Arnold S. Bayer, Yu-Feng Zhou, Ambrose L. Cheung, Yan Q. Xiong, Michael R. Yeaman, Wessam Abdelhady
Publikováno v:
The Journal of Infectious Diseases. 218:1367-1377
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents an important subset of S. aureus endovascular infections. In this study, we investigated potential genetic mechanisms underlying the persistent outcomes. Compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398b0900f1eb2a238249d642a42eb307
https://doi.org/10.1093/infdis/jiy340
https://doi.org/10.1093/infdis/jiy340
Autor:
Yan Q. Xiong, Karen Sauve, Arnold S. Bayer, Cara Cassino, Raymond Schuch, Wessam Abdelhady, Assaf Raz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Bacteriophage-derived lysins are cell-wall-hydrolytic enzymes that represent a potential new class of antibacterial therapeutics in development to address burgeoning antimicrobial resistance. CF-301, the lead compound in this class, is in clinical de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93f5d36c1a9817bfe36b6464d3bd9b5
https://doi.org/10.1128/aac.02291-18
https://doi.org/10.1128/aac.02291-18