Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wesley W. Han"'
Publikováno v:
Journal of Pharmaceutical Sciences. 66:795-798
The hydrolysis of nitrazepam involves a two-step sequential mechanism. The intermediate is the ring-opened compound resulting from scission of the azomethine bond. The final products are glycine and 2-amino-5-ni-robenzophenone. Recyclization of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5e5eb61289ad177997c35f5bae9760
https://doi.org/10.1002/jps.2600660613
https://doi.org/10.1002/jps.2600660613
Publikováno v:
Journal of Pharmaceutical Sciences. 65:1198-1204
Differential absorbance spectroscopy was successfully used to follow the hydrolysis kinetics of chlordiazepoxide and demoxepam from pH 1 to 11. Loss of the methylamino group from chlordiazepoxide produced demoxepam. Demoxepam degraded by a parallel c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fec49f2fff74650767cae7c3949a1f4
https://doi.org/10.1002/jps.2600650817
https://doi.org/10.1002/jps.2600650817
Publikováno v:
Journal of pharmaceutical sciences. 66(4)
The hydrolysis kinetics of oxazepam and diazepam leading to a benzophenone product and a glycine derivative were quantified from pH 1 to 11. For oxazepam, two intermediates were isolated and identified, indicating a parallel consecutive reaction mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48c6de6f224c747d1c7acd63c49d9f9
https://pubmed.ncbi.nlm.nih.gov/16116
https://pubmed.ncbi.nlm.nih.gov/16116
Publikováno v:
In General Pharmacology 1991 22(6):ix-ix