Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wesley W Wang"'
Autor:
Yu Zhang, Jennifer L Pechal, Carl J Schmidt, Heather R Jordan, Wesley W Wang, M Eric Benbow, Sing-Hoi Sze, Aaron M Tarone
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0213829 (2019)
BackgroundThe postmortem microbiome can provide valuable information to a death investigation and to the human health of the once living. Microbiome sequencing produces, in general, large multi-dimensional datasets that can be difficult to analyze an
Externí odkaz:
https://doaj.org/article/ff0946fda66f4489b22695d90a6e38ef
Autor:
Brianna J. Klein, Jordan T. Feigerle, Jibo Zhang, Christopher C. Ebmeier, Lixin Fan, Rohit K. Singh, Wesley W. Wang, Lauren R. Schmitt, Thomas Lee, Kirk C. Hansen, Wenshe R. Liu, Yun-Xing Wang, Brian D. Strahl, P. Anthony Weil, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here the authors report that the Taf2 and Taf14 subunits of the yeast TFIID complex interact and mediate binding to chromatin. Binding of Taf2 to Taf14 promotes a conformational rearrangement in Taf14, resulting in a release of the linker region for
Externí odkaz:
https://doaj.org/article/effb294868064bf0976b394ca5ad6eec
Autor:
Daniel C. Lazar, Wesley W. Wang, Tzu-Yuan Chiu, Weichao Li, Appaso M. Jadhav, Jacob M. Wozniak, Nathalia Gazaniga, Argyrios N. Theofilopoulos, John R. Teijaro, Christopher G. Parker
SLC15A4 is an endolysosome-resident transporter that is intimately linked with autoinflammation and autoimmunity. Specifically, SLC15A4 is critical for Toll-like receptor (TLR) 7, 8, and 9 as well as the nucleotide-binding oligomerization domain-cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255ca11de4559f904dbeaa87ec184711
https://doi.org/10.1101/2022.10.07.511216
https://doi.org/10.1101/2022.10.07.511216
Autor:
Ge Yu, Wesley W. Wang, Kaci C. Kratch, Yuchen Qiao, Shiqing Xu, Jared S. Morse, Sunshine Z. Leeuwon, Xiaoyan Aria Wang, Wenshe R. Liu
Publikováno v:
J Am Chem Soc
Proteins with a functionalized C-terminus such as a C-terminal thioester are key to the synthesis of larger proteins via expressed protein ligation. They are usually made by recombinant fusion to intein. Although powerful, the intein fusion approach
Autor:
Brianna J. Klein, Jordan T. Feigerle, Jibo Zhang, Christopher C. Ebmeier, Lixin Fan, Rohit K. Singh, Wesley W. Wang, Lauren R. Schmitt, Thomas Lee, Kirk C. Hansen, Wenshe R. Liu, Yun-Xing Wang, Brian D. Strahl, P. Anthony Weil, Tatiana G. Kutateladze
Publikováno v:
Nature communications. 13(1)
The assembly and function of the yeast general transcription factor TFIID complex requires specific contacts between its Taf14 and Taf2 subunits, however, the mechanism underlying these contacts remains unclear. Here, we determined the molecular and
Autor:
Li-Yun Chen, Taylor E. Malone, Appaso M Jadhav, Hayden Anderson, Christopher G. Parker, Wesley W. Wang, Jacob M. Wozniak
Protein acetylation is a central event in orchestrating diverse cellular processes. However, current strategies to investigate protein acetylation in cells are often non-specific or lack temporal and magnitude control. Here, we developed an acetylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078a860592dfbf9849c3acb65ccd1f47
https://doi.org/10.1101/2021.07.27.454011
https://doi.org/10.1101/2021.07.27.454011
Autor:
Tim Thomas, Hidetoshi Kono, Becka M. Warfield, Jacques Côté, Catherine Lachance, Wei Li, Tatiana G. Kutateladze, Yi Zhang, Brianna J. Klein, Brian D. Strahl, Xiaolu Wang, Wesley W. Wang, Wenshe R. Liu, Wenyi Mi, Benjamin A. Garcia, Andrew J. Kueh, Shun Sakuraba, Jie Lyu, Suk Min Jang, Anne K. Voss, Xiaobing Shi, Simone Sidoli, Jiuyang Liu, Krzysztof Krajewski
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Acetylation of histone H3K23 has emerged as an essential posttranslational modification associated with cancer and learning and memory impairment, yet our understanding of this epigenetic mark remains insufficient. Here, we identify the native MORF c
Autor:
Brianna J. Klein, Kendra R. Vann, Forest H. Andrews, Wesley W. Wang, Jibo Zhang, Yi Zhang, Anastasia A. Beloglazkina, Wenyi Mi, Yuanyuan Li, Haitao Li, Xiaobing Shi, Andrei G. Kutateladze, Brian D. Strahl, Wenshe R. Liu, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
The YEATS domain has been identified as a reader of histone acylation and more recently emerged as a promising anti-cancer therapeutic target. Here, we detail the structural mechanisms for π-π-π stacking involving the YEATS domains of yeast Taf14
Publikováno v:
Journal of medicinal chemistry. 63(8)
The transport of materials across membranes is a vital process for all aspects of cellular function, including growth, metabolism, and communication. Protein transporters are the molecular gates that control this movement and serve as key points of r
Autor:
Deb Ranjan Banerjee, Charles E. Deckard, James D. Batteas, Wesley W. Wang, Meagan B. Elinski, Meridith L. Buzbee, Jonathan T. Sczepanski
Publikováno v:
Journal of the American Chemical Society. 140:8260-8267
The genomic DNA of eukaryotic cells exists in the form of chromatin, the structure of which controls the biochemical accessibility of the underlying DNA to effector proteins. In order to gain an in depth molecular understanding of how chromatin struc