Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wesley Seidel"'
Autor:
Wesley Seidel Carvalho
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
O Reconhecimento de Entidades Mencionadas (REM) é uma subtarefa da extração de informações e tem como objetivo localizar e classificar elementos do texto em categorias pré-definidas tais como nome de pessoas, organizações, lugares, datas e ou
Autor:
Carvalho, Wesley Seidel
O Reconhecimento de Entidades Mencionadas (REM) é uma subtarefa da extração de informações e tem como objetivo localizar e classificar elementos do texto em categorias pré-definidas tais como nome de pessoas, organizações, lugares, datas e ou
Autor:
Charles H. Mitch, Aiping Zhang, Mercedes Carpintero, Bradley Condon, C. Groshong, Shane Atwell, John W. Koss, Carl D Overshiner, Jeffrey M. Schkeryantz, Stephon C. Smith, Mark G. Bures, James E. Matt, S.R. Wasserman, Adam M. Fivush, Wesley Seidel, Carlos Jaramillo, K. Conners, David W. Bedwell, Jeffrey M. Witkin, Maria-Jesus Blanco, Daniel Ray Mayhugh, Steven James Quimby, Bruce A. Dressman, Keith A. Wafford, John T. Catlow, Allie Edward Tripp, Paul L. Ornstein, Mario Barberis, José Francisco Soriano, Steven Swanson, Beverly A. Heinz, Jon A. Erickson, Xia Li, Iain MacEwan, Thomas C. Britton, James A. Monn, Susana García-Cerrada, Jing Wang, Mark Donald Chappell, Eric George Tromiczak, Renhua Li, José Eugenio de Diego, Christine Sougias, Tatiana Natali Vetman, Xushan Wang, Stephen Antonysamy
Publikováno v:
Journal of Medicinal Chemistry. 59:10974-10993
As part of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu2/3) receptors, we have incorporated substitution at the C3 and C4 positions of the (1S,2R,5R,6R)-2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812f4203afd8777afc4ec3e0d87f74f0
https://doi.org/10.1021/acs.jmedchem.6b01119
https://doi.org/10.1021/acs.jmedchem.6b01119
Autor:
Bruce A. Dressman, Charles H. Mitch, Mercedes Carpintero, Susana García-Cerrada, John T. Catlow, Tatiana Natali Vetman, Wesley Seidel, Mark Donald Chappell, Jeffrey M. Schkeryantz, Albert Khilevich, Xushan Wang, Allie Edward Tripp, Jeffrey M. Witkin, Maria-Jesus Blanco, Renhua Li, Stephon C. Smith, José Francisco Soriano, Mario Barberis, Steven Swanson, Xia Li, Carlos Jaramillo, Beverly A. Heinz, Thomas C. Britton, Carl D Overshiner, Keith A. Wafford, Eric George Tromiczak, José Eugenio de Diego, James E. Matt, David W. Bedwell, Steven James Quimby, Adam M. Fivush, Paul L. Ornstein
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:5663-5668
Negative modulators of metabotropic glutamate 2 & 3 receptors demonstrate antidepressant-like activity in animal models and hold promise as novel therapeutic agents for the treatment of major depressive disorder. Herein we describe our efforts to pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546651449b4bbed891b5bffae098620b
https://doi.org/10.1016/j.bmcl.2016.10.067
https://doi.org/10.1016/j.bmcl.2016.10.067
Autor:
Jon K. Reel, Akihiko Kato, Gary Gilmour, Keith A. Wafford, Warren J. Porter, Jennifer Li, Brian J. Eastwood, Stephen N. Mitchell, Guy Carter, Scott D. Gleason, Wesley Seidel, Kevin Matthew Gardinier, Jeffrey M. Witkin, Andrew McCarthy
Publikováno v:
Neuropharmacology. 126
6-[(1S)-1-[1-[5-(2-hydroxyethoxy)-2-pyridyl]pyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one (LY3130481 or CERC-611) is a selective antagonist of AMPA receptors containing transmembrane AMPA receptor regulatory protein (TARP) γ-8. This molecule has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f24c685efb6b0fe1f80d42f941e93df
https://pubmed.ncbi.nlm.nih.gov/28757050
https://pubmed.ncbi.nlm.nih.gov/28757050
Autor:
Mark D, Chappell, Renhua, Li, Stephon C, Smith, Bruce A, Dressman, Eric G, Tromiczak, Allie E, Tripp, Maria-Jesus, Blanco, Tatiana, Vetman, Steven J, Quimby, James, Matt, Thomas C, Britton, Adam M, Fivush, Jeffrey M, Schkeryantz, Daniel, Mayhugh, Jon A, Erickson, Mark G, Bures, Carlos, Jaramillo, Mercedes, Carpintero, José Eugenio de, Diego, Mario, Barberis, Susana, Garcia-Cerrada, José F, Soriano, Stephen, Antonysamy, Shane, Atwell, Iain, MacEwan, Bradley, Condon, Christine, Sougias, Jing, Wang, Aiping, Zhang, Kris, Conners, Chris, Groshong, Stephen R, Wasserman, John W, Koss, Jeffrey M, Witkin, Xia, Li, Carl, Overshiner, Keith A, Wafford, Wesley, Seidel, Xu-Shan, Wang, Beverly A, Heinz, Steven, Swanson, John T, Catlow, David W, Bedwell, James A, Monn, Charles H, Mitch, Paul L, Ornstein
Publikováno v:
Journal of medicinal chemistry. 59(24)
As part of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5baf0617bc8dab1818e329dffd2bc0c6
https://pubmed.ncbi.nlm.nih.gov/28002967
https://pubmed.ncbi.nlm.nih.gov/28002967
Autor:
Wesley Seidel Carvalho
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
O Reconhecimento de Entidades Mencionadas (REM) é uma subtarefa da extração de informações e tem como objetivo localizar e classificar elementos do texto em categorias pré-definidas tais como nome de pessoas, organizações, lugares, datas e ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353cbd95446c0612ac23f6f4165585bb
https://doi.org/10.11606/d.45.2012.tde-23052013-104248
https://doi.org/10.11606/d.45.2012.tde-23052013-104248
Publikováno v:
Europe PubMed Central
Aircrew were studied before and after flying one of two routes: San Francisco (SFO) to London (LHR) or SFO to Tokyo (NRT). After an adaptation night, sleep and daytime sleepiness were objectively measured in SFO and during the first layover (L/O) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5cac31d0fe6178f906aea3dc8056eeb2
https://pubmed.ncbi.nlm.nih.gov/3800826
https://pubmed.ncbi.nlm.nih.gov/3800826
Publikováno v:
Europe PubMed Central
Alpha adrenergic agonists such as clonidine are widely used for their antihypertensor effects, but they also cause sedation. The mechanisms underlying soporific effects of such compounds are poorly understood, but appear to involve the alpha-2 adrene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::57e139b4a373d9f1f8581fcfd76d1ea6
http://europepmc.org/abstract/med/7562559
http://europepmc.org/abstract/med/7562559
Publikováno v:
Europe PubMed Central
Novel neuroactive steroids were evaluated for their effects on operant responding, rotorod motor performance, and electroencephalogram recording in rats. Co 134444, Co 177843, and Co 127501 were compared with the prototypical gamma-aminobutyric acid(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff002bd44fe0c32f0a66e92f1d7bc7b8
http://europepmc.org/abstract/med/10565857
http://europepmc.org/abstract/med/10565857