Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wesley Roy Balasubramanian"'
Autor:
Chandrasekhar Abbineni, Kavitha Nellore, Kondapalli Venkata Gowri Chandra Sekhar, Suraj T. Gore, Archana Bhumireddy, Krishna Satya Alapati, V Sumanth Kumar, Susanta Samajdar, B Raghurami Reddy, Subhendu Mukherjee, N V M Rao Bandaru, Wesley Roy Balasubramanian
Publikováno v:
Bioorganicmedicinal chemistry letters. 55
Multiple Splice variants of AR have been reported in the past few years. These splice variants are upregulated in most cases of CRPC resulting in poor prognosis. Most of these variants lack the ligand binding domain (LBD) but still bind to DNA result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929e101465936ae72cb581260f1ad89f
https://pubmed.ncbi.nlm.nih.gov/34767914
https://pubmed.ncbi.nlm.nih.gov/34767914
Autor:
Girish C. Daginakatte, Sasikumar Pottayil, Sudarshan Naremaddepalli, Gundala Chennakrishnareddy, Prasad Bilugudi, Sai Krishna Tangella, Sandeep Patil, Nagesh Gowda, Kiran Aithal, Wesley Roy Balasubramanian, Amit Dhudashiya, Samiulla Dodheri, Kavitha Nellore, Susanta Samajdar, Murali Ramachandra
Publikováno v:
Cancer Research. 82:3500-3500
The CD47/signal regulatory protein alpha axis is a critical regulator of myeloid cell activation and serves as an immune checkpoint for macrophage mediated phagocytosis. Targeting CD47-SIRPα axis is emerging as one of the promising new immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa6e49e95c92aeca0f6e6780025eb67b
https://doi.org/10.1158/1538-7445.am2022-3500
https://doi.org/10.1158/1538-7445.am2022-3500
Autor:
Umarani Subramaniam, Thomas Anthony, Kavitha Nellore, Pratheev Alagapan, Dharvind Balan, Mathura Subangari Dorasamy, Yang Jin Lim, Wai Mun Kong, Mohamad Fairus Abdul Kadir, Sivapriya Marappan, Wesley Roy Balasubramanian
Publikováno v:
Frontiers in Pharmacology. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69b67dad7e711f20926539b2e348587
https://doi.org/10.3389/conf.fphar.2018.63.00017
https://doi.org/10.3389/conf.fphar.2018.63.00017
Autor:
Rajesh Eswarappa, Amit A. Dhudashiya, Kavitha Nellore, DS Samiulla, Sudarshan S. Naremaddepalli, Sasikumar Pottayil, Murali Ramachandra, Archana Bhumireddy, Sandeep Patil, Kiran Aithal, Girish Daginakatte, Gundala Chennakrishna, Wesley Roy Balasubramanian, Priyabrata Chand
Publikováno v:
Cancer Research. 78:3852-3852
Introduction: Most of the immunotherapies currently approved in the clinic target immune checkpoint proteins that suppress T-cell responses. There is growing evidence that the innate immune system also plays an important role in the initiation and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30daaaf99d5f450b2b4ffc6889037e55
https://doi.org/10.1158/1538-7445.am2018-3852
https://doi.org/10.1158/1538-7445.am2018-3852
Autor:
Sandeep Patil, Pottayil G. Sasikumar, DS Samiulla, Amit A. Dhudashiya, Kiran Aithal, Vijaysai Rayavarapu, Chennakrishnareddy Gundala, Wesley Roy Balasubramanian, Archana Bhumireddy, Murali Ramachandra, Sudarshan S. Naremaddepalli, Girish Daginakatte, Anirudha Lakshminarasimhan
Publikováno v:
Molecular Cancer Therapeutics. 17:B007-B007
Antibodies targeting PD-1 and PD-L1 towards stimulation of T cells have revolutionized cancer therapy because of the highly durable response in multiple cancer indications. Although macrophages and other myeloid immune cells offer much promise as eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::202f5a49032a69c53a5a528d7b2ed7f5
https://doi.org/10.1158/1535-7163.targ-17-b007
https://doi.org/10.1158/1535-7163.targ-17-b007
Autor:
Leena Khare Satyam, Sanjeev Giri, Vijay Kamal Ahuja, Narasimha Rao, Manoj Pothuganti, Sreevalsam Gopinath, Sandeep Patil, Vinayak Khairnar, Anirudha Lakshminarasimhan, Dinesh Chikkanna, Kiran Aithal, Chetan Pandit, Gunta Upendra, Wesley Roy Balasubramanian, Jwala Nagaraj, Murali Ramachandra, Sunil Kumar Panigrahi
Publikováno v:
Cancer Research. 77:5108-5108
Diffuse large B cell lymphoma (DLBCL), which accounts for 25% of all lymphomas cases, has been classified into molecular subtypes including germinal center B cell like (GCB) DLBCL, activated B cell-like (ABC) DLBCL, and primary mediastinal B cell lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8799907eccab7f6e13d77ddf29b6b501
https://doi.org/10.1158/1538-7445.am2017-5108
https://doi.org/10.1158/1538-7445.am2017-5108
Autor:
Thomas Antony, Shekar Chelur, Chetan Pandit, Kavitha Nellore, Sreevalsam Gopinath, Girish Daginakatte, Bharathi Raja Ainan, Aravind Basavaraju, Subhendu Mukherjee, Venkateshwar Rao Gummadi, Murali Ramachandra, Susanta Samajdar, Sanjeev Giri, Sivapriya Marappan, Wesley Roy Balasubramanian
Publikováno v:
Cancer Research. 76:4798-4798
Interleukin-1 receptor associated kinases (IRAKs) are serine/threonine protein kinases belonging to the tyrosine-like kinase (TLK) family. IRAKs function as mediators of Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf485254e7603791b9fd90480378f12
https://doi.org/10.1158/1538-7445.am2016-4798
https://doi.org/10.1158/1538-7445.am2016-4798
Autor:
Ravi Krishna Babu Damarla, Ravi K Ujjinamatada, Kavitha Nellore, Samiulla S Dodheri, Shekar Chelur, K.B Charamanna, Subhendu Mukherjee, CH Sandeep Reddy, Wesley Roy Balasubramanian, Sanjay B Rathod, Anirudha Lakshminarasimhan, K Narasimha Rao, Anuradha Ramanathan, Natarajan Mahalingam, AR Girish, Susanta Samajdar, Chetan Pandit, Murali Ramachandra
Publikováno v:
The Journal of Immunology. 196:139.10-139.10
The nuclear hormone receptor RORγ controls the differentiation of Th17 cells that plays a key pro-inflammatory role in a variety of autoimmune diseases. RORγ inverse agonists from multiple structural classes were discovered and screened in a RORγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9308fb10204b47104af8ba261956839
https://doi.org/10.4049/jimmunol.196.supp.139.10
https://doi.org/10.4049/jimmunol.196.supp.139.10
Autor:
Chetan Pandit, Sivapriya Marappan, Shekar Chelur, Sreevalsam Gopinath, Venkateshwar Rao, Wesley Roy Balasubramanian, Kavitha Nellore, Sanjeev Giri, Bharathi Raja Ainan, Susanta Samajdar, Murali Ramachandra, Thomas Antony, Girish Daginakatte, Aravind Basavaraju
Publikováno v:
Molecular Cancer Therapeutics. 14:C191-C191
Interleukin-1 receptor associated kinases (IRAKs) are serine/threonine protein kinases belonging to tyrosine-like kinase (TLK) family. The IRAK family consists of IRAK1, IRAK2, IRAK3 and IRAK4 out of which only IRAK1 and IRAK4 exhibit kinase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a52ccda1bb9e5ec6a81277f16eb2604
https://doi.org/10.1158/1535-7163.targ-15-c191
https://doi.org/10.1158/1535-7163.targ-15-c191
Autor:
Chia-Hung Wu, Wesley Roy Balasubramanian, Shih-En Chang, George Hsu, Ya-Ping Ko, Steve R. Roffler, Zeljko M. Prijovich, Kai-Chuan Chen
Publikováno v:
Biotechnology and Applied Biochemistry. 40:167
Expression of recombinant proteins in mammalian cells is useful for obtaining products with normal post-translational modifications. We describe a simple and economical method for the production of milligram levels of proteins in murine fibroblasts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483a965cda1b2c94ca9498237f56fead
https://doi.org/10.1042/ba20030184
https://doi.org/10.1042/ba20030184