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pro vyhledávání: '"Wesley R, Naeimi"'
Autor:
Wesley R. Naeimi, Tricia R. Serio
Publikováno v:
Viruses, Vol 14, Iss 8, p 1635 (2022)
The formation of amyloid fibers is associated with a diverse range of disease and phenotypic states. These amyloid fibers often assemble into multi-protofibril, high-order architectures in vivo and in vitro. Prion propagation in yeast, an amyloid-bas
Externí odkaz:
https://doaj.org/article/7e594b75e7dc4457bb22b6d56826fee5
Publikováno v:
Molecular Microbiology. 104:125-143
The ability of a yeast cell to propagate [PSI+ ], the prion form of the Sup35 protein, is dependent on the molecular chaperone Hsp104. Inhibition of Hsp104 function in yeast cells leads to a failure to generate new propagons, the molecular entities n
Publikováno v:
Molecular microbiology. 104(1)
The ability of a yeast cell to propagate [PSI
Autor:
Mick F. Tuite, Wesley R. Naeimi
Publikováno v:
The Biochemist. 32:30-33
In the mid-1960s, two unusual genetic determinants were discovered in the yeast Saccharomyces cerevisiae. In genetic crosses, these determinants, called [PSI+] and [URE3] respectively, were found not to be inherited according to Mendel's laws. Little
Autor:
Mick F. Tuite, Wesley R. Naeimi
Publikováno v:
Reviews in Cell Biology and Molecular Medicine
Prions were originally identified as novel protein-only, disease-causing agents associated with brain degenerative diseases termed transmissible spongiform encephalopathies (TSEs). Prions were subsequently discovered in fungi, where they influence a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4db0dfb5db9c05abbbae2d487bf33219
https://doi.org/10.1002/3527600906.mcb.201100029
https://doi.org/10.1002/3527600906.mcb.201100029
Autor:
Geraldine Sanders, Wesley R. Naeimi, Rachael Hutton, Michael Breitenbach, Jane E. Leadsham, Campbell W. Gourlay, Samantha Giannaki, Emma L. Bastow
Publikováno v:
Cell Metabolism. (2):279-286
SummaryMany disease states, including the aging process, are associated with the accumulation of mitochondria harboring respiratory dysfunction. Mitochondrial dysfunction is often accompanied by increased ROS levels that can contribute to cellular dy