Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Wesley M. Sharman"'
1
A new procedure for the synthesis of water-soluble tri-cationic and -anionic phthalocyanines
Autor: Wesley M. Sharman, Johan E. van Lier
Publikováno v: Journal of Porphyrins and Phthalocyanines. :651-658
A series of water-soluble tri-anionic and -cationic substituted phthalocyanines has been synthesized via iodinated boron subphthalocyanines. The latter were opened with differently substituted diiminoisoindolines via the Kobayashi ring expansion reac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d6a19268f59f7ded987133d0b0713e4
https://doi.org/10.1142/s1088424605000769
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2
Targeted photodynamic therapy via receptor mediated delivery systems
Autor: Johan E. van Lier, Cynthia M Allen, Wesley M. Sharman
Publikováno v: Advanced Drug Delivery Reviews. 56:53-76
Targeted photodynamic therapy (PDT) offers the opportunity of enhancing photodynamic efficiency by directly targeting diseased cells and tissues. While antibody-conjugates have received the most attention, cellular transformations offer numerous othe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45215f2aa9cf1e3879c956d839cc5c2
https://doi.org/10.1016/j.addr.2003.08.015
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3
Attenuation of photodynamically induced apoptosis by an RGD containing peptide
Autor: Wesley M. Sharman, Carole La Madeleine, Joseph M. Weber, Cynthia M. Allen, Johan E. van Lier
Publikováno v: Photochemical & Photobiological Sciences. 1:246-254
Research efforts have focused on the improvement of already established photodynamic therapy (PDT) protocols. The use of adjunct therapies is one such route. The integrin class of receptors mediates extracellular matrix signals through a complex maze
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ad68c8a7b9e6fc49b2cfcc6dc8086a
https://doi.org/10.1039/b109979e
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5
Current status of phthalocyanines in the photodynamic therapy of cancer
Autor: Johan E. van Lier, Wesley M. Sharman, Cynthia M. Allen
Publikováno v: Journal of Porphyrins and Phthalocyanines. :161-169
Photodynamic therapy is a binary treatment now accepted in clinic for various malignancies in several countries around the world. Phthalocyanine molecules are second-generation photosensitizers with enhanced photophysical and photochemical properties
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e32bc91f1bb98e5f025859890a5e94ce
https://doi.org/10.1002/jpp.324
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6
Use of palladium catalysis in the synthesis of novel porphyrins and phthalocyanines
Autor: J. E. Van Lier, Wesley M. Sharman
Publikováno v: Journal of Porphyrins and Phthalocyanines. :441-453
Palladium catalysts offer a rich and highly versatile chemistry for the synthesis of novel porphyrins and phthalocyanines. These mild and flexible reactions have been used extensively in the preparation of interesting porphyrins and phthalocyanines,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b9691fb4b5a5343644b22e558b697b6
https://doi.org/10.1002/1099-1409(200008)4:5<441::aid-jpp275>3.0.co
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7
Photodynamic Therapy: Tumor Targeting with Adenoviral Proteins
Autor: Johan E. van Lier, René Ouellet, Cynthia M. Allen, Réjean Langlois, Wesley M. Sharman, Joseph M. Weber, Carole La Madeleine
Publikováno v: Photochemistry and Photobiology. 70:512-523
A brief summary of the mechanisms involved in photodynamic therapy (PDT) and the role of delivery vehicles for photosensitizer targeting is addressed. Phthalocyanines (Pc) have been coupled to adenovirus type 2 capsid proteins including the hexon, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bfa4fdcb9ff143a4f2d25d7f8b824be
https://doi.org/10.1111/j.1751-1097.1999.tb08246.x
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8
Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings
Autor: Johan E. van Lier, Svetlana V. Kudrevich, Wesley M. Sharman
Publikováno v: Tetrahedron Letters. 37:5831-5834
The synthesis and characterization of a series of phthalocyanine derivatives bearing phosphonate substituents directly bound to the aromatic rings of the phthalocyanine is described. These novel water-soluble phthalocyanine tetraphosphonates are of i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73205b1066ade438461c48c67f908b6d
https://doi.org/10.1016/0040-4039(96)01243-9
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10
Synthesis and photodynamic activity of novel asymmetrically substituted fluorinated phthalocyanines
Autor: Wesley M. Sharman and, Johan E. van Lier
Publikováno v: Bioconjugate chemistry. 16(5)
A series of asymmetrically substituted dodecafluorinated phthalocyanines has been synthesized via the Kobayashi ring expansion reaction of the corresponding dodecafluorinated boron subphthalocyanine with differently substituted 1,3-diiminoisoindoline
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b07018d5f94989d73f79985d2e2ba8
https://pubmed.ncbi.nlm.nih.gov/16173794
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