Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Wesley Gladwell"'
Autor:
Wesley Gladwell, Oriana Yost, Heather Li, Whitney J. Bell, Shih-Heng Chen, James M. Ward, Steven R. Kleeberger, Michael A. Resnick, Daniel Menendez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16793 (2023)
Identifying and understanding genetic factors that influence the propagation of the human respiratory syncytial virus (RSV) can lead to health benefits and possibly augment recent vaccine approaches. We previously identified a p53/immune axis in whic
Externí odkaz:
https://doaj.org/article/8a3af7584ab946568481c13ae7756797
Autor:
Nick L. Dobson, Steven R. Kleeberger, Adam B. Burkholder, Dianne M. Walters, Wesley Gladwell, Kevin Gerrish, Heather L. Vellers
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14507 (2023)
Interstitial lung diseases (ILDs) are lethal lung diseases characterized by pulmonary inflammation and progressive lung interstitial scarring. We previously developed a mouse model of ILD using vanadium pentoxide (V2O5) and identified several gene ca
Externí odkaz:
https://doaj.org/article/5978b6b6717e4e70ae1de1288a5f6447
Autor:
Heather L. Vellers, Hye-Youn Cho, Wesley Gladwell, Kevin Gerrish, Janine H. Santos, Gaston Ofman, Laura Miller-DeGraff, T. Beth Mahler, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 760 (2022)
Approximately 1 in 10 newborns are born preterm and require supplemental oxygen (O2) in an extrauterine environment following birth. Supplemental O2 can induce oxidative stress that can impair mitochondrial function, resulting in lung injury and incr
Externí odkaz:
https://doaj.org/article/37b95ba35a3d4e7dad2fc02c2e9396ef
Autor:
Hye-Youn Cho, Laura Miller-DeGraff, Ligon A. Perrow, Wesley Gladwell, Vijayalakshmi Panduri, Fred B. Lih, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1874 (2021)
NRF2 protects against oxidant-associated airway disorders via cytoprotective gene induction. To examine if NRF2 is an important determinant of respiratory syncytial virus (RSV) susceptibility after neonate lung injury, Nrf2-deficient (Nrf2−/−) an
Externí odkaz:
https://doaj.org/article/17dae43bb82341c1b48a3975fc454159
Autor:
Vijayalakshmi Panduri, Wesley Gladwell, Laura Miller-DeGraff, Ligon Perrow, Hye-Youn Cho, Steven R. Kleeberger, Fred B. Lih
Publikováno v:
Antioxidants, Vol 10, Iss 1874, p 1874 (2021)
Antioxidants; Volume 10; Issue 12; Pages: 1874
Antioxidants
Antioxidants; Volume 10; Issue 12; Pages: 1874
Antioxidants
NRF2 protects against oxidant-associated airway disorders via cytoprotective gene induction. To examine if NRF2 is an important determinant of respiratory syncytial virus (RSV) susceptibility after neonate lung injury, Nrf2-deficient (Nrf2−/−) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fc5e19f12b7614719f0312e4e87c4d
https://doi.org/10.3390/antiox10121874
https://doi.org/10.3390/antiox10121874
Autor:
Daniel Menendez, Oriana Yost, Michael A. Resnick, Heather Li, Wesley Gladwell, Steve R. Kleeberger
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71121f11399dcb218937694e848e8aef
https://doi.org/10.1096/fasebj.2018.32.1_supplement.755.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.755.3
Autor:
Zachary R. McCaw, Shweta Trivedi, Wesley Gladwell, Pierre R. Bushel, Kirsten C. Verhein, Steven R. Kleeberger
Publikováno v:
Environmental Health Perspectives
Background Ozone is a highly toxic air pollutant and global health concern. Mechanisms of genetic susceptibility to ozone-induced lung inflammation are not completely understood. We hypothesized that Notch3 and Notch4 are important determinants of su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323aae9e05b3da4ef8c010f51da1ed01
http://europepmc.org/articles/PMC4529014
http://europepmc.org/articles/PMC4529014
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2013 (2013)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Ozone (O3) is a strong oxidant in air pollution that has harmful effects on airways and exacerbates respiratory disorders. The transcription factor Nrf2 protects airways from oxidative stress through antioxidant response element-bearing defense gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaf43c36c4003ef16d1f74d49985c20
https://doi.org/10.1155/2013/254069
https://doi.org/10.1155/2013/254069
Autor:
Xuting Wang, Steven R. Kleeberger, Douglas A. Bell, Wesley Gladwell, Laura Miller-DeGraff, Ligon Perrow, Bennett Van Houten, Masayuki Yamamoto, Lester Kobzik, Jennifer Fostel, Vijayalakshmi Panduri, Hye Youn Cho
Publikováno v:
Antioxidants & Redox Signaling. 17:1066-1082
Aims: Nrf2 is an essential transcription factor for protection against oxidant disorders. However, its role in organ development and neonatal disease has received little attention. Therapeutically administered oxygen has been considered to contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ad26af47fbfbeb8df0e8f9fefdb821
https://doi.org/10.1089/ars.2011.4288
https://doi.org/10.1089/ars.2011.4288
Autor:
Wesley Gladwell, Christina T. Teng
Publikováno v:
Biochemistry and Cell Biology. 84:381-384
The lactoferrin protein possesses antimicrobial and antiviral activities. It is also involved in the modulation of the immune response. In a normal healthy individual, lactoferrin plays a role in the front-line host defense against infection and in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d7be014527873f3b3c7db68686680a
https://doi.org/10.1139/o06-035
https://doi.org/10.1139/o06-035