Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Wesley G. Beamer"'
Autor:
Jon E. Wergedal, Cheryl L. Ackert-Bicknell, Wesley G. Beamer, Subburaman Mohan, David J. Baylink, Apurva K. Srivastava
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1724-1734 (2007)
The NZB/B1NJ (NZB) mouse strain exhibits high cholesterol and HDL levels in blood compared with several other strains of mice. To study the genetic regulation of blood lipid levels, we performed a genome-wide linkage analysis in 542 chow-fed F2 femal
Externí odkaz:
https://doaj.org/article/500e8167d12f440f92d28e0bd2873d03
Publikováno v:
Genetics and Molecular Biology, Vol 30, Iss 2, Pp 322-329 (2007)
Humans and guinea pigs are species which are unable to synthesize ascorbic acid (vitamin C) because, unlike rodents, they lack the enzyme L-gulonolactone oxidase (Gulo). Although the phenotype of lacking vitamin C in humans, named scurvy, has long be
Externí odkaz:
https://doaj.org/article/fa1355191fc84efc9c3f49edbd49659a
The adrenocortical dysplasia (acd) mouse mutation arose spontaneously in the dwarf strain in 1985 at the Jackson Laboratory. Both the background strain and the acd/acd mice are agouti/leaden. Mice homozygous for the adrenocortical dysplasia mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9155715f2bbd074f4f1b0aeff11b94d
https://doi.org/10.1201/9781003068952-18
https://doi.org/10.1201/9781003068952-18
Autor:
Kathryn L. Shultz, Edward S. Yaskowiak, Kaitlyn R. Stanford, Kerri N. Smith, Wesley G. Beamer, Ann M. Dorward
Publikováno v:
Epigenetics
Females of the SWR/Bm (SWR) inbred mouse strain possess a unique susceptibility to juvenile-onset tumors originating from the granulosa cells (GC) of the ovarian follicles. Tumor susceptibility is an inherited, polygenic trait in SWR females, minimal
Autor:
Benjamin J. Adler, Kenneth R. Shroyer, Danielle E. Green, Janet Rubin, Wesley G. Beamer, Clinton T. Rubin, M. Ete Chan, Danielle M. Frechette, Gabriel M. Pagnotti
Publikováno v:
Bone. 51:570-577
Cancer progression is often paralleled by a decline in bone mass, raising risk of fracture. Concerns persist regarding anabolic interventions for skeletal protection, as these may inadvertently exacerbate neoplastic tissue expansion. Given bone's inh
Autor:
Douglas P. Kiel, David Karasik, Shirng-Wern Tsaih, Cheryl L. Ackert-Bicknell, Serkalem Demissie, Beverly Paigen, Wesley G. Beamer, L. Adrienne Cupples, Yi-Hsiang Hsu
Publikováno v:
Bone
Bone; Vol 50
Bone; Vol 50
Trps1 has been proposed as a candidate gene for a mouse bone mineral density (BMD) QTL on Chromosome (Chr) 15, but it remained unclear if this gene was associated with BMD in humans. We used newly available data and advanced bioinformatics techniques
Autor:
Lindsay G. Horton, Leah Rae Donahue, Wesley G. Beamer, Kathryn L. Shultz, Clifford J. Rosen, Harold F Coombs
Publikováno v:
Journal of Bone and Mineral Research. 27:47-57
The mid-distal region of mouse chromosome 4 (Chr 4) is homologous with human Chr 1p36. Previously, we reported that mouse Chr 4 carries a quantitative trait locus (QTL) with strong regulatory effect on volumetric bone mineral density (vBMD). The inte
Autor:
Wesley G. Beamer, Clifford J. Rosen, Ernesto Canalis, Xinchun Shen, Victoria E. DeMambro, David R. Clemmons, Mary L. Bouxsein, Masanobu Kawai, Anne Breggia
Publikováno v:
Journal of Biological Chemistry. 286:14670-14680
Insulin-like growth factor-binding protein 2 (IGFBP-2) is a member of a family of six highly conserved IGFBPs that are carriers for the insulin-like growth factors (IGFs). IGFBP-2 levels rise during rapid neonatal growth and at the time of peak bone