Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wesley F. Seidel"'
Autor:
Kjell Svensson, Kimberley Jackson, Susan K Luecke, Gerard J. Marek, John Hart, Daniel Ray Mayhugh, Dale M. Edgar, Robert A. Dean, Albert Khilevich, Kenneth W. Perry, Stephen F. Chaney, Christian C. Felder, Jeffrey M. Witkin, Mark J. Benvenga, Anne T. Quets, Sitra Tauscher-Wisniewski, Xushan Wang, James E Eckstein, Deanna L Marlow, Jason Katner, Ming-Shang Kuo, Phillip J Ebert, Linda M. Rorick-Kehn, Beverly A. Heinz, Steven P. Swanson, Julie F. Falcone, Bradley L. Ackermann, Xia Li, Deyi Zhang, John T. Catlow, Alexander Nikolayev, Linda K. Thompson, Carl D Overshiner, Keith A. Wafford, Wesley F. Seidel, Kurt Rasmussen, Jeffrey M. Schkeryantz, Matthew J. Fell
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 336(1)
The normalization of excessive glutamatergic neurotransmission through the activation of metabotropic glutamate 2 (mGlu2) receptors may have therapeutic potential in a variety of psychiatric disorders, including anxiety/depression and schizophrenia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91597fbae3f35360c2e3013a51d98d9
https://pubmed.ncbi.nlm.nih.gov/20947638
https://pubmed.ncbi.nlm.nih.gov/20947638
Publikováno v:
Drug Investigation. 3:148-156
In a double-blind, randomised, comparative study, 44 healthy volunteers received alprazolam 0.5mg, buspirone 5mg or diazepam 5mg orally 3 times each day for 7 consecutive days. Daytime sedation was evaluated on the first and seventh treatment days by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8728fdee6b66e4bba21f3f53fd3ecfd8
https://doi.org/10.1007/bf03259556
https://doi.org/10.1007/bf03259556
Publikováno v:
Neuroscience Letters. 125:125-128
Rats with suprachiasmatic nuclei (SCN) lesions did not show increased sleep after triazolam (TRZ) injections at any dose from 0.2 to 1.6 mg/kg, whereas 0.4 mg/kg TRZ given intact rats in the middle of their activity phase significantly increased slee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecb2a4980bbe83c7cdd3dfdfe25ba81
https://doi.org/10.1016/0304-3940(91)90007-g
https://doi.org/10.1016/0304-3940(91)90007-g
Publikováno v:
Journal of Allergy and Clinical Immunology. 86:1029-1033
Alertness is a vital function, and medications that do not impair this vital function are clinically desirable in terms of safety. In a comparative study to measure daytime alertness objectively, 60 men and women in good health were assigned to recei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7189dd1bb42ba7203c12f23bd5ed2180
https://doi.org/10.1016/s0091-6749(05)80249-0
https://doi.org/10.1016/s0091-6749(05)80249-0
Publikováno v:
Neurobiology of aging. 12(5)
This study investigated whether a sensitive, physiological measure of alertness/sleepiness, the Multiple Sleep Latency Test (MSLT), was related to neuropsychological test performance in elderly individuals. We hypothesized that the greater likelihood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786538a5d0f7c19c0ecb49dfb79d4c57
https://pubmed.ncbi.nlm.nih.gov/1770981
https://pubmed.ncbi.nlm.nih.gov/1770981
Publikováno v:
Psychopharmacology. 105(3)
Rats entrained to 12-h on /12-h off light schedule and injected with triazolam 0.4 mg/kg at the mid-point of their activity phase (6 h after lights out: circadian time = CT-18) had a stronger hypnotic response than animals free-running in constant da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4446a125fceaba0306966eca50866dc
https://pubmed.ncbi.nlm.nih.gov/1798833
https://pubmed.ncbi.nlm.nih.gov/1798833
Publikováno v:
Psychopharmacology. 87:194-197
Eighteen non-anxious volunteers underwent sleep recordings and daytime tests of sleepiness, performance, and mood while receiving, either alprazolam 0.5 mg b.i.d. or diazepam 5 mg b.i.d. for 7 consecutive days. Recordings and tests were done before t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc32d2b692392d08b6e5765a130368c8
https://doi.org/10.1007/bf00431806
https://doi.org/10.1007/bf00431806
Autor:
W C Dement, Ismet Karacan, Merrill M. Mitler, Frank Zorick, Donald L. Bliwise, Thomas Roth, Wesley F. Seidel
Publikováno v:
Sleep. 6:156-163
Sleep laboratory hypnotic medication trials typically determine efficacy by examining changes in polysomnographically recorded sleep. We introduce the use of daytime sleepiness, as assessed by the Multiple Sleep Latency Test (MSLT), as a criterion fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658398ddcdee6148830b6de9caebc455
https://doi.org/10.1093/sleep/6.2.156
https://doi.org/10.1093/sleep/6.2.156
Publikováno v:
Sleep. 5:S28-S45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d7f4cceabdd80d08a25b7043bd8af1
https://doi.org/10.1093/sleep/5.suppl_1.s28
https://doi.org/10.1093/sleep/5.suppl_1.s28
Autor:
Wesley F. Seidel, William C. Dement
Publikováno v:
Sleep. 5:S182-S190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402df3eddd0f66f06f9d00fe675feb0a
https://doi.org/10.1093/sleep/5.s2.s182
https://doi.org/10.1093/sleep/5.s2.s182