Výsledky vyhledávání - "Wesley Edward Smith"

The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids

Autor: Erin S. Bolstad, Holly D. Cox, John M. Gerdes, Richard J. Bridges, Christina N. Carrigan, Sarjubhai A. Patel, Wesley Edward Smith, Charles M. Thompson

Publikováno v: Bioorganicmedicinal chemistry letters. 24(3)

Substituted quinoline-2,4-dicarboxylates (QDCs) are conformationally-restricted mimics of glutamate that were previously reported to selectively block the glutamate vesicular transporters (VGLUTs). We find that expanding the QDC scaffold to benzoquin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52948db16bc67adef4e4da69626e8168
https://pubmed.ncbi.nlm.nih.gov/24424130

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