Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wesley C. LaBarge"'
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103824- (2022)
Summary: Human cardiac-muscle patches (hCMPs) constructed from induced pluripotent stem cells derived cardiomyocytes (iCMs) can replicate the genetics of individual patients, and consequently be used for drug testing, disease modeling, and therapeuti
Externí odkaz:
https://doaj.org/article/9a287071f4764a90b5a4c6c09e927e28
Publikováno v:
SSRN Electronic Journal.
Human cardiac-muscle patches (hCMPs) constructed from cardiomyocytes (CMs) that have been differentiated from human induced-pluripotent stem cells (hiPSCs) can fully replicate the genetic background of each individual patient and, consequently, can b
Autor:
Andrew E. Pollard, Ramaswamy Kannappan, Asher Kahn-Krell, Vladimir G. Fast, Alan W. Eberhardt, Wesley C. LaBarge, Xi Lou, Danielle Pretorius, Jianyi Zhang, Joel L. Berry
Publikováno v:
Biomed Mater
Cardiac tissue surrogates show promise for restoring mechanical and electrical function in infarcted left ventricular (LV) myocardium. For these cardiac surrogates to be useful in vivo, they are required to support synchronous and forceful contractio
Autor:
Wesley C. LaBarge, Danielle Pretorius, Andres Morales, Ramaswamy Kannappan, Asher Kahn-Krell, Jianyi Zhang
Publikováno v:
Micromachines, Vol 10, Iss 9, p 570 (2019)
Micromachines
Volume 10
Issue 9
Micromachines
Volume 10
Issue 9
Free from the limitations posed by exogenous scaffolds or extracellular matrix-based materials, scaffold-free engineered tissues have immense clinical potential. Biomaterials may produce adverse responses, interfere with cell–cell interaction, or a
Autor:
Jianyi Zhang, Wesley C. LaBarge, Ramaswamy Kannappan, Vladimir G. Fast, Danielle Pretorius, Saidulu Mattappally, Joel L. Berry
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219442 (2019)
PLoS ONE, Vol 14, Iss 7, p e0219442 (2019)
Functional myocardium derived from human induced pluripotent stem cells (hiPSCs) can be impactful for cardiac disease modeling, drug testing, and the repair of injured myocardium. However, when hiPSCs are differentiated into cardiomyocytes, they do n