Zobrazeno 1 - 10
of 6 486
pro vyhledávání: '"Wesley C"'
Autor:
Michael K. Fenwick, Phillip G. Pierce, Jan Abendroth, Kayleigh F. Barrett, Lynn K. Barrett, Kalinga Bowatte, Ryan Choi, Ian Chun, Deborah G. Conrady, Justin K. Craig, David M. Dranow, Bradley Hammerson, Tate Higgins, Donald D. Lorimer, Peer Lukat, Stephen J. Mayclin, Stephen Nakazawa Hewitt, Ying Po Peng, Ashwini Shanbhogue, Hayden Smutney, Matthew Z. Z. Stigliano, Logan M. Tillery, Hannah S. Udell, Ellen G. Wallace, Amy E. DeRocher, Isabelle Q. Phan, Bart L. Staker, Sandhya Subramanian, Wesley C. Van Voorhis, Wulf Blankenfeldt, Rolf Müller, Thomas E. Edwards, Peter J. Myler
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Griselimycin, a cyclic depsidecapeptide produced by Streptomyces griseus, is a promising lead inhibitor of the sliding clamp component of bacterial DNA polymerases (β-subunit of Escherichia coli DNA pol III). It was previously shown to inhi
Externí odkaz:
https://doaj.org/article/1a656d43c6764dba945de1b0c7cfbe21
Autor:
Kang Du, Juliana Morena Bonita Ricci, Yuan Lu, Mateo Garcia-Olazabal, Ronald B. Walter, Wesley C. Warren, Tristram O. Dodge, Molly Schumer, Hyun Park, Axel Meyer, Manfred Schartl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Hybridization has been recognized to play important roles in evolution, however studies of the genetic consequence are still lagging behind in vertebrates due to the lack of appropriate experimental systems. Fish of the genus Xiphophorus are
Externí odkaz:
https://doaj.org/article/4d8441e5a6574809984fdfd09eaf89f1
Autor:
Jacky C. K. Ng, Iris W. Y. Lai, Algae K. Y. Au, Joanne Y. H. Chong, Wesley C. H. Wu, Victor C. Y. Lau
Publikováno v:
International Journal of Adolescence and Youth, Vol 29, Iss 1 (2024)
A great deal of investigation has been devoted to studying whether academic achievement is linked to adolescents’ life satisfaction, whereas limited studies have focused on conduct achievement, which serves as another common kind of achievement in
Externí odkaz:
https://doaj.org/article/017ee3d0faf149cca90b6ee75593b726
Autor:
Muskan Kapoor, Enrique Sapena Ventura, Amy Walsh, Alexey Sokolov, Nancy George, Sunita Kumari, Nicholas J. Provart, Benjamin Cole, Marc Libault, Timothy Tickle, Wesley C. Warren, James E. Koltes, Irene Papatheodorou, Doreen Ware, Peter W. Harrison, Christine Elsik, Galabina Yordanova, Tony Burdett, Christopher K. Tuggle
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe agriculture genomics community has numerous data submission standards available, but the standards for describing and storing single-cell (SC, e.g., scRNA- seq) data are comparatively underdeveloped.MethodsTo bridge this gap, we lever
Externí odkaz:
https://doaj.org/article/133bd036ce5c49aa9b32e0629a9046ce
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Henry’s law constant, which describes the proportionality of dissolved gas to partial pressure of free gas in liquid–gas equilibrium systems, can also be applied to mass transport applications. In this work, we investigated an approach f
Externí odkaz:
https://doaj.org/article/54ce9004e05447d1be04d3f2df6495d2
Autor:
Thao T. Truong, Karissa Crawford, Ichih Wang-McGuire, Kendal Jensen, Aisha Mushtaq, Nicole A. P. Lieberman, Frederick S. Buckner, Wesley C. Van Voorhis, Brad T. Cookson, Stephen J. Salipante, Joshua A. Lieberman
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Leishmaniasis is a rare disease in the United States, with an estimated annual incidence of dozens of cases occurring primarily in travelers, migrants, and military personnel. True disease incidence is unknown, since leishmaniasis is not a n
Externí odkaz:
https://doaj.org/article/ea705f21d419493a84fac5e5d369c85f
Autor:
Maria Cristina Ferreira de Sousa, Dennis Imhof, Kai Pascal Alexander Hänggeli, Ryan Choi, Matthew A. Hulverson, Samuel L.M. Arnold, Wesley C. Van Voorhis, Erkang Fan, Sánchez-Sánchez Roberto, Luis M. Ortega-Mora, Andrew Hemphill
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100553- (2024)
Toxoplasma gondii and Neospora caninum are major worldwide morbidity-causing pathogens. Bumped kinase inhibitors (BKIs) are a compound class that has been optimized to target the apicomplexan calcium-dependent protein kinase 1 (CDPK1) – and several
Externí odkaz:
https://doaj.org/article/5d45770ad7984b1f80ca4e9a68cdce54
Autor:
Rachel A. Carroll, Edward S. Rice, William J. Murphy, Leslie A. Lyons, Francoise Thibaud-Nissen, Lyndon M. Coghill, William F. Swanson, Karen A. Terio, Tyler Boyd, Wesley C. Warren
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The fishing cat, Prionailurus viverrinus, faces a population decline, increasing the importance of maintaining healthy zoo populations. Unfortunately, zoo-managed individuals currently face a high prevalence of transitional cell carcinoma (T
Externí odkaz:
https://doaj.org/article/72ae249a5a97496cb3fe943ec456335f
Autor:
Cindy X. Zhang, Thomas M. Conrad, David Hermann, Melita A. Gordon, Eric Houpt, Pui‐Ying Iroh Tam, Khuzwayo C. Jere, Wilfred Nedi, Darwin J. Operario, Jacob Phulusa, Gerald V. Quinnan Jr, Leigh A. Sawyer, Lynn K. Barrett, Herbert Thole, Neema Toto, Wesley C. Van Voorhis, Samuel L. M. Arnold
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 410-423 (2024)
Abstract Oral drug absorption kinetics are usually established in populations with a properly functioning gastrointestinal tract. However, many diseases and therapeutics can alter gastrointestinal physiology and cause diarrhea. The extent of diarrhea
Externí odkaz:
https://doaj.org/article/eb41958c05d84d0fb5af26988b5b95cf
Autor:
Wesley C. Burkett, Ziyi Zhao, Meredith A. Newton, Wenchuan Sun, Boer Deng, Angeles Alvarez Secord, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 603-614 (2023)
AbstractPurpose Uterine serous carcinoma (USC) exhibits worse survival rates compared to the endometrioid subtype, and there is currently no effective treatment options for recurrence of this disease after platinum-based chemotherapy. Activation of P
Externí odkaz:
https://doaj.org/article/ecb88b1b26b24a17813aa38f363d5220