Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Wesley De Neve"'
Assessing the reliability of point mutation as data augmentation for deep learning with genomic data
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Deep neural networks (DNNs) have the potential to revolutionize our understanding and treatment of genetic diseases. An inherent limitation of deep neural networks, however, is their high demand for data during training. To overco
Externí odkaz:
https://doaj.org/article/979cd6ed040146ed80923cd0aca97af4
Autor:
Esla Timothy Anzaku, Mohammed Aliy Mohammed, Utku Ozbulak, Jongbum Won, Hyesoo Hong, Janarthanan Krishnamoorthy, Sofie Van Hoecke, Stefan Magez, Arnout Van Messem, Wesley De Neve
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract Trypanosomiasis, a neglected tropical disease (NTD), challenges communities in sub-Saharan Africa and Latin America. The World Health Organization underscores the need for practical, field-adaptable diagnostics and rapid screening tools to a
Externí odkaz:
https://doaj.org/article/b624826857cb45d29b9f63dc1d90e105
Autor:
Ho-min Park, Jongbum Won, Yunseol Park, Esla Timothy Anzaku, Joris Vankerschaver, Arnout Van Messem, Wesley De Neve, Hyunjin Shim
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-6 (2023)
Abstract Background CRISPR-Cas-Docker is a web server for in silico docking experiments with CRISPR RNAs (crRNAs) and Cas proteins. This web server aims at providing experimentalists with the optimal crRNA-Cas pair predicted computationally when prok
Externí odkaz:
https://doaj.org/article/722e0901285745c1a1937105abefba2a
Autor:
Ho-min Park, Yunseol Park, Urta Berani, Eunkyu Bang, Joris Vankerschaver, Arnout Van Messem, Wesley De Neve, Hyunjin Shim
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract RNA–protein interactions are crucial for diverse biological processes. In prokaryotes, RNA–protein interactions enable adaptive immunity through CRISPR-Cas systems. These defence systems utilize CRISPR RNA (crRNA) templates acquired from
Externí odkaz:
https://doaj.org/article/b308d82b646046378486402cc62f7eb7
Autor:
Morgane Boone, Pathmanaban Ramasamy, Jasper Zuallaert, Robbin Bouwmeester, Berre Van Moer, Davy Maddelein, Demet Turan, Niels Hulstaert, Hannah Eeckhaut, Elien Vandermarliere, Lennart Martens, Sven Degroeve, Wesley De Neve, Wim Vranken, Nico Callewaert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The exact protein features that control passage through the eukaryotic secretory system remain largely unknown. Here the authors report SECRiFY which they use to evaluate the secretory potential of polypeptides on a proteome-wide scale in yeast, reve
Externí odkaz:
https://doaj.org/article/043a1799d9594a9ab4b4cd01c3c5aabe
Autor:
Ho-min Park, Sanghyeon Park, Maria Krishna de Guzman, Ji Yeon Baek, Tanja Cirkovic Velickovic, Arnout Van Messem, Wesley De Neve
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Environmental monitoring of microplastics (MP) contamination has become an area of great research interest, given potential hazards associated with human ingestion of MP. In this context, determination of MP concentration is essential. However, cheap
Externí odkaz:
https://doaj.org/article/080e17ff1c914e8a91e60496e9f84e44
Autor:
Morgane Boone, Pathmanaban Ramasamy, Jasper Zuallaert, Robbin Bouwmeester, Berre Van Moer, Davy Maddelein, Demet Turan, Niels Hulstaert, Hannah Eeckhaut, Elien Vandermarliere, Lennart Martens, Sven Degroeve, Wesley De Neve, Wim Vranken, Nico Callewaert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/59e221e1945e465da5a2c8878e6d8f64
Autor:
Ho-Min Park, Yunseol Park, Joris Vankerschaver, Arnout Van Messem, Wesley De Neve, Hyunjin Shim
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 310 (2022)
Protein therapeutics play an important role in controlling the functions and activities of disease-causing proteins in modern medicine. Despite protein therapeutics having several advantages over traditional small-molecule therapeutics, further devel
Externí odkaz:
https://doaj.org/article/d5e7dce7443945bf81841714c4d21da6
Autor:
Ho-min Park, Espoir Kabanga, Dongin Moon, Minjae Chung, Jiwon Im, Yujin Kim, Arnout Van Messem, Wesley De Neve
Parkinson’s disease is a neurodegenerative disorder that affects millions of people worldwide, posing significant challenges for diagnosis and treatment. This study presents a machine learning pipeline for identifying candidate biomarker proteins a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84945a0a4edaa21efb98a950c202c565
https://doi.org/10.1101/2023.05.18.541380
https://doi.org/10.1101/2023.05.18.541380
Autor:
Ho-min Park, Jongbum Won, Yunseol Park, Esla Timothy Anzaku, Joris Vankerschaver, Arnout Van Messem, Wesley De Neve, Hyunjin Shim
MotivationCRISPR-Cas-Docker is a web server forin silicodocking experiments with CRISPR RNAs (crRNAs) and Cas proteins. This web server aims at providing experimentalists with the optimal crRNA-Cas pair predicted computationally when prokaryotic geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce84166213a0d511856013064f87fbeb
https://doi.org/10.1101/2023.01.04.522819
https://doi.org/10.1101/2023.01.04.522819