Illness severity assessment of older adults in critical illness using machine learning (ELDER-ICU): an international multicentre study with subgroup bias evaluation

Autor: Xiaoli Liu, PhD, Pan Hu, MS, Wesley Yeung, MBBS, Zhongheng Zhang, ProfMD, Vanda Ho, MB BChir, Chao Liu, MD, Clark Dumontier, ProfMD MPH, Patrick J Thoral, MD, Zhi Mao, ProfMD, Desen Cao, PhD, Roger G Mark, ProfPhD, Zhengbo Zhang, ProfPhD, Mengling Feng, ProfPhD, Deyu Li, ProfPhD, Leo Anthony Celi, ProfMD MPH

Publikováno v: The Lancet: Digital Health, Vol 5, Iss 10, Pp e657-e667 (2023)

Summary: Background: Comorbidity, frailty, and decreased cognitive function lead to a higher risk of death in elderly patients (more than 65 years of age) during acute medical events. Early and accurate illness severity assessment can support appropr

Externí odkaz: https://doaj.org/article/7b768fd63ff84ec98768758e04599e10

Clinically Interpretable Machine Learning Models for Early Prediction of Mortality in Older Patients with Multiple Organ Dysfunction Syndrome

Autor: Xiaoli Liu, Clark DuMontier, Pan Hu, Chao Liu, Wesley Yeung, Zhi Mao, Vanda Ho, Patrick J Thoral, Po-Chih Kuo, Jie Hu, Deyu Li, Desen Cao, Roger G Mark, FeiHu Zhou, Zhengbo Zhang, Leo Anthony Celi

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences, 78(4), 718-726. Oxford University Press
J Gerontol A Biol Sci Med Sci
Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 78(4), 718-726. Oxford University Press
Liu, X, DuMontier, C, Hu, P, Liu, C, Yeung, W, Mao, Z, Ho, V, Thoral, P J, Kuo, P-C, Hu, J, Li, D, Cao, D, Mark, R G, Zhou, F, Zhang, Z & Celi, L A 2023, ' Clinically Interpretable Machine Learning Models for Early Prediction of Mortality in Older Patients with Multiple Organ Dysfunction Syndrome : An International Multicenter Retrospective Study ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 78, no. 4, pp. 718-726 . https://doi.org/10.1093/gerona/glac107

Background Multiple organ dysfunction syndrome (MODS) is associated with a high risk of mortality among older patients. Current severity scores are limited in their ability to assist clinicians with triage and management decisions. We aim to develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1ad99a9aaecaaf1970884b24e35764
https://doi.org/10.1093/gerona/glac107

Blood pressure trend in hospitalized adult dengue patients.

Autor: Wesley Yeung, David Chien Boon Lye, Tun-Linn Thein, Yirong Chen, Yee-Sin Leo

Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0235166 (2020)

BACKGROUND:Monitoring of blood pressure is an important part of management of dengue illness. Large scale studies of temporal trend of blood pressure in adult dengue are lacking. In this study, we examined the differences in time trend of systolic (S

Externí odkaz: https://doaj.org/article/b5ccdff30ce54e57849332199864830a

Factors influencing protective behaviours during haze episodes in Singapore: A population-based study

Autor: Ryan K J Lee, Wesley Yeung, Claudia Y.X. Chong, Kai Yun Ang, Nigel J M Fong, Bee Choo Tai, Kennedy Yao Yi Ng, Yun Hao Leong, Julia Ann-Lee, Sai Liang, Jie Xin Lim, Xinqi Look, Alex Hui Chung Lua, Ka Lon Sou, Amanda Chin, Judy Gek Khim Sng, Cheryl Jia Ling Lie

Publikováno v: Annals of the Academy of Medicine, Singapore. 50:514-526

Introduction: Haze is a recurrent problem in Southeast Asia. Exposure to haze is linked to ophthalmic, respiratory and cardiovascular diseases, and mortality. In this study, we investigated the role of demographic factors, knowledge and perceived ris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15558b853822d324d8a85f69221a89bb
https://doi.org/10.47102/annals-acadmedsg.2020614

Predicting mortality, thrombus recurrence and persistence in patients with post-acute myocardial infarction left ventricular thrombus

Autor: Ching-Hui Sia, Benjamin Yong-Qiang Tan, Joshua P. Loh, Leonard Leong-Litt Yeo, Tom J. Pollard, Wesley Yeung, Edgar Lik Wui Tay, Tiong-Cheng Yeo, Aloysius Sheng-Ting Leow, Rajinderdeep Kaur, Mark Y. Chan

Publikováno v: Journal of Thrombosis and Thrombolysis. 52:654-661

Left ventricular thrombus (LVT) is a common complication of acute myocardial infarction and is associated with morbidity from embolic complications. Predicting which patients will develop death or persistent LVT despite anticoagulation may help clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::028f0f9cf7720ba86708ea6dba74aa7d
https://doi.org/10.1007/s11239-020-02368-1