Single-cell multi-omics analysis reveals candidate therapeutic drugs and key transcription factor specifically for the mesenchymal subtype of glioblastoma.

Autor: Yang, Yufan^1,2 (AUTHOR), Liu, Ziyuan^2,3 (AUTHOR), Wei, Yerong^1,2 (AUTHOR), He, Shuai^2,3 (AUTHOR), Gu, Ancheng^1,2 (AUTHOR), Li, Zhiyong⁴ (AUTHOR), Li, Jianlong⁵ (AUTHOR) jianlongyx@163.com, Xu, Zhongyuan^1,2 (AUTHOR) nflcyljd@smu.edu.cn, Cen, Bohong^1,2,6 (AUTHOR) cenbohong22@i.smu.edu.cn

Publikováno v: Cell & Bioscience. 12/20/2024, Vol. 14 Issue 1, p1-21. 21p.

Deciphering gene expression patterns using large-scale transcriptomic data and its applications.

Autor: Chen, Shunjie¹ (AUTHOR), Wang, Pei^1,2 (AUTHOR) wangpei@henu.edu.cn, Guo, Haiping¹ (AUTHOR), Zhang, Yujie¹ (AUTHOR)

Publikováno v: Briefings in Bioinformatics. Nov2024, Vol. 25 Issue 6, p1-17. 17p.

Reactivation of the pluripotency program precedes formation of the cranial neural crest.

Autor: Zalc A; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Gulati GS; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Wesche DJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Daszczuk P; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Swigut T; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA., Wysocka J; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. wysocka@stanford.edu.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA 94305, USA.; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2021 Feb 05; Vol. 371 (6529).

Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process.

Autor: Zhang, Cangang^1,2,3 (AUTHOR), Ren, Tao^4,5 (AUTHOR), Zhao, Xiaofan⁶ (AUTHOR), Su, Yanhong^1,2,3 (AUTHOR), Wang, Qianhao^1,2,3 (AUTHOR), Zhang, Tianzhe^1,2,3 (AUTHOR), He, Boxiao⁷ (AUTHOR), Chen, Yabing⁸ (AUTHOR), Wu, Ling-Yun^4,5 (AUTHOR), Sun, Lina^1,2,3 (AUTHOR) lina.sun@xjtu.edu.cn, Zhang, Baojun^1,2,3 (AUTHOR) bj.zhang@mail.xjtu.edu.cn, Xia, Zheng^6,9,10 (AUTHOR) xiaz@ohsu.edu

Publikováno v: Immunity & Ageing. 10/24/2024, Vol. 21 Issue 1, p1-21. 21p.

A two-step strategy to expand primary human hepatocytes in vitro with efficient metabolic and regenerative capacities.

Autor: Xie, Huangfan^1,2 (AUTHOR), Li, Guangya³ (AUTHOR), Fu, Yunxi^1,2 (AUTHOR), Jiang, Nan¹ (AUTHOR), Yi, Simeng¹ (AUTHOR), Kong, Xi¹ (AUTHOR), Shi, Jihang⁴ (AUTHOR), Yin, Shigang^1,2 (AUTHOR), Peng, Jianhua^1,2 (AUTHOR), Jiang, Yong^1,2 (AUTHOR), Lu, Shichun⁵ (AUTHOR) lsc620213@aliyun.com, Deng, Hongkui³ (AUTHOR) hongkui_deng@pku.edu.cn, Xie, Bingqing^1,2 (AUTHOR) bingqingxie@swmu.edu.cn

Publikováno v: Stem Cell Research & Therapy. 9/4/2024, Vol. 15 Issue 1, p1-17. 17p.