Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Wes Sisson"'
Autor:
Stephen E. Webber, Amit M. Shah, Kevin R. Steffy, James R. Appleman, Alan X. Xiang, Robert M. Aust, Thomas Doundoulakis, Richard E. Showalter, Klaus B. Simonsen, William T. Biller, Virginia N. Banh, Wes Sisson, Ricardo Lira, Konstantinos A. Agrios
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6797-6800
Based upon observations from our initial findings, additional myxopyronin B analogs have been prepared and tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against Escherichia coli and Staphyloco
Autor:
Stephen E. Webber, Amit M. Shah, Richard E. Showalter, Alan X. Xiang, Wes Sisson, Robert M. Aust, Ricardo Lira, Klaus B. Simonsen, James R. Appleman, Konstantinos A. Agrios, Thomas Doundoulakis
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(22)
A series of myxopyronin B analogs has been prepared via a convergent synthetic route and were tested for in vitro inhibitory activity against DNA-dependent RNA polymerase and antibacterial activity against E. coli and S. aureus. The parent lead compo
Publikováno v:
Biochemistry. 35(16)
The single-chain 28 kDa human cytomegalovirus (HCMV) protease catalytic domain containing the A143Q mutation has been kinetically and conformationally characterized. The specific activity of the HCMV A143Q protease (HCMVp) increases as the protease c