Pharmacokinetics of oral hydrocortisone - Results and implications from a randomized controlled trial

Autor: Werumeus Buning, Jorien, Touw, Daan J., Brummelman, Pauline, Dullaart, Robin P.F., van den Berg, Gerrit, van der Klauw, Melanie M., Kamp, Jasper, Wolffenbuttel, Bruce H.R., van Beek, André P.

Publikováno v: In Metabolism June 2017 71:7-16

The effects of two different doses of hydrocortisone on cognition in patients with secondary adrenal insufficiency – Results from a randomized controlled trial

Autor: Werumeus Buning, Jorien, Brummelman, Pauline, Koerts, Janneke, Dullaart, Robin P.F., van den Berg, Gerrit, van der Klauw, Melanie M., Tucha, Oliver, Wolffenbuttel, Bruce H.R., van Beek, André P.

Publikováno v: In Psychoneuroendocrinology May 2015 55:36-47

Somatosensory function in patients with secondary adrenal insufficiency treated with two different doses of hydrocortisone-Results from a randomized controlled trial.

Autor: Jorien Werumeus Buning, Karl-Heinz Konopka, Pauline Brummelman, Janneke Koerts, Robin P F Dullaart, Gerrit van den Berg, Melanie M van der Klauw, Oliver Tucha, Bruce H R Wolffenbuttel, André P van Beek

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0180326 (2017)

Low cortisol levels are associated with several functional pain syndromes. In patients with secondary adrenal insufficiency (SAI), the lack in endogenous cortisol production is substituted by the administration of oral hydrocortisone (HC). Our previo

Externí odkaz: https://doaj.org/article/ea2e0ae6c7b44081a07b07b4c0ad96f1

Population pharmacokinetics and probability of target attainment of different dosing regimens of ceftazidime in critically ill patients with a proven or suspected pseudomonas aeruginosa infection

Autor: Natalia M. Lechner, Reinier M. van Hest, Nicole P. Juffermans, Paul W. G. Elbers, Menno D. de Jong, Margriet Schokkin, Ron A. A. Mathôt, Annabel Werumeus Buning, Caspar J. Hodiamont

Publikováno v: Antibiotics (Basel, Switzerland), 10(6):612. Multidisciplinary Digital Publishing Institute (MDPI)
Antibiotics, Vol 10, Iss 612, p 612 (2021)
Buning, A W, Hodiamont, C J, Lechner, N M, Schokkin, M, Elbers, P W G, Juffermans, N P, Mathôt, R A A, de Jong, M D & van Hest, R M 2021, ' Population pharmacokinetics and probability of target attainment of different dosing regimens of ceftazidime in critically ill patients with a proven or suspected pseudomonas aeruginosa infection ', Antibiotics, vol. 10, no. 6, 612 . https://doi.org/10.3390/antibiotics10060612
Antibiotics, 10(6):612. Multidisciplinary Digital Publishing Institute
Antibiotics
Volume 10
Issue 6

Altered pharmacokinetics (PK) of hydrophilic antibiotics in critically ill patients is common, with possible consequences for efficacy and resistance. We aimed to describe ceftazidime population PK in critically ill patients with a proven or suspecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0eee1d9a6382a7c341a4de60f26ca7c
http://www.scopus.com/inward/record.url?scp=85107205226&partnerID=8YFLogxK

Hydrocortisone Affects Fatigue and Physical Functioning Through Metabolism of Tryptophan

Autor: Ido P. Kema, Freek J. H. Sorgdrager, Elske Bos, Jorien Werumeus Buning, André P van Beek

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 103(9), 3411-3419. ENDOCRINE SOC

Context: Hydrocortisone (HC) treatment influences health-related quality of life (HRQOL) in secondary adrenal insufficiency (AI). Glucocorticoids regulate tryptophan metabolism through the kynurenine pathway which modulates mood and energy homeostasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5a9739282ccf4b08f572b8e6fa5acd
https://doi.org/10.1210/jc.2018-00582