Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Weronika Maksymiuk"'
1
Akademický článek
Vitamin B6 inhibits activity of Helicobacter pylori adenylosuccinate synthetase and growth of reference and clinical, antibiotic-resistant H. pylori strains
Autor: Marta Ilona Wojtyś, Weronika Maksymiuk, Marta Narczyk, Ante Bubić, Ivana Leščić Ašler, Paweł Krzyżek, Grażyna Gościniak, Elżbieta Katarzyna Jagusztyn-Krynicka, Agnieszka Bzowska
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
The current therapies against gastric pathogen Helicobacter pylori are ineffective in over 20% of patients. Enzymes belonging to the purine salvage pathway are considered as novel drug targets in this pathogen. Therefore, the main aim of the current
Externí odkaz: https://doaj.org/article/d49a28023d5d4282a32dff07929d534e
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2
Akademický článek
Reactive Gliosis in Neonatal Disorders: Friend or Foe for Neuroregeneration?
Autor: Justyna Gargas, Justyna Janowska, Paulina Gebala, Weronika Maksymiuk, Joanna Sypecka
Publikováno v: Cells, Vol 13, Iss 2, p 131 (2024)
A developing nervous system is particularly vulnerable to the influence of pathophysiological clues and injuries in the perinatal period. Astrocytes are among the first cells that react to insults against the nervous tissue, the presence of pathogens
Externí odkaz: https://doaj.org/article/de1f55e6b35b4b2ab58101ff32315c8c
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3
The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site
Autor: Ante Bubić, Marta Narczyk, Ana Petek, Marta Ilona Wojtyś, Weronika Maksymiuk, Beata Wielgus-Kutrowska, Maria Winiewska-Szajewska, Tea Pavkov-Keller, Branimir Bertoša, Zoran Štefanić, Marija Luić, Agnieszka Bzowska, Ivana Leščić Ašler
Publikováno v: International Journal of Biological Macromolecules. 226:37-50
Purine nucleotide synthesis is realised only through the salvage pathway in pathogenic bacterium Helicobacter pylori. Therefore, the enzymes of this pathway, among them also the adenylosuccinate synthetase (AdSS), present potential new drug targets.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a08c448faeb8e035a12494a0af5dc71
https://doi.org/10.1016/j.ijbiomac.2022.12.001
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Plný text Recenzováno Digitální knihovna AV ČR
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