Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding

Autor: Alina Kulakova, Dillen Augustijn, Inas El Bialy, Lorenzo Gentiluomo, Maria Laura Greco, Stefan Hervø-Hansen, Sowmya Indrakumar, Sujata Mahapatra, Marcello Martinez Morales, Christin Pohl, Marco Polimeni, Aisling Roche, Hristo L. Svilenov, Andreas Tosstorff, Matja Zalar, Robin Curtis, Jeremy P. Derrick, Wolfgang Frieß, Alexander P. Golovanov, Mikael Lund, Allan Nørgaard, Tarik A. Khan, Günther H. J. Peters, Alain Pluen, Dierk Roessner, Werner W. Streicher, Christopher F. van der Walle, Jim Warwicker, Shahid Uddin, Gerhard Winter, Jens Thostrup Bukrinski, Åsmund Rinnan, Pernille Harris

Publikováno v: Molecular Pharmaceutics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b30e33ef72e37b5def8fabb536c102a3
https://doi.org/10.1021/acs.molpharmaceut.3c00013

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.

Autor: Huaying Zhao, Rodolfo Ghirlando, Carlos Alfonso, Fumio Arisaka, Ilan Attali, David L Bain, Marina M Bakhtina, Donald F Becker, Gregory J Bedwell, Ahmet Bekdemir, Tabot M D Besong, Catherine Birck, Chad A Brautigam, William Brennerman, Olwyn Byron, Agnieszka Bzowska, Jonathan B Chaires, Catherine T Chaton, Helmut Cölfen, Keith D Connaghan, Kimberly A Crowley, Ute Curth, Tina Daviter, William L Dean, Ana I Díez, Christine Ebel, Debra M Eckert, Leslie E Eisele, Edward Eisenstein, Patrick England, Carlos Escalante, Jeffrey A Fagan, Robert Fairman, Ron M Finn, Wolfgang Fischle, José García de la Torre, Jayesh Gor, Henning Gustafsson, Damien Hall, Stephen E Harding, José G Hernández Cifre, Andrew B Herr, Elizabeth E Howell, Richard S Isaac, Shu-Chuan Jao, Davis Jose, Soon-Jong Kim, Bashkim Kokona, Jack A Kornblatt, Dalibor Kosek, Elena Krayukhina, Daniel Krzizike, Eric A Kusznir, Hyewon Kwon, Adam Larson, Thomas M Laue, Aline Le Roy, Andrew P Leech, Hauke Lilie, Karolin Luger, Juan R Luque-Ortega, Jia Ma, Carrie A May, Ernest L Maynard, Anna Modrak-Wojcik, Yee-Foong Mok, Norbert Mücke, Luitgard Nagel-Steger, Geeta J Narlikar, Masanori Noda, Amanda Nourse, Tomas Obsil, Chad K Park, Jin-Ku Park, Peter D Pawelek, Erby E Perdue, Stephen J Perkins, Matthew A Perugini, Craig L Peterson, Martin G Peverelli, Grzegorz Piszczek, Gali Prag, Peter E Prevelige, Bertrand D E Raynal, Lenka Rezabkova, Klaus Richter, Alison E Ringel, Rose Rosenberg, Arthur J Rowe, Arne C Rufer, David J Scott, Javier G Seravalli, Alexandra S Solovyova, Renjie Song, David Staunton, Caitlin Stoddard, Katherine Stott, Holger M Strauss, Werner W Streicher, John P Sumida, Sarah G Swygert, Roman H Szczepanowski, Ingrid Tessmer, Ronald T Toth, Ashutosh Tripathy, Susumu Uchiyama, Stephan F W Uebel, Satoru Unzai, Anna Vitlin Gruber, Peter H von Hippel, Christine Wandrey, Szu-Huan Wang, Steven E Weitzel, Beata Wielgus-Kutrowska, Cynthia Wolberger, Martin Wolff, Edward Wright, Yu-Sung Wu, Jacinta M Wubben, Peter Schuck

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0126420 (2015)

Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of macromolecules and their complexes, reporting on their size and shape in free solution. The purpose o

Externí odkaz: https://doaj.org/article/3bd91e8f42734f39965350067490e003

Advances in the analysis of conformational transitions in peptides using differential scanning calorimetry

Autor: Werner W, Streicher, George I, Makhatadze

Publikováno v: Methods in molecular biology (Clifton, N.J.). 350

Differential scanning calorimetry can measure the heat capacity of a protein/peptide solution over a range of temperatures at constant pressure, which is used to determine the enthalpy function of the system. There are several experimental factors th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1399ab44343b6edfe888c71a42e3216e
https://pubmed.ncbi.nlm.nih.gov/16957320

Albumin-neprilysin fusion protein: understanding stability using small angle X-ray scattering and molecular dynamic simulations.

Autor: Kulakova, Alina¹, Indrakumar, Sowmya¹, Sønderby Tuelung, Pernille¹, Mahapatra, Sujata², Streicher, Werner W.², Peters, Günther H. J.¹, Harris, Pernille¹ ph@kemi.dtu.dk

Publikováno v: Scientific Reports. 6/22/2020, Vol. 10 Issue 1, p1-13. 13p.

Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition.

Autor: Bohr, Søren S.-R.^1,2, Lund, Philip M.^1,2, Kallenbach, Amalie S.^1,2, Pinholt, Henrik^1,2, Thomsen, Johannes^1,2, Iversen, Lars³, Svendsen, Allan³, Christensen, Sune M.³, Hatzakis, Nikos S.^1,2 hatzakis@nano.ku.dk

Publikováno v: Scientific Reports. 11/7/2019, Vol. 9 Issue 1, pN.PAG-N.PAG. 1p.