Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Werner Steimer"'
Autor:
Johannes Matthaei, Jürgen Brockmöller, Werner Steimer, Konstanze Pischa, Stefan Leucht, Maria Kullmann, Ole Jensen, Typhaine Ouethy, Mladen Vassilev Tzvetkov, Muhammad Rafehi
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The tricyclic antidepressant amitriptyline is frequently prescribed but its use is limited by its narrow therapeutic range and large variation in pharmacokinetics. Apart from interindividual differences in the activity of the metabolising enzymes cyt
Externí odkaz:
https://doaj.org/article/9ae58c175f44436db83dbd9a1c9a18d2
Autor:
Marion Ortner, Marion Stange, Heike Schneider, Charlotte Schroeder, Katharina Buerger, Claudia Müller, Bianca Dorn, Oliver Goldhardt, Janine Diehl-Schmid, Hans Förstl, Werner Steimer, Timo Grimmer
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundAcetylcholinesterase inhibitors (AChE-I) are recommended for the treatment of cognitive symptoms but also of behavioral and psychological symptoms in dementia. They are widely used not only in Alzheimer's disease, but also in other forms of
Externí odkaz:
https://doaj.org/article/729c09c05c0c45e7ad561376a11c3f6f
Autor:
Charlotte Schröder, Werner Steimer
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192414 (2018)
Epigenetics is believed to provide great chances for a better understanding of the development and treatment of many diseases where the analysis of genomic DNA has so far failed to provide conclusive answers. Methylcytosine is a frequently used quant
Externí odkaz:
https://doaj.org/article/ddb0dc91defe48ca99e2f9b569aa28f3
Autor:
Maike Scherf-Clavel, Pierre Baumann, Xenia M. Hart, Heike Schneider, Georgios Schoretsanitis, Werner Steimer, Gerald Zernig, Gabriela Zurek
Publikováno v:
Therapeutic Drug Monitoring.
Publikováno v:
Psychopharmacology.
Rationale Weight gain is a frequent side effect of treatment with SGAs (second-generation antipsychotics) and a leading cause for nonadherence. Several candidate genes have been identified that could influence the amount of AIWG (antipsychotic-induce
Autor:
Mark W. Linder, Katarina Baluchova, Deborah A. Payne, Aldo Vacaflores Salinas, Parviz Ahmad-Nejad, Jim F. Huggett, Werner Steimer, Tester F. Ashavaid, Kathryn A. Harris
Publikováno v:
Clinica Chimica Acta. 519:239-246
The development and performance of molecular genetic assays has required increasingly complex quality assurance in recent years and continues to pose new challenges. Quality management officers, as well as academic and technical personnel are confron
Autor:
Marja-Liisa Dahl, Nicolas Ansermot, Séverine Crettol, H. Uchida, Peter Riederer, Andreas Conca, E. Kim, Christoph Hiemke, S. Suzen, Margareta Reis, Olav Spigset, Oliver D. Howes, Edoardo Spina, Emmanuelle Corruble, J. de Leon, J. H. Meyer, Julia C. Stingl, Pierre Baumann, Stefan Unterecker, H. G. Ruhe, Frederik Vandenberghe, Daniel J. Müller, Gerhard Gründer, H. Mulder, Werner Steimer, Rupert Lanzenberger, B. Stegman, Christine Greiner, Rainald Moessner, Chin B. Eap
Publikováno v:
World Journal of Biological Psychiatry, 22, 561-628
World Journal of Biological Psychiatry, 22, 8, pp. 561-628
World Journal of Biological Psychiatry
Eap, C B, Gründer, G, Baumann, P, Ansermot, N, Conca, A, Corruble, E, Crettol, S, Dahl, M L, de Leon, J, Greiner, C, Howes, O, Kim, E, Lanzenberger, R, Meyer, J H, Moessner, R, Mulder, H, Müller, D J, Reis, M, Riederer, P, Ruhe, H G, Spigset, O, Spina, E, Stegman, B, Steimer, W, Stingl, J, Suzen, S, Uchida, H, Unterecker, S, Vandenberghe, F & Hiemke, C 2021, ' Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests) : focus on antidepressants ', World Journal of Biological Psychiatry, vol. 22, no. 8, pp. 561-628 . https://doi.org/10.1080/15622975.2021.1878427
World Journal of Biological Psychiatry, 22, 8, pp. 561-628
World Journal of Biological Psychiatry
Eap, C B, Gründer, G, Baumann, P, Ansermot, N, Conca, A, Corruble, E, Crettol, S, Dahl, M L, de Leon, J, Greiner, C, Howes, O, Kim, E, Lanzenberger, R, Meyer, J H, Moessner, R, Mulder, H, Müller, D J, Reis, M, Riederer, P, Ruhe, H G, Spigset, O, Spina, E, Stegman, B, Steimer, W, Stingl, J, Suzen, S, Uchida, H, Unterecker, S, Vandenberghe, F & Hiemke, C 2021, ' Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests) : focus on antidepressants ', World Journal of Biological Psychiatry, vol. 22, no. 8, pp. 561-628 . https://doi.org/10.1080/15622975.2021.1878427
Contains fulltext : 238693.pdf (Publisher’s version ) (Open Access) Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and
Autor:
Julia C. Stingl, Georgios Schoretsanitis, Manfred Gerlach, Bernd Schoppek, Gabriela Zurek, Werner Steimer, Jose de Leon, Niels Bergemann, Alois Saria, E. Jaquenoud-Sirot, Andreas Conca, Karin Egberts, Markus J. Schwarz, Thomas Messer, Matthias Müller, Manfred Uhr, Sven Ulrich, Ursula Havemann-Reinecke, Carlos López-Jaramillo, Michael Paulzen, Pierre Baumann, Gerhard Gründer, Stefan Unterecker, Margarete Silva Gracia, Benedikt Stegmann, E Haen, Ger Janssen, Christine Greiner, Peter Riederer, Gudrun Hefner, Gerd Laux, Ana M. Díaz-Zuluaga, R. Waschgler, Rainald Mössner, Gerald Zernig, Renate Helmer, Gabriel Eckermann, Bruno Pfuhlmann, Hans-Willi Clement, Christoph Hiemke, Katharina Domschke
Publikováno v:
Psiquiatría Biológica. 27:83-95
Resumen Objetivo La Monitorizacion Terapeutica de Drogas (llamada en ingles TDM: therapeutic drug monitoring) combina la cuantificacion de las concentraciones de medicamentos en la sangre, la interpretacion farmacologica y las directrices de tratamie
Autor:
Timo Grimmer, Marion Ortner, Katharina Buerger, Claudia Müller, Heike Schneider, Janine Diehl-Schmid, Marion Stange, Werner Steimer, Felix Müller-Sarnowski, Hans Förstl, Charlotte Schröder
Publikováno v:
Drug Design, Development and Therapy. 14:3251-3262
Background The efficacy of acetylcholinesterase inhibitors (AChE-I) might depend on blood concentration. While rivastigmine metabolism is independent of the cytochrome P450 system, its isoenzymes, especially CYP2D6, metabolize donepezil. CYP2D6 polym
Publikováno v:
Therapeutic drug monitoring. 44(1)
For many antibiotics, the convenient one-fits-all dosing regimen had to be abandoned. Owing to highly variable pharmacokinetics, therapeutic drug monitoring has become an indispensable prerequisite. It is based on a suitable measuring method, sample