Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Werner Stegmann"'
Autor:
Petra Jaeckel, Gerhard P. Schwall, Martina Klemm-Manns, Wojciech Wozny, Margino Steemans, Slobodan Poznanovic, Horst Spielmann, Helmut Zengerling, Tina C. Stummann, Karlfried Groebe, Rainer Schöpf, André Schrattenholz, Werner Stegmann, Chaturvedala Sastri, Andrea Seiler, Annelieke K. Peters, Katrin Hayess
Publikováno v:
Reproductive Toxicology. 30:121-130
Novel molecular content for fast in vitro strategies in the context of safety tests concerning developmental toxicity has a potential to substantially reduce animal experiments according to the "3R" concept (Reduce/Refine/Replace). Here we present an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70f8202518690ba22e1503784d398cd
https://doi.org/10.1016/j.reprotox.2010.05.006
https://doi.org/10.1016/j.reprotox.2010.05.006
Autor:
Michael Burnet, Karlfried Groebe, Gerhard P. Schwall, Martina Klemm, Werner Stegmann, Vukic Soskic, Slobodan Poznanović, Helmut Zengerling, Tassula Proikas-Cezanne, André Schrattenholz, Rainer Schoepf
Publikováno v:
Journal of Proteome Research. 7:2262-2269
In a drug reprofiling attempt, we explored novel neuroprotective properties of 4-azasteroids by synthesizing chemical affinity tags capturing adenine nucleotide translocator-1, as a potential target. Dutasteride inhibits the mitochondrial transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa71c179fa11cfdde345e5b5db241dc
https://doi.org/10.1021/pr700686x
https://doi.org/10.1021/pr700686x
Autor:
André Schrattenholz, James T. Summersgill, Werner Stegmann, Matthias Maass, Michael Przybylski, Iuliana Susnea, Albrecht Wendel, Jan Rupp, Sebastian Bunk, Corinna Hermann
Publikováno v:
The Journal of Immunology. 180:5490-5498
The controversial discussion about the role of Chlamydia pneumoniae in atherosclerosis cannot be solved without a reliable diagnosis that allows discrimination between past and persistent infections. Using a proteomic approach and immunoblotting with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0f514f62b6ece954e2a1b12af6e0ee
https://doi.org/10.4049/jimmunol.180.8.5490
https://doi.org/10.4049/jimmunol.180.8.5490
Autor:
Karlfried Groebe, Wojciech Wozny, Jorg Servos, Michael A. Cahill, Werner Stegmann, Gerhard P. Schwall, André Schrattenholz, Josef Vogt
Publikováno v:
Journal of Chromatography A. 1161:67-70
Living mice were subjected to whole body labeling by intravenous infusion of [(13)C]glucose as the sole carbon source. After 10 h infusion the mice were sacrificed, and liver proteins were separated by two-dimensional polyacrylamide gel electrophores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa488ce5994a8659420155091dc34e4
https://doi.org/10.1016/j.chroma.2007.04.019
https://doi.org/10.1016/j.chroma.2007.04.019
Autor:
Vukic Soskic, Gerhard P. Schwall, André Schrattenholz, Elke Nyakatura, Werner Stegmann, Slobodan Poznanovic
Publikováno v:
Journal of Proteome Research. 5:3453-3458
Serum and plasma are the major sources of human material for clinical molecular diagnostics and drug discovery. However, due to the high abundance of some proteins, of which serum albumin (SA) is most prominent, lower-abundance proteins often remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f635a9eaaa1df228e597a8108e72ac
https://doi.org/10.1021/pr060387q
https://doi.org/10.1021/pr060387q
Autor:
Christian Hunzinger, Werner Stegmann, Slobodan Poznanovic, Gerhard P. Schwall, André Schrattenholz
Publikováno v:
Journal of Chromatography A. 1123:170-181
In this article we evaluate methods used to reveal the molecular complexity, which is generated in biological samples by posttranslational modifications (PTM) of proteins. We show how distinct molecular differences on the level of phosphorylation sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4b6129fcc38aee162910f7e7e60705
https://doi.org/10.1016/j.chroma.2006.06.002
https://doi.org/10.1016/j.chroma.2006.06.002
Autor:
Werner Stegmann, André Schrattenholz, Tanja Fehm, Alfred Nordheim, Wojciech Wozny, Gerhard P. Schwall, Karl Sotlar, Raffael Kurek, Michael A. Cahill, Christian Hunzinger, Susan E. Clare, Diethelm Wallwiener, Chaturvedula Sastri, Slobodan Poznanovic, Hans Neubauer
Publikováno v:
ELECTROPHORESIS. 27:1840-1852
The presence of progesterone receptor (PR) in estrogen receptor (ER)-positive breast cancer is associated with a good prognosis, and indicates that tumors are likely to respond to tamoxifen. However, ER + /PR - tumors respond less well. To reveal the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62191eb2da2bf6aaa40ed4fa9406096
https://doi.org/10.1002/elps.200500739
https://doi.org/10.1002/elps.200500739
Autor:
Renate Burgemeister, Chaturvedula Sastri, Slobodan Poznanović, André Schrattenholz, Wojciech Wozny, Gerhard P. Schwall, Michael A. Cahill, Alexander Buchner, Rainer Gangnus, Christian Hunzinger, Werner Stegmann
Publikováno v:
Journal of Proteome Research. 4:2117-2125
We present a proof of principle study, using laser microdissection and pressure catapulting (LMPC) of two clinical tissue samples, each containing approximately 3.8 microg renal cell carcinoma protein and 3.8 microg normal kidney protein respectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0138a9e9ca91ffc20ad8ba8edfb37ef4
https://doi.org/10.1021/pr050218q
https://doi.org/10.1021/pr050218q
Autor:
André Schrattenholz, Michael A. Cahill, Martina Klemm, Wojciech Wozny, Werner Stegmann, Klaus Schroer
Publikováno v:
Journal of the Neurological Sciences. :261-267
The analysis of rapid changes of protein expression in living systems in response to insults requires rigorous methods of complexity reduction. To control dynamic pattern of hundreds or even thousands of protein isoforms, we applied a novel method of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5da44de5616c2aa8a0a55381d027d72
https://doi.org/10.1016/j.jns.2004.11.033
https://doi.org/10.1016/j.jns.2004.11.033
Autor:
Kerstin Hölzer, Michael A. Cahill, Wojciech Wozny, Slobodan Poznanovic, Josef Vogt, Klaus Schroer, André Schrattenholz, Helmut Matthies, Werner Stegmann, Christian Hunzinger, Gerhard P. Schwall
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:1283-1290
The new method of analysis of relative isotopologue abundances (ARIA) applied here is based on the evaluation of total isotope patterns of tryptic protein fragments measured by matrix-assisted laser desorption/ionisation time-of-flight mass spectrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ffd12c444f4376e41ad9ac375b6ae9
https://doi.org/10.1002/rcm.1046
https://doi.org/10.1002/rcm.1046