Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Werner Niederberger"'
Autor:
Marie-Claude Bastien, Wei Zhu, Robert B. Ettenger, Sharon M. Bartosh, Joelle Campestrini, Robert Schmouder, Werner Niederberger, Les Choi
Publikováno v:
Pediatric Transplantation. 9:780-787
This study aims to characterize the pharmacokinetics of mycophenolic acid (MPA) and its glucuronide metabolite (mycophenolic acid 7-O-glucuronide, MPAG) following single oral administration of enteric-coated mycophenolate sodium (EC-MPS, myfortic) at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820facab6eac5d1d0fc45b6497fdbf24
https://doi.org/10.1111/j.1399-3046.2005.00386.x
https://doi.org/10.1111/j.1399-3046.2005.00386.x
Autor:
Hitoshi Sato, Jerry Nedelman, Michel Lemaire, Steven B. Charnick, Ryosei Kawai, Werner Niederberger
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 23:217-229
Since the pioneering work of Haggard and Teorell in the first half of the 20th century, and of Bischoff and Dedrick in the late 1960s, physiologically based pharmacokinetic (PBPK) modeling has gone through cycles of general acceptance, and of healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::604d2fba6d0b3fc16ae4dbc60563211e
https://doi.org/10.1007/bf02354273
https://doi.org/10.1007/bf02354273
Autor:
Jean-Louis Steimer, Joost van Bree, Jerry Nedelman, Werner Niederberger, William T. Robinson, Francis L. S. Tse
Publikováno v:
Drug Information Journal. 28:263-279
In toxicology experiments in rodents, separate animals in satellite groups are routinely incorporated to assess the pharmacokinetic (toxicokinetic) characteristics of the drug. This approach has two major drawbacks: 1. limited or no individual exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c248edf6946421679db2767722a8ec79
https://doi.org/10.1177/009286159402800134
https://doi.org/10.1177/009286159402800134
Autor:
Laurent Vernillet, E A Mueller, Ronald Freiburghaus, Werner Niederberger, K Kutz, John M. Kovarik
Publikováno v:
Therapeutic drug monitoring. 16(5)
Several lines of evidence suggest that cyclosporine may undergo prehepatic metabolism, the possible contribution of which to the overall biotransformation of the drug is, however, unclear. A recently developed oral formulation of cyclosporine, Sandim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fae4a7c33756e62451bf7f364d9a570
https://pubmed.ncbi.nlm.nih.gov/7846753
https://pubmed.ncbi.nlm.nih.gov/7846753
Autor:
Werner Niederberger, Michel Lemaire, Malcolm Rowland, Ryosei Kawai, Armin Bruelisauer, Jean-Louis Steimer
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 22(5)
The immunosuppressant, SDZ IMM 125 (IMM), is a derivative of cyclosporin A (CyA). The disposition kinetics of IMM in plasma, blood cells, and various tissues of the rat was characterized by a physiologically based pharmacokinetic (PBPK) model; the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64d26588b1892c87bf89989bbea581d
https://pubmed.ncbi.nlm.nih.gov/7791036
https://pubmed.ncbi.nlm.nih.gov/7791036
Autor:
Erich Nüesch, Jean-Louis Steimer, Jean-Philippe Jais, Werner Niederberger, Robert Laplanche, Bernard Fertil
Publikováno v:
Clinical pharmacology and therapeutics. 50(1)
Drug level monitoring during routine clinical visits in the course of phase III trials provides a means to document pharmacokinetic variability in a patient population. Such a pharmacokinetic screen was performed for the new calcium antagonist isradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380e1dc6c694b88dbe18775867eaeec3
https://pubmed.ncbi.nlm.nih.gov/1830252
https://pubmed.ncbi.nlm.nih.gov/1830252
Autor:
Joachim Seelig, Werner Niederberger
Publikováno v:
Biochemistry. 13:1585-1588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2078d4cbf2b5aeb3346441d9e36a4c77
https://doi.org/10.1021/bi00705a005
https://doi.org/10.1021/bi00705a005
Autor:
Joachim Seelig, Werner Niederberger
Publikováno v:
Journal of the American Chemical Society. 96:2069-2072
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda82675ef3655791644b632ebac9356
https://doi.org/10.1021/ja00814a014
https://doi.org/10.1021/ja00814a014
Publikováno v:
Biochemistry. 14:3647-3652
The conformation and motion of the choline head group in lipid bilayers above and below the gel-to-liquid crystal transition point are studied by means of deuterium and phosphorus magnetic resonance. For this purpose dipalmitoyl-3-sn-phosphatidylchol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750538b483d52a128b93cedf54a12197
https://doi.org/10.1021/bi00687a021
https://doi.org/10.1021/bi00687a021
Autor:
Werner Niederberger, Yves M. Tricot
Publikováno v:
Helvetica Chimica Acta. 67:1033-1039
Linear relationships between the inverse of the quadrupolar coupling constant, 1/χ and the asymmetry parameter η are obtained for the 7O-nucleus of acetone oriented in four different nematic phases, using the information contained in 1H- and 17O-NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::641f914056eefece24d7c161e77606de
https://doi.org/10.1002/hlca.19840670416
https://doi.org/10.1002/hlca.19840670416