Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Werner Hofheinz"'
Autor:
Robert G. Ridley, Raffaello Masciadri, Werner Hofheinz, Hisao Shimada, Hugues Matile, Tomoko Satoh, Arnulf Dorn, Michiko Kitsuji-Shirane, Manfred Kansy, Yae Kurosawa
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:2638-2644
Hematin polymerization is a parasite-specific process that enables the detoxification of heme following its release in the lysosomal digestive vacuole during hemoglobin degradation, and represents both an essential and a unique pharmacological drug t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3caf2c1f59dc01a1e938960ed83645
https://doi.org/10.1128/aac.44.10.2638-2644.2000
https://doi.org/10.1128/aac.44.10.2638-2644.2000
Autor:
Werner Hofheinz, Robert A. Blouin, Steve Shedlofsky, Klaus Stoeckel, Jean Paul Laneury, Patrick Duchene
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:2602-2606
The levels of degradation of cefetamet pivoxil (CAT), cefuroxime axetil (CAE), and cefpodoxime proxetil (CPD) in 0.6 M phosphate buffer (pH 7.4) and human intestinal juice (pH 7.4) at 37°C over 24 h were compared. Significant differences in the time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434a9f51d8a57c2ef245ba70529bd4f2
https://doi.org/10.1128/aac.42.10.2602
https://doi.org/10.1128/aac.42.10.2602
Autor:
E Gocke, W Peters, M Csato, A Thomas, Arnulf Dorn, A Guenzi, Raffaello Masciadri, M A Girometta, Werner Hofheinz, F P Theil, Wolfgang F. Richter, Robert G. Ridley, Catherine Jaquet, Hugues Matile, Werner Leupin, J M Potthast, H Urwyler
Publikováno v:
Antimicrobial Agents and Chemotherapy, 3, 41, 677-686
The S,S enantiomer of the bisquinoline trans-N1,N2-bis(7-chloroquinolin-4-yl)cyclohexane-1,2-diamine, Ro 47-7737, is significantly more potent against chloroquine-resistant Plasmodium falciparum than the R,R enantiomer and the previously described ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8148cea27675958018f50180a1758f
http://resolver.tudelft.nl/uuid:81a63337-a38d-4b57-9e81-cb5e6b5bc878
http://resolver.tudelft.nl/uuid:81a63337-a38d-4b57-9e81-cb5e6b5bc878
Autor:
Arnulf Dorn, W Peters, Wolfgang F. Richter, S Thaithong, Walter Huber, M A Girometta, Raffaello Masciadri, Synese Jolidon, Werner Hofheinz, A Guenzi, H Urwyler, Catherine Jaquet, Robert G. Ridley, Hugues Matile
Publikováno v:
Scopus-Elsevier
We have synthesized several 4-aminoquinolines with shortened side chains that retain activity against chloroquine-resistant isolates of Plasmodium falciparum malaria (W. Hofheinz, C. Jaquet, and S. Jolidon, European patent 94116281.0, June 1995). We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c09691fa59018b0603f0c165f363207
https://pubmed.ncbi.nlm.nih.gov/8843292
https://pubmed.ncbi.nlm.nih.gov/8843292
Autor:
Werner Hofheinz, Peter Schönholzer
Publikováno v:
Helvetica Chimica Acta. 60:1367-1370
Ircinianin (2), a new furano-sesterterpenetertronic acid, has been isolated from a marine sponge of the genus Ircinia. Structure 2 has been established by X-ray diffraction methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf56ff306dfcbbf6860901aacb852e
https://doi.org/10.1002/hlca.19770600425
https://doi.org/10.1002/hlca.19770600425
Autor:
Werner Hofheinz, Willi E. Oberhänsli
Publikováno v:
Helvetica Chimica Acta. 60:660-669
Dysidin, a novel chlorine containing natural product from the sponge Dysidea herbacea Dysidin (1) has been isolated from the marine sponge Dysidea herbacea. It structure has been determined by degradation studies and spectroscopic methods. The synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf6d46386ef40975a63ed07d4a8eda6e
https://doi.org/10.1002/hlca.19770600238
https://doi.org/10.1002/hlca.19770600238
Publikováno v:
Zeitschrift für Naturforschung B. 15:560-568
After addition of propionic acid-[1-14C-3-T] to cultures of Streptomyces erythreus the 14C/T ratio in the isolated erythromycin was determined and Kuhn -Roth oxidation was carried out to determine the location of the 14C and T activity in the molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dea054d0387f3ece64ef81d6bb06427
https://doi.org/10.1515/znb-1960-0904
https://doi.org/10.1515/znb-1960-0904
Autor:
Werner Hofheinz, Isenring Hans Peter
Publikováno v:
Synthesis. 1981:385-387
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d5183fc0a9dd963b2da409b7f6d819
https://doi.org/10.1055/s-1981-29461
https://doi.org/10.1055/s-1981-29461
Autor:
Werner Hofheinz, Gottfried Oesterhelt
Publikováno v:
Helvetica Chimica Acta. 62:1307-1309
24-Isopropycholesterol (1) and 22-dehydro-24-isopropylcholesterol 2 have been isolated as the only sterols from an Australian sponge of the genus Pseudaxinyssa. Structures have been deduced from spectroscopic data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::458d9045e9286a0872d833aeedd0cc53
https://doi.org/10.1002/hlca.19790620443
https://doi.org/10.1002/hlca.19790620443
Autor:
Hans Grisebach, Werner Hofheinz
Publikováno v:
Tetrahedron Letters. 3:377-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15eb1f33eb1e371694bdfb9a001bc5bb
https://doi.org/10.1016/s0040-4039(00)70885-9
https://doi.org/10.1016/s0040-4039(00)70885-9